{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T10:15:16Z","timestamp":1766398516694,"version":"3.48.0"},"reference-count":0,"publisher":"IMR Press","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HSF"],"abstract":"<p class=\"p1\"><span class=\"s1\"><strong>Background:<\/strong> The inspiratory oxygen fraction (FiO<sub>2<\/sub>) is usually set between 60% and 100% during conventional extracorporeal circulation (ECC). However, this strategy causes partial oxygen pressure (PaO<sub>2<\/sub>) to reach hyperoxemic levels (&gt;180 mmHg). During anesthetic management of cardiothoracic surgery it is important to keep PaO<sub>2<\/sub> levels between 80-180 mmHg. The aim of this study was to assess whether adjusting FiO<sub>2<\/sub> levels in accordance with body temperature and body surface area (BSA) during ECC is an effective method for maintaining normoxemic PaO<sub>2<\/sub> during cardiac surgery.<\/span><\/p><p class=\"p1\"><span class=\"s1\"><strong>Methods:<\/strong> After approval from the Ethics Committee of the University of Ac\u0131badem, informed consent was given from 60 patients. FiO<sub>2<\/sub> adjustment strategies applied to the patients in the groups were as follows: FiO<sub>2<\/sub> levels were set as 0.21 \u00d7 BSA during hypothermia and 0.21 \u00d7 BSA + 10 during rewarming in Group I; 0.18 \u00d7 BSA during hypothermia and 0.18 \u00d7 BSA + 15 during rewarming in Group II; and 0.18 \u00d7 BSA during hypothermia and variable with body temperature during rewarming in Group III. Arterial blood gas values and hemodynamic parameters were recorded before ECC (T1); at the 10th minute of cross clamp (T2); when the esophageal temperature (OT) reached 34\u00b0C (T3); when OT reached 36\u00b0C (T4); and just before the cessation of ECC (T5).<\/span><\/p><p class=\"p1\"><span class=\"s1\"><strong>Results:<\/strong> Mean PaO<sub>2<\/sub> was significantly higher in Group I than in Group II at T2 and T3 (<em>P<\/em> = .0001 and <em>P<\/em> = .0001, respectively); in Group I than in Group III at T1 (<em>P<\/em> = .02); and in Group II than in Group III at T2, T3, and T4 <br \/> (<em>P<\/em> = .0001 for all).\u00a0<\/span><\/p><p class=\"p1\"><span class=\"s1\"><strong>Conclusion: <\/strong>Adjustment of FiO<sub>2<\/sub> according to BSA rather than keeping it at a constant level is more appropriate for keeping PaO<sub>2<\/sub> between safe level limits. However, since oxygen consumption of cells vary with body temperature, it would be appropriate to set FiO<sub>2<\/sub> levels in concordance with the body temperature in the <br \/> rewarming period.<\/span><\/p><\/jats:p>","DOI":"10.1532\/hsf.1325","type":"journal-article","created":{"date-parts":[[2015,6,26]],"date-time":"2015-06-26T09:03:24Z","timestamp":1435309404000},"page":"098","source":"Crossref","is-referenced-by-count":0,"title":["Oxygen Fraction Adjustment According to Body Surface Area during Extracorporeal Circulation"],"prefix":"10.31083","volume":"18","author":[{"given":"Cem","family":"Ar\u0131t\u00fcrk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serpil Ustalar","family":"\u00d6zgen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Behi\u00e7","family":"Dan\u0131\u015fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasan","family":"Karabulut","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fevzi","family":"Toraman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16242","published-online":{"date-parts":[[2015,6,26]]},"container-title":["The Heart Surgery Forum"],"original-title":[],"link":[{"URL":"http:\/\/journal.hsforum.com\/index.php\/HSF\/article\/viewFile\/1325\/1272","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T10:13:38Z","timestamp":1766398418000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/HSF\/18\/3\/10.1532\/hsf.1325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,26]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2015,6,26]]}},"URL":"https:\/\/doi.org\/10.1532\/hsf.1325","relation":{},"ISSN":["1522-6662","1098-3511"],"issn-type":[{"type":"electronic","value":"1522-6662"},{"type":"print","value":"1098-3511"}],"subject":[],"published":{"date-parts":[[2015,6,26]]}}}