{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T23:29:58Z","timestamp":1781911798235,"version":"3.54.5"},"reference-count":14,"publisher":"IMR Press","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HSF"],"abstract":"<jats:p>The aim of the study was to review our experience with atrial septal defect (ASD) closure with a fenestrated patch in patients with severe pulmonary hypertension. Between July 2004 and February 2009, 16 patients with isolated ASD underwent closure with a fenestrated patch. All patients had a secundum type ASD and severe pulmonary hypertension. Patients ranged in age from 6 to 57 years (mean \ufffd SD, 34.9 \ufffd 13.5 years). The follow-up period was 9 to 59 months (mean, 34.5 \ufffd 13.1 months). The ranges of preoperative systolic and pulmonary arterial pressures were 63 to 119 mm Hg (mean, 83.8 \ufffd 13.9 mm Hg) and 37 to 77 mm Hg (mean, 51.1 \ufffd 10.1 mm Hg). The ranges of preoperative values for the ratio of the pulmonary flow to the systemic flow and for pulmonary arterial resistance were 1.1 to 2.7 (mean, 1.95 \ufffd 0.5) and 3.9 to 16.7 Wood units (mean, 9.8 \ufffd 2.9 Wood units), respectively. There was no early or late mortality. Tricuspid annuloplasty was performed in 14 patients (87.5%). The peak tricuspid regurgitation gradient and the ratio of the systolic pulmonary artery pressure to the systemic arterial pressure were decreased in all patients. The New York Heart Association class and the grade of tricuspid regurgitation were improved in 13 patients (81.2%) and 15 patients (93.7%), respectively. ASD closure in patients with severe pulmonary hypertension can be performed safely if we create fenestration. Tricuspid annuloplasty and a Cox maze procedure may improve the clinical result. Close observation and follow-up will be needed to validate the long-term benefits.<\/jats:p>","DOI":"10.1532\/hsf98.20111085","type":"journal-article","created":{"date-parts":[[2012,4,27]],"date-time":"2012-04-27T22:44:09Z","timestamp":1335566649000},"page":"111","source":"Crossref","is-referenced-by-count":24,"title":["Surgical Strategy in Patients with Atrial Septal Defect and Severe Pulmonary Hypertension"],"prefix":"10.31083","volume":"15","author":[{"given":"Yang Hyun","family":"Cho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae-Gook","family":"Jun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Hyuk","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pyo Won","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"June","family":"Huh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I-Seok","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heung Jae","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16242","published-online":{"date-parts":[[2012,4,26]]},"reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1378\/chest.07-1222","article-title":"Long-term follow-up of a fenestrated Amplatzer atrial septal occluder in pulmonary arterial hypertension","volume":"133","author":"T. Altoff","year":"2008","journal-title":"Chest"},{"key":"2","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1016\/S0735-1097(01)01635-7","article-title":"Surgical treatment for secundum atrial septal defects in patients >40 years old. A randomized clinical trial","volume":"38","author":"F. Attie","year":"2001","journal-title":"J Am Coll Cardiol"},{"key":"3","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/j.jacc.2008.11.025","article-title":"Eisenmenger syndrome: a clinical perspective in a new therapeutic era of pulmonary arterial hypertension","volume":"53","author":"M. Beghetti","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"4","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/j.1540-8183.2007.00324.x","article-title":"Fenestrated occluders for treatment of ASD in elderly patients with pulmonary hypertension and\/or right heart failure","volume":"21","author":"L. 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