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Half of the animals were treated from days 0 to 4 by the oral administration, twice daily, of 200\u200aml of a glucogenic mixture containing 70% of glycerol, 20% of 1,2-propanediol and 10% of water; the control group received 200\u200aml water. The mean (\u00b1s.e.m.) plasma glucose increased immediately after the first administration (3.9\u00b10.3 vs 3.0\u00b10.1\u200ammol\/l in control group, P&amp;lt;0.05), remaining statistically different during the treatment. However, plasma ghrelin levels were similar in both groups. On the other hand, the results indicated that short-term energy inputs modify ovulation rate (1.9\u00b10.1 vs 1.3\u00b10.2 in control group, P&amp;lt;0.05) by increasing the number of follicles able to be selected to ovulate during the period of treatment (\u22654\u200amm in size; 5.9\u00b10.6 vs 4.3\u00b10.4 at day 2, P&amp;lt;0.05). After sponge withdrawal, the number of these follicles decreased throughout follicular phase (5.8\u00b10.8 to 1.5\u00b10.4, P&amp;lt;0.0005) while the number of large follicles increased (\u22656\u200amm in size; 0.8\u00b10.4 to 2.0\u00b10.3, P&amp;lt;0.05); this would indicate an active growth of preovulatory follicles that were not found in the control group. Thus, the increases of ovulation rate by high-energy inputs would be caused by an enhancement in the developmental competence of preovulatory follicles.<\/jats:p>","DOI":"10.1530\/rep-08-0010","type":"journal-article","created":{"date-parts":[[2008,4,11]],"date-time":"2008-04-11T11:48:19Z","timestamp":1207914499000},"page":"65-72","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-11","source":"Crossref","is-referenced-by-count":31,"title":["Glucogenic supply increases ovulation rate by modifying follicle recruitment and subsequent development of preovulatory follicles without effects on ghrelin secretion"],"prefix":"10.1093","volume":"136","author":[{"given":"C","family":"Letelier","sequence":"first","affiliation":[{"name":"Departamento de Reproducci\u00f3n Animal INIA, 28040 Madrid, Spain 2Instituto de Ciencia Animal y Tecnolog\u00eda de Carnes Universidad Austral de Chile, Casilla 567, Valdivia, Chile 3Departamento de Biolog\u00eda Funcional y Ciencias de la Salud Universidad de Vigo, 36310 Vigo, Spain and 4Departamento de Toxicolog\u00eda y Farmacolog\u00eda Universidad Complutense de Madrid, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Mallo","sequence":"additional","affiliation":[{"name":"Departamento de Reproducci\u00f3n Animal INIA, 28040 Madrid, Spain 2Instituto de Ciencia Animal y Tecnolog\u00eda de Carnes Universidad Austral de Chile, Casilla 567, Valdivia, Chile 3Departamento de Biolog\u00eda Funcional y Ciencias de la Salud Universidad de Vigo, 36310 Vigo, Spain and 4Departamento de Toxicolog\u00eda y Farmacolog\u00eda Universidad Complutense de Madrid, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Encinas","sequence":"additional","affiliation":[{"name":"Departamento de Reproducci\u00f3n Animal INIA, 28040 Madrid, Spain 2Instituto de Ciencia Animal y Tecnolog\u00eda de Carnes Universidad Austral de Chile, Casilla 567, Valdivia, Chile 3Departamento de Biolog\u00eda Funcional y Ciencias de la Salud Universidad de Vigo, 36310 Vigo, Spain and 4Departamento de Toxicolog\u00eda y Farmacolog\u00eda Universidad Complutense de Madrid, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J M","family":"Ros","sequence":"additional","affiliation":[{"name":"Departamento de Reproducci\u00f3n Animal INIA, 28040 Madrid, Spain 2Instituto de Ciencia Animal y Tecnolog\u00eda de Carnes Universidad Austral de Chile, Casilla 567, Valdivia, Chile 3Departamento de Biolog\u00eda Funcional y Ciencias de la Salud Universidad de Vigo, 36310 Vigo, Spain and 4Departamento de Toxicolog\u00eda y Farmacolog\u00eda Universidad Complutense de Madrid, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Gonzalez-Bulnes","sequence":"additional","affiliation":[{"name":"Departamento de Reproducci\u00f3n Animal INIA, 28040 Madrid, Spain 2Instituto de Ciencia Animal y Tecnolog\u00eda de Carnes Universidad Austral de Chile, Casilla 567, Valdivia, Chile 3Departamento de Biolog\u00eda Funcional y Ciencias de la Salud Universidad de Vigo, 36310 Vigo, Spain and 4Departamento de Toxicolog\u00eda y Farmacolog\u00eda Universidad Complutense de Madrid, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2008,7,1]]},"reference":[{"key":"2026010712474145100_bib1"},{"key":"2026010712474145100_bib2","first-page":"403","article-title":"Interactions between nutrition and ovarian activity in cattle: physiological, cellular and mollecular mechanism","volume":"61","author":"Armstrong","year":"2003","journal-title":"Reproduction Supplement"},{"key":"2026010712474145100_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mce.2004.07.015","article-title":"Ghrelin and reproduction: a novel signal linking energy status and 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