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Morphokinetics, i.e. analysis of the dynamics of cleavage divisions and processes such as compaction and cavitation, has provided both biologists and clinicians with a new set of data regarding embryonic behaviour during preimplantation development and its association with embryo quality. In the current review, we focus on biological significance of morphokinetic parameters and show how they can be used to predict a reproductive outcome. We also explain the statistics behind the predictive algorithms and discuss the future perspectives of morphokinetics.<\/jats:p>","DOI":"10.1530\/rep-17-0004","type":"journal-article","created":{"date-parts":[[2017,4,13]],"date-time":"2017-04-13T20:20:15Z","timestamp":1492114815000},"page":"R37-R53","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":69,"title":["Time-lapse imaging of cleavage divisions in embryo quality assessment"],"prefix":"10.1093","volume":"154","author":[{"given":"Robert","family":"Milewski","sequence":"first","affiliation":[{"name":"Department of Statistics and Medical Informatics , Medical University of Bialystok, Bialystok, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Ajduk","sequence":"additional","affiliation":[{"name":"Department of Embryology , Faculty of Biology, University of Warsaw, Warsaw, 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