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Some studies reveal that adequate glucose uptake and metabolism are essential for the proper differentiation of the uterine endometrium toward a receptive state capable of supporting embryo implantation. However, the mechanistic role of GLUTs in endometrial function remains poorly understood. This review aims to present the current knowledge about GLUT expression in the uterus and distribution among the different cell types within the endometrium. In addition, it analyzes the available data in the context of roles GLUTs may play in normal uterine physiology as well as the pathological conditions of infertility, endometrial cancer, and polycystic ovarian syndrome.<\/jats:p>","DOI":"10.1530\/rep-11-0114","type":"journal-article","created":{"date-parts":[[2011,6,3]],"date-time":"2011-06-03T22:35:08Z","timestamp":1307140508000},"page":"211-220","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":106,"title":["Glucose transporters in the uterus: an analysis of tissue distribution and proposed physiological roles"],"prefix":"10.1093","volume":"142","author":[{"given":"Antonina I","family":"Frolova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelle H","family":"Moley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2011,8,1]]},"reference":[{"key":"2026010712555868500_bib1","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1097\/MED.0b013e3283327fc5","article-title":"Recurrent first trimester pregnancy loss: revised definitions and novel causes","volume":"16","author":"Allison","year":"2009","journal-title":"Current Opinion in Endocrinology, Diabetes, and Obesity"},{"key":"2026010712555868500_bib2","doi-asserted-by":"crossref","first-page":"16519","DOI":"10.1021\/bi962210n","article-title":"Structure\u2013function analysis of liver-type (GLUT2) and brain-type (GLUT3) glucose transporters: expression of chimeric transporters in Xenopus oocytes suggests an important role for putative transmembrane helix 7 in determining substrate selectivity","volume":"35","author":"Arbuckle","year":"1996","journal-title":"Biochemistry"},{"key":"2026010712555868500_bib3","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/iub.315","article-title":"The protein family of glucose transport facilitators: it's not only about glucose after all","volume":"62","author":"Augustin","year":"2010","journal-title":"IUBMB Life"},{"key":"2026010712555868500_bib4","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1111\/j.1600-0854.2005.00354.x","article-title":"GLUT8 contains a [DE]XXXL[LI] sorting motif and localizes to a late endosomal\/lysosomal compartment","volume":"6","author":"Augustin","year":"2005","journal-title":"Traffic"},{"key":"2026010712555868500_bib5","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1093\/oxfordjournals.humrep.a138174","article-title":"Miscarriage rates following in vitro fertilization are increased in women with polycystic ovaries and reduced by pituitary desensitization with buserelin","volume":"8","author":"Balen","year":"1993","journal-title":"Human Reproduction"},{"key":"2026010712555868500_bib6","doi-asserted-by":"crossref","first-page":"2979","DOI":"10.1002\/1097-0142(19931115)72:10<2979::AID-CNCR2820721020>3.0.CO;2-X","article-title":"Overexpression of Glut-1 glucose transporter in human breast cancer. 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