{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T10:14:49Z","timestamp":1766398489966,"version":"3.48.0"},"reference-count":21,"publisher":"IMR Press","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HSF"],"abstract":"<p><strong>Background:<\/strong> Ischemic heart disease is a significant complication of atherosclerosis. Myocardial infarction after the development of coronary artery disease can lead to a number of serious complications, including ischemic mitral regurgitation (IMR). Currently there is no consensus regarding the preferred therapeutic modality for moderately severe IMR. In this study, the postoperative outcome of concomitant coronary artery bypass (CABG) and mitral valve repair was compared with that of CABG alone in two groups of patients with moderately severe IMR.<\/p><p><strong>Methods:<\/strong> A total of 84 patients who underwent operations for coronary artery disease and moderately severe IMR were included in the study. Preoperative demographic and clinical characteristics were recorded at the time of admission. The severity of mitral regurgitation was graded using transthoracic echocardiography and left ventriculography.<\/p><p><strong>Results:<\/strong> Significant postoperative improvements were observed in ejection fraction and systolic diameter compared to preoperative values (<em>P<\/em> = .006 and <em>P<\/em> = .020 respectively, in the intervention group, <em>P<\/em> = .001 and <em>P<\/em> = .001 respectively, in the control group). The decrease in pulmonary artery pressure (PAP) was significant only in the intervention group (<em>P<\/em> = .001). There was a significantly marked reduction in the severity of IMR in the intervention group compared to control.<\/p><p><strong>Conclusion:<\/strong> Surgical repair of the mitral valve in conjunction with CABG for moderately severe IMR appears to be more effective than isolated CABG for certain outcome parameters, including decreased severity of mitral regurgitation and decreased pulmonary artery pressure.<\/p><\/jats:p>","DOI":"10.1532\/hsf98.2014337","type":"journal-article","created":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T21:01:00Z","timestamp":1409605260000},"page":"201","source":"Crossref","is-referenced-by-count":6,"title":["Surgical Strategy for Moderate Ischemic Mitral Valve Regurgitation: Repair or Ignore?"],"prefix":"10.31083","volume":"17","author":[{"given":"Adem \u0130","family":"Diken","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Garip","family":"Alt\u0131nta\u015f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adnan","family":"Yal\u00e7\u0131nkaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00f6khan","family":"Laf\u00e7\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Onur","family":"Hanedan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerim","family":"\u00c7a\u011fl\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16242","published-online":{"date-parts":[[2014,9,1]]},"reference":[{"issue":"11","key":"1","article-title":"Improving outcomes in patients with moderate ischemic mitral regurgitation undergoing combined CABG and mitral annuloplasty","volume":"102","author":"D. Adams","year":"2000","journal-title":"Circulation"},{"key":"2","doi-asserted-by":"crossref","DOI":"10.1161\/hc37t1.094706","article-title":"Does coronary artery bypass grafting alone correct moderate ischaemic mitral regurgitation?","volume":"104","author":"L. Aklog","year":"2001","journal-title":"Circulation"},{"key":"3","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/0002-9149(90)90968-7","article-title":"Prognostic significance of mitral regurgitation in acute myocardial infarction. The MILIS Study Group","volume":"65","author":"B. Barzilai","year":"1990","journal-title":"Am J Cardiol"},{"key":"4","first-page":"427","article-title":"Results following valve replacement for ischaemic mitral regurgitation","volume":"17","author":"D. Bouchard","year":"2001","journal-title":"Can J Cardiol"},{"key":"5","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.ejcts.2004.12.031","article-title":"Preoperative left ventricular dimensions predict reverse remodelling following restrictive mitral annuloplasty in ischaemic mitral regurgitation","volume":"27","author":"J. Braun","year":"2005","journal-title":"Eur J Cardiothorac Surg"},{"key":"6","doi-asserted-by":"crossref","first-page":"2128","DOI":"10.1016\/j.athoracsur.2006.01.061","article-title":"Impact of no to moderate mitral regurgitation on late results after isolated coronary artery bypass grafting in patients with ischemic cardiomyopathy","volume":"81","author":"M. Di Mauro","year":"2006","journal-title":"Ann Thorac Surg"},{"key":"7","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/S0003-4975(99)00516-0","article-title":"Treatment of moderate mitral regurgitation and coronary disease by coronary bypass alone: late results","volume":"68","author":"I. Duarte","year":"1999","journal-title":"Ann Thorac Surg"},{"key":"8","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1067\/mtc.2001.116557","article-title":"Is repair preferable to replacement for ischaemic mitral regurgitation?","volume":"122","author":"A. Gillinov","year":"2001","journal-title":"J Thorac Cardiovasc Surg"},{"key":"9","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1016\/S0003-4975(02)03920-6","article-title":"Can late survival of patients with moderate ischemic mitral regurgitation be impacted by intervention on the valve?","volume":"74","author":"K. Harris","year":"2002","journal-title":"Ann Thorac Surg"},{"key":"10","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCULATIONAHA.105.000398","article-title":"Mitral valve repair vs. revascularization alone in the treatment of ischemic mitral regurgitation","volume":"114","author":"D. Kang","year":"2006","journal-title":"Circulation"},{"key":"11","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1016\/j.athoracsur.2004.11.005","article-title":"Ischemic mitral regurgitation: revascularization alone versus revascularization and mitral valve repair","volume":"79","author":"Y. Kim","year":"2005","journal-title":"Ann Thorac Surg"},{"key":"12","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.athoracsur.2004.07.040","article-title":"Importance of moderate ischemic mitral regurgitation","volume":"69","author":"B. Lam","year":"2005","journal-title":"Ann Thorac Surg"},{"key":"13","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1136\/heart.89.4.459","article-title":"Management of ischaemic mitral regurgitation","volume":"89","author":"B. Lung","year":"2003","journal-title":"Heart"},{"key":"14","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.jtcvs.2003.09.010","article-title":"Late outcomes in patients with uncorrected mild to moderate mitral regurgitation at the time of isolated coronary artery bypass grafting","volume":"127","author":"H. Mallidi","year":"2004","journal-title":"J Thorac Cardiovasc Surg"},{"key":"15","first-page":"143","article-title":"Coronary artery bypass grafting alone for advanced ischemic left ventricular dysfunction with significant mitral regurgitation: early and mid-term outcomes in a small series","volume":"1","author":"N. Ogus","year":"2004","journal-title":"Tex Heart Inst J"},{"key":"16","first-page":"754","article-title":"Ischemic mitral valve regurgitation grade II-III: correction in patients with impaired left ventricular function undergoing simultaneous coronary revascularization","volume":"10","author":"E. Prifti","year":"2001","journal-title":"J Heart Valve Dis"},{"key":"17","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/S1010-7940(01)00770-9","article-title":"The importance of grade 2 ischemic mitral regurgitation in coronary artery bypass grafting","volume":"20","author":"T. Ryden","year":"2001","journal-title":"Eur J Cardiothorac Surg"},{"key":"18","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCULATIONAHA.104.523472","article-title":"Impact of mitral valve regurgitation evaluated by Intraoperative transesophageal echocardiography on long-term outcomes after coronary artery bypass grafting","volume":"112","author":"J. Schroder","year":"2005","journal-title":"Circulation"},{"key":"19","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/0002-9149(64)90027-X","article-title":"Left retrograde cardioangiography in acquired cardiac disease: technic, indications and interpretations in 700 cases","volume":"14","author":"R. Sellers","year":"1964","journal-title":"Am J Cardiol"},{"key":"20","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1080\/14017430802430943","article-title":"The prevalence of moderate mitral regurgitation in patients undergoing CABG","volume":"43","author":"P. Wierup","year":"2009","journal-title":"Scand Cardiovasc J"},{"key":"21","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.athoracsur.2005.03.034","article-title":"Long-term survival after surgical revascularization for moderate ischemic mitral regurgitation","volume":"80","author":"D. Wong","year":"2005","journal-title":"Ann Thorac Surg"}],"container-title":["The Heart Surgery Forum"],"original-title":[],"link":[{"URL":"http:\/\/journal.hsforum.com\/index.php\/HSF\/article\/viewFile\/147\/146","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T10:13:12Z","timestamp":1766398392000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.imrpress.com\/journal\/HSF\/17\/4\/10.1532\/HSF98.2014337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,1]]},"references-count":21,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2014,8,1]]}},"URL":"https:\/\/doi.org\/10.1532\/hsf98.2014337","relation":{},"ISSN":["1522-6662","1098-3511"],"issn-type":[{"type":"electronic","value":"1522-6662"},{"type":"print","value":"1098-3511"}],"subject":[],"published":{"date-parts":[[2014,9,1]]}}}