{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T21:43:14Z","timestamp":1767908594287,"version":"3.49.0"},"reference-count":0,"publisher":"IMR Press","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HSF"],"abstract":"<jats:p>Objective: To study the effect of dexmedetomidine (Dex) on perioperative inflammatory response in aortic dissection (AD) patients.\nMethods: From June 2020 to June 2022, 50 patients with Stanford type B AD underwent endovascular stent-graft exclusion (EVAR) at our hospital. They randomly were assigned to two groups (N = 25): the control group (C group) and the Dex group. Patients in the Dex group received 0.5ug\/kg Dex intravenously 10 minutes before induction of anesthesia and 0.5\u00b5g\/kg\/h Dex during the intervention until 15 minutes before the end of surgery. In contrast, the C group received the same volume of normal saline at the same time points. The two groups were induced and maintained with the same anesthetic agents. Venous blood samples were taken 3 days before operation (T1), 1 day before operation (T2), 1 day after operation (T3) and 3 days after operation (T4) to detect levels of C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and white blood cell count (WBC).\nResults: At T3 and T4, CRP and ESR in the Dex group were significantly improved compared with those in the C group.\nConclusion: Dexmedetomidine can reduce the inflammatory reaction of aortic dissection.<\/jats:p>","DOI":"10.1532\/hsf.5025","type":"journal-article","created":{"date-parts":[[2022,12,15]],"date-time":"2022-12-15T23:10:36Z","timestamp":1671145836000},"page":"E829-E832","source":"Crossref","is-referenced-by-count":6,"title":["Effect of Dexmedetomidine on Inflammatory Response in Aortic Dissection"],"prefix":"10.31083","volume":"25","author":[{"given":"Lulu","family":"Gao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baihan","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiang","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoying","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16242","published-online":{"date-parts":[[2022,12,15]]},"container-title":["The Heart Surgery Forum"],"original-title":[],"link":[{"URL":"https:\/\/journal.hsforum.com\/index.php\/HSF\/article\/download\/5025\/7651","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journal.hsforum.com\/index.php\/HSF\/article\/download\/5025\/7651","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T10:16:22Z","timestamp":1766398582000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/HSF\/25\/6\/10.1532\/hsf.5025"}},"subtitle":["Dexmedetomidine Reduces Inflammation in Aortic Dissection"],"short-title":[],"issued":{"date-parts":[[2022,12,15]]},"references-count":0,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2023,1,5]]}},"URL":"https:\/\/doi.org\/10.1532\/hsf.5025","relation":{},"ISSN":["1522-6662","1098-3511"],"issn-type":[{"value":"1522-6662","type":"electronic"},{"value":"1098-3511","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12,15]]}}}