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This study uses integrative analysis of preeclampsia transcriptomes and single-cell transcriptomes to predict cell type-specific contributions to preeclampsia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>Preeclampsia is a devastating pregnancy disorder and a major cause of maternal and perinatal mortality. By combining previous transcriptomic results on preeclampsia with single-cell sequencing data, we here predict distinct and partly unanticipated contributions of decidual stromal cells and uterine natural killer cells in early- and late-onset preeclampsia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1530\/rep-22-0079","type":"journal-article","created":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T06:27:47Z","timestamp":1663309667000},"page":"V9-V13","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-11","source":"Crossref","is-referenced-by-count":3,"title":["Cell type markers indicate distinct contributions of decidual stromal cells and natural killer cells in preeclampsia"],"prefix":"10.1093","volume":"164","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5138-0889","authenticated-orcid":false,"given":"Kalle T","family":"Rytk\u00f6nen","sequence":"first","affiliation":[{"name":"Turku Bioscience Centre , University of Turku and \u00c5bo Akademi University, Turku, Finland"},{"name":"Institute of Biomedicine , Research Centre for Integrative Physiology and Pharmacology, University of Turku, Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nigatu","family":"Adossa","sequence":"additional","affiliation":[{"name":"Turku Bioscience Centre , University of Turku and \u00c5bo Akademi University, Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7650-1862","authenticated-orcid":false,"given":"Mehrad","family":"Mahmoudian","sequence":"additional","affiliation":[{"name":"Turku Bioscience Centre , University of Turku and \u00c5bo Akademi University, Turku, Finland"},{"name":"Institute of Biomedicine , Research Centre for Integrative Physiology and Pharmacology, University of Turku, Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tapio","family":"L\u00f6nnberg","sequence":"additional","affiliation":[{"name":"Turku Bioscience Centre , University of Turku and \u00c5bo Akademi University, Turku, Finland"},{"name":"InFLAMES Research Flagship Center , University of Turku, Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matti","family":"Poutanen","sequence":"additional","affiliation":[{"name":"Institute of Biomedicine , Research Centre for Integrative Physiology and Pharmacology, University of Turku, Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura L","family":"Elo","sequence":"additional","affiliation":[{"name":"Turku Bioscience Centre , University of Turku and \u00c5bo Akademi University, Turku, Finland"},{"name":"InFLAMES Research Flagship Center , University of Turku, Turku, Finland"},{"name":"Institute of Biomedicine , University of Turku, Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,10,17]]},"reference":[{"key":"2026010712073254100_bib1","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.placenta.2016.02.012","article-title":"What was the ancestral function of decidual stromal cells? 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