{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T10:21:08Z","timestamp":1766398868778,"version":"3.48.0"},"reference-count":0,"publisher":"IMR Press","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HSF"],"abstract":"<jats:p>It recently has been reported that the in-stent restenosis (ISR) of expanded area after percutaneous coronary intervention (PCI) within six months can become a serious postoperative complication. A real-time quantitative PCR was used to analyze the expression of serum miR-21 in 33 ISR and 37 non-ISR patients after PCI. Expression of miR-21 was significantly higher in the ISR group compared with that in the NISR group, and a similar trend also occurred in factor- (TNF-\u03b1) level, Interleukin -6 (IL-6) level, and plaque area (PLA). However, a contrary trend occurred in the external elastic membrane area (EEM) and minimal lumen area (MLA). This study suggests that the increased expression of serum miR-21 is related to ISR after PCI, and miR-21 can be a new predictor of ISR.<\/jats:p>","DOI":"10.1532\/hsf.3245","type":"journal-article","created":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T19:34:59Z","timestamp":1602704099000},"page":"E756-E762","source":"Crossref","is-referenced-by-count":0,"title":["Circulating microRNA-21 as Stable Blood-Based Markers for Patients With ISR After PCI"],"prefix":"10.31083","volume":"23","author":[{"given":"Xiong","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Ping","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu- Ai","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Xue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16242","published-online":{"date-parts":[[2020,10,14]]},"container-title":["The Heart Surgery Forum"],"original-title":[],"link":[{"URL":"https:\/\/journal.hsforum.com\/index.php\/HSF\/article\/download\/3245\/5931","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journal.hsforum.com\/index.php\/HSF\/article\/download\/3245\/5931","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T10:15:15Z","timestamp":1766398515000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/HSF\/23\/6\/10.1532\/hsf.3245"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,14]]},"references-count":0,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2020,10,8]]}},"URL":"https:\/\/doi.org\/10.1532\/hsf.3245","relation":{},"ISSN":["1522-6662","1098-3511"],"issn-type":[{"type":"electronic","value":"1522-6662"},{"type":"print","value":"1098-3511"}],"subject":[],"published":{"date-parts":[[2020,10,14]]}}}