{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T22:32:08Z","timestamp":1767825128854,"version":"3.49.0"},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[1974,2,1]],"date-time":"1974-02-01T00:00:00Z","timestamp":128908800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":["reproduction-online.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1974,2,1]]},"abstract":"<jats:p>The first mammalian embryos to be successfully frozen and thawed were those of the mouse (Whittingham, 1971a; Whittingham, Leibo &amp; Mazur, 1972; Wilmut, 1972). Live young were obtained from mouse embryos which had been stored for up to 8 days at \u2212196\u00b0C, after subsequent thawing and transfer to suitably prepared foster mothers (Whittingham et al., 1972). We now report the first successful transatlantic aerial shipment of two inbred strains of mice as frozen eight-cell embryos and their survival after storage for up to 8 months at \u2212196\u00b0C.<\/jats:p>\n                  <jats:p>Eight-cell mouse embryos were obtained from two inbred strains of mice (C57BL\/6J\u00d7C57BL\/6J and BALB\/cWt \u00d7 BALB\/cWt) at the Jackson Laboratory, Bar Harbor, Maine, U.S.A. They were flushed from the oviducts of naturally mated females on the morning of the second day after finding the coital plug.<\/jats:p>","DOI":"10.1530\/jrf.0.0360433","type":"journal-article","created":{"date-parts":[[2007,5,15]],"date-time":"2007-05-15T17:27:02Z","timestamp":1179250022000},"page":"433-435","update-policy":"https:\/\/doi.org\/10.1530\/rep\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":19,"title":["LONG-TERM STORAGE AND AERIAL TRANSPORT OF FROZEN MOUSE EMBRYOS"],"prefix":"10.1093","volume":"36","author":[{"given":"D. G.","family":"WHITTINGHAM","sequence":"first","affiliation":[]},{"given":"W. K.","family":"WHITTEN","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[1974,2,1]]},"container-title":["Reproduction"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/reproduction\/article-pdf\/36\/2\/433\/64929045\/jrf_36_2_025.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/reproduction\/article-pdf\/36\/2\/433\/64929045\/jrf_36_2_025.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T21:10:20Z","timestamp":1767820220000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/reproduction\/article\/36\/2\/433\/8288498"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1974,2,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1974,2,1]]}},"URL":"https:\/\/doi.org\/10.1530\/jrf.0.0360433","relation":{},"ISSN":["1470-1626","1741-7899"],"issn-type":[{"value":"1470-1626","type":"print"},{"value":"1741-7899","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1974,2,1]]},"published":{"date-parts":[[1974,2,1]]}}}