{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T10:22:25Z","timestamp":1766398945461,"version":"3.48.0"},"reference-count":0,"publisher":"IMR Press","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HSF"],"abstract":"<jats:p>Objective: Acute type A aortic dissection (AAD) is a serious life-threatening cardiovascular emergency with high in-hospital mortality without aggressive clinical treatment. The study intended to identify the relationship between platelet (PLT) to platelet distribution width (PDW) ratio (PPR) and in-hospital mortality in postoperative patients with type A AAD.\nMethods: A total of 171 type A AAD patients were recruited in this retrospective study from January 2017 to December 2019. Receiver operating characteristics (ROC) were exploited to determine the best cut-off value of PPR, and then patients were sub-grouped into the low-PPR group and high-PPR group, according to the optimal value of PPR. Finally, univariate, and multivariate analyses were carried out to examine the prognostic value of PPR.\nResults: The value of PPR was 9.76, and the mortality was statistically higher in the low-PPR group than in the high-PPR group (29.1% vs. 6.0%, P &lt; 0.01). The area under the ROC curve (AUC) of PPR was 0.724 (95% CI, 0.633-0.815; P &lt; 0.001) with a 56.4% sensitivity and 80.6% specificity. Multivariate analysis showed that serum PPR was an independent factor associated with in-hospital mortality (hazard ratio (HR): 1.151; 95% confidence interval (CI): 1.035 -1.297; P = 0.010).\nConclusion: Serum PPR can be used as an independent predictor of in-hospital mortality in postoperative patients with type A AAD.<\/jats:p>","DOI":"10.1532\/hsf.4605","type":"journal-article","created":{"date-parts":[[2022,6,9]],"date-time":"2022-06-09T22:17:30Z","timestamp":1654813050000},"page":"E413-E416","source":"Crossref","is-referenced-by-count":0,"title":["Prognostic Value of Platelet-to-Platelet Distribution Width Ratio in Postoperative Patients with Type A Acute Aortic Dissection"],"prefix":"10.31083","volume":"25","author":[{"given":"Yaman","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohong","family":"Xia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaoxia","family":"Ge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16242","published-online":{"date-parts":[[2022,5,31]]},"container-title":["The Heart Surgery Forum"],"original-title":[],"link":[{"URL":"https:\/\/journal.hsforum.com\/index.php\/HSF\/article\/download\/4605\/7461","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journal.hsforum.com\/index.php\/HSF\/article\/download\/4605\/7461","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T10:16:09Z","timestamp":1766398569000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/HSF\/25\/3\/10.1532\/hsf.4605"}},"subtitle":["PPR is a Prognostic Factor in Type A AAD"],"short-title":[],"issued":{"date-parts":[[2022,5,31]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,5,24]]}},"URL":"https:\/\/doi.org\/10.1532\/hsf.4605","relation":{},"ISSN":["1522-6662","1098-3511"],"issn-type":[{"type":"electronic","value":"1522-6662"},{"type":"print","value":"1098-3511"}],"subject":[],"published":{"date-parts":[[2022,5,31]]}}}