{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T06:53:57Z","timestamp":1785826437184,"version":"3.56.0"},"reference-count":146,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cell sheet morphogenesis characterizes key developmental transitions and homeostasis, in vertebrates and throughout phylogeny, including gastrulation, neural tube formation and wound healing. Dorsal closure, a process during Drosophila embryogenesis, has emerged as a model for cell sheet morphogenesis. \u223c140 genes are currently known to affect dorsal closure and new genes are identified each year. Many of these genes were identified in screens that resulted in arrested development. Dorsal closure is remarkably robust and many questions regarding the molecular mechanisms involved in this complex biological process remain. Thus, it is important to identify all genes that contribute to the kinematics and dynamics of closure. Here, we used a set of large deletions (deficiencies), which collectively remove 98.5% of the genes on the right arm of Drosophila melanogaster\u2019s 2nd chromosome to identify \u201cdorsal closure deficiencies\u201d. Through two crosses, we unambiguously identified embryos homozygous for each deficiency and time-lapse imaged them for the duration of closure. Images were analyzed for defects in cell shapes and tissue movements. Embryos homozygous for 47 deficiencies have notable, diverse defects in closure, demonstrating that a number of discrete processes comprise closure and are susceptible to mutational disruption. Further analysis of these deficiencies will lead to the identification of at least 30 novel \u201cdorsal closure genes\u201d. We expect that many of these novel genes will identify links to pathways and structures already known to coordinate various aspects of closure. We also expect to identify new processes and pathways that contribute to closure.<\/jats:p>","DOI":"10.1534\/g3.118.200233","type":"journal-article","created":{"date-parts":[[2018,5,18]],"date-time":"2018-05-18T21:30:15Z","timestamp":1526679015000},"page":"2361-2387","source":"Crossref","is-referenced-by-count":6,"title":["Identifying Genetic Players in Cell Sheet Morphogenesis Using a<i>Drosophila<\/i>Deficiency Screen for Genes on Chromosome 2R Involved in Dorsal Closure"],"prefix":"10.1093","volume":"8","author":[{"given":"Richard D","family":"Mortensen","sequence":"first","affiliation":[{"name":"Biology Department, Duke University, Durham, NC, 27708, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regan P","family":"Moore","sequence":"additional","affiliation":[{"name":"Biology Department, Duke University, Durham, NC, 27708, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie M","family":"Fogerson","sequence":"additional","affiliation":[{"name":"Biology Department, Duke University, Durham, NC, 27708, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hellen Y","family":"Chiou","sequence":"additional","affiliation":[{"name":"Biology Department, Duke University, Durham, NC, 27708, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chimdindu V","family":"Obinero","sequence":"additional","affiliation":[{"name":"Biology Department, Duke University, Durham, NC, 27708, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neel K","family":"Prabhu","sequence":"additional","affiliation":[{"name":"Biology Department, Duke University, Durham, NC, 27708, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela H","family":"Wei","sequence":"additional","affiliation":[{"name":"Biology Department, Duke University, Durham, NC, 27708, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janice M","family":"Crawford","sequence":"additional","affiliation":[{"name":"Biology Department, Duke University, Durham, NC, 27708, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel P","family":"Kiehart","sequence":"additional","affiliation":[{"name":"Biology Department, Duke University, Durham, NC, 27708, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,7,1]]},"reference":[{"key":"2021042013310613600_bib1","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.jtbi.2010.09.029","article-title":"A mathematical model for dorsal closure.","volume":"268","author":"Almeida","year":"2011","journal-title":"J. Theor. Biol."},{"key":"2021042013310613600_bib2","doi-asserted-by":"publisher","first-page":"e23964","DOI":"10.1371\/journal.pone.0023964","article-title":"DRhoGEF2 regulates cellular tension and cell pulsations in the Amnioserosa during Drosophila dorsal closure.","volume":"6","author":"Azevedo","year":"2011","journal-title":"PLoS One"},{"key":"2021042013310613600_bib3","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1073\/pnas.27.11.499","article-title":"Genetic Control of Biochemical Reactions in Neurospora.","volume":"27","author":"Beadle","year":"1941","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021042013310613600_bib4","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.ceb.2016.04.006","article-title":"Mechanics of epithelial tissues during gap closure.","volume":"42","author":"Begnaud","year":"2016","journal-title":"Curr. Opin. Cell Biol."},{"key":"2021042013310613600_bib5","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.devcel.2014.08.015","article-title":"The Dpp\/TGFbeta-dependent corepressor Schnurri protects epithelial cells from JNK-induced apoptosis in drosophila embryos.","volume":"31","author":"Beira","year":"2014","journal-title":"Dev. Cell"},{"key":"2021042013310613600_bib6","doi-asserted-by":"publisher","first-page":"2379","DOI":"10.1002\/dvdy.22753","article-title":"Drosophila as a model of wound healing and tissue regeneration in vertebrates.","volume":"240","author":"Belacortu","year":"2011","journal-title":"Dev. Dyn."},{"key":"2021042013310613600_bib7","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/0092-8674(89)90424-8","article-title":"A purified Drosophila homeodomain protein represses transcription in vitro.","volume":"58","author":"Biggin","year":"1989","journal-title":"Cell"},{"key":"2021042013310613600_bib8","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1006\/dbio.1998.9036","article-title":"The Products of ribbon and raw Are Necessary for Proper Cell Shape and Cellular Localization of Nonmuscle Myosin in Drosophila.","volume":"203","author":"Blake","year":"1998","journal-title":"Dev. Biol."},{"key":"2021042013310613600_bib9","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1038\/nmeth.1327","article-title":"Tissue tectonics: morphogenetic strain rates, cell shape change and intercalation.","volume":"6","author":"Blanchard","year":"2009","journal-title":"Nat. Methods"},{"key":"2021042013310613600_bib10","doi-asserted-by":"publisher","first-page":"2743","DOI":"10.1242\/dev.045872","article-title":"Cytoskeletal dynamics and supracellular organisation of cell shape fluctuations during dorsal closure.","volume":"137","author":"Blanchard","year":"2010","journal-title":"Development"},{"key":"2021042013310613600_bib11","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1016\/j.ydbio.2009.02.013","article-title":"Non-autonomous modulation of heart rhythm, contractility and morphology in adult fruit flies.","volume":"328","author":"Buechling","year":"2009","journal-title":"Dev. Biol."},{"key":"2021042013310613600_bib12","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-662-22489-2","volume-title":"The Embryonic Development of Drosophila Melanogaster","author":"Campos-Ortega","year":"1997"},{"key":"2021042013310613600_bib13","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1242\/dev.125.9.1759","article-title":"A genetic screen for modifiers of Drosophila decapentaplegic signaling identifies mutations in punt, Mothers against dpp and the BMP-7 homologue, 60A.","volume":"125","author":"Chen","year":"1998","journal-title":"Development"},{"key":"2021042013310613600_bib14","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1016\/j.cell.2011.06.040","article-title":"Anaplastic lymphoma kinase spares organ growth during nutrient restriction in Drosophila.","volume":"146","author":"Cheng","year":"2011","journal-title":"Cell"},{"key":"2021042013310613600_bib15","doi-asserted-by":"publisher","first-page":"R21","DOI":"10.1186\/gb-2012-13-3-r21","article-title":"The generation of chromosomal deletions to provide extensive coverage and subdivision of the Drosophila melanogaster genome.","volume":"13","author":"Cook","year":"2012","journal-title":"Genome Biol."},{"key":"2021042013310613600_bib16","doi-asserted-by":"publisher","first-page":"1645","DOI":"10.1242\/dev.044107","article-title":"The PAR complex regulates pulsed actomyosin contractions during amnioserosa apical constriction in Drosophila.","volume":"137","author":"David","year":"2010","journal-title":"Development"},{"key":"2021042013310613600_bib17","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1038\/ncb3421","article-title":"The actin cable is dispensable in directing dorsal closure dynamics but neutralizes mechanical stress to prevent scarring in the Drosophila embryo.","volume":"18","author":"Ducuing","year":"2016","journal-title":"Nat. Cell Biol."},{"key":"2021042013310613600_bib18","doi-asserted-by":"publisher","first-page":"4676","DOI":"10.1242\/dev.136127","article-title":"Integration of actomyosin contractility with cell-cell adhesion during dorsal closure.","volume":"143","author":"Duque","year":"2016","journal-title":"Development"},{"key":"2021042013310613600_bib19","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1016\/j.cub.2004.08.063","article-title":"Terminal cytokinesis events uncovered after an RNAi screen.","volume":"14","author":"Echard","year":"2004","journal-title":"Curr. Biol."},{"key":"2021042013310613600_bib20","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1038\/ncb3159","article-title":"Quantitative analysis of cytoskeletal reorganization during epithelial tissue sealing by large-volume electron tomography.","volume":"17","author":"Eltsov","year":"2015","journal-title":"Nat. Cell Biol."},{"key":"2021042013310613600_bib21","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1038\/nature01950","article-title":"Jeb signals through the Alk receptor tyrosine kinase to drive visceral muscle fusion.","volume":"425","author":"Englund","year":"2003","journal-title":"Nature"},{"key":"2021042013310613600_bib22","doi-asserted-by":"publisher","first-page":"6586","DOI":"10.1038\/srep06586","article-title":"A Halloween gene noppera-bo encodes a glutathione S-transferase essential for ecdysteroid biosynthesis via regulating the behaviour of cholesterol in Drosophila.","volume":"4","author":"Enya","year":"2014","journal-title":"Sci. Rep."},{"key":"2021042013310613600_bib23","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1016\/j.mod.2007.09.002","article-title":"Dpp signalling orchestrates dorsal closure by regulating cell shape changes both in the amnioserosa and in the epidermis.","volume":"124","author":"Fern\u00e1ndez","year":"2007","journal-title":"Mech. Dev."},{"key":"2021042013310613600_bib24","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1101\/gad.14.5.604","article-title":"The Drosophila shark tyrosine kinase is required for embryonic dorsal closure.","volume":"14","author":"Fernandez","year":"2000","journal-title":"Genes Dev."},{"key":"2021042013310613600_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1242\/dev.107.1.1","article-title":"Mitotic domains reveal early commitment of cells in Drosophila embryos.","volume":"107","author":"Foe","year":"1989","journal-title":"Development"},{"key":"2021042013310613600_bib26","doi-asserted-by":"publisher","first-page":"2208","DOI":"10.1016\/j.cub.2005.11.064","article-title":"Nonmuscle myosin II generates forces that transmit tension and drive contraction in multiple tissues during dorsal closure.","volume":"15","author":"Franke","year":"2005","journal-title":"Curr. Biol."},{"key":"2021042013310613600_bib27","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1002\/j.1460-2075.1987.tb04817.x","article-title":"Characterization and localization of the even-skipped protein of Drosophila.","volume":"6","author":"Frasch","year":"1987","journal-title":"EMBO J."},{"key":"2021042013310613600_bib28","doi-asserted-by":"crossref","first-page":"4371","DOI":"10.1242\/dev.121.12.4371","article-title":"Early even-skipped stripes act as morphogenetic gradients at the single cell level to establish engrailed expression.","volume":"121","author":"Fujioka","year":"1995","journal-title":"Development"},{"key":"2021042013310613600_bib29","doi-asserted-by":"publisher","first-page":"2027","DOI":"10.1242\/dev.02849","article-title":"Enabled plays key roles in embryonic epithelial morphogenesis in Drosophila.","volume":"134","author":"Gates","year":"2007","journal-title":"Development"},{"key":"2021042013310613600_bib30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.mce.2003.11.003","article-title":"Halloween genes encode P450 enzymes that mediate steroid hormone biosynthesis in Drosophila melanogaster.","volume":"215","author":"Gilbert","year":"2004","journal-title":"Mol. Cell. Endocrinol."},{"key":"2021042013310613600_bib31","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1002\/dvdy.24363","article-title":"From actomyosin oscillations to tissue-level deformations.","volume":"245","author":"Gorfinkiel","year":"2016","journal-title":"Dev. Dyn."},{"key":"2021042013310613600_bib32","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1016\/j.ceb.2011.06.002","article-title":"Dynamics of actomyosin contractile activity during epithelial morphogenesis.","volume":"23","author":"Gorfinkiel","year":"2011","journal-title":"Curr. Opin. Cell Biol."},{"key":"2021042013310613600_bib33","doi-asserted-by":"publisher","first-page":"1889","DOI":"10.1242\/dev.030866","article-title":"Mechanical control of global cell behaviour during dorsal closure in Drosophila.","volume":"136","author":"Gorfinkiel","year":"2009","journal-title":"Development"},{"key":"2021042013310613600_bib34","doi-asserted-by":"publisher","first-page":"3289","DOI":"10.1242\/jcs.010850","article-title":"Requirements for adherens junction components in the interaction between epithelial tissues during dorsal closure in Drosophila.","volume":"120","author":"Gorfinkiel","year":"2007","journal-title":"J. Cell Sci."},{"issue":"D1","key":"2021042013310613600_bib145","doi-asserted-by":"crossref","first-page":"D663","DOI":"10.1093\/nar\/gkw1016","article-title":"FlyBase at 25: looking to the future.","volume":"45","author":"Gramates","year":"2017","journal-title":"Nucleic Acids Res."},{"key":"2021042013310613600_bib35","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1083\/jcb.200105102","article-title":"Abelson kinase regulates epithelial morphogenesis in Drosophila.","volume":"155","author":"Grevengoed","year":"2001","journal-title":"J. Cell Biol."},{"key":"2021042013310613600_bib36","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1002\/gene.10136","article-title":"New fluorescent protein reporters for use with the Drosophila Gal4 expression system and for vital detection of balancer chromosomes.","volume":"34","author":"Halfon","year":"2002","journal-title":"Genesis"},{"key":"2021042013310613600_bib146","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1093\/genetics\/148.4.1845","article-title":"Second-site noncomplementation identifies genomic regions required for Drosophila nonmuscle myosin function during morphogenesis.","volume":"148","author":"Halsell","year":"1998","journal-title":"Genetics."},{"key":"2021042013310613600_bib37","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1046\/j.1432-0436.2002.700408.x","article-title":"Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila.","volume":"70","author":"Harden","year":"2002","journal-title":"Differentiation"},{"key":"2021042013310613600_bib38","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/B978-0-12-394304-0.00007-5","article-title":"Adherens junction assembly and function in the Drosophila embryo.","volume":"293","author":"Harris","year":"2012","journal-title":"Int. Rev. Cell Mol. Biol."},{"key":"2021042013310613600_bib39","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/S0070-2153(09)89003-0","article-title":"How the cytoskeleton helps build the embryonic body plan: models of morphogenesis from Drosophila.","volume":"89","author":"Harris","year":"2009","journal-title":"Curr. Top. Dev. Biol."},{"key":"2021042013310613600_bib40","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/BF00848246","article-title":"Fate-mapping in wild-type Drosophila melanogaster. I. The spatio-temporal pattern of embryonic cell divisions.","volume":"194","author":"Hartenstein","year":"1985","journal-title":"Roux\u2019s Arch"},{"key":"2021042013310613600_bib41","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1073\/pnas.66.2.352","article-title":"Genetic control of the cell-division cycle in yeast. I. Detection of mutants.","volume":"66","author":"Hartwell","year":"1970","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021042013310613600_bib42","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1242\/dev.111.4.1021","article-title":"Plasma membrane location of the Toll protein in the syncytial Drosophila embryo: importance of transmembrane signaling for dorsal-ventral pattern formation.","volume":"111","author":"Hashimoto","year":"1991","journal-title":"Development"},{"key":"2021042013310613600_bib43","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/j.devcel.2014.12.017","article-title":"Sequential contraction and exchange of apical junctions drives zippering and neural tube closure in a simple chordate.","volume":"32","author":"Hashimoto","year":"2015","journal-title":"Dev. Cell"},{"key":"2021042013310613600_bib44","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.mod.2016.12.005","article-title":"Drosophila dorsal closure: An orchestra of forces to zip shut the embryo.","volume":"144","author":"Hayes","year":"2017","journal-title":"Mech. Dev."},{"key":"2021042013310613600_bib45","doi-asserted-by":"publisher","first-page":"1284","DOI":"10.1002\/bies.200900109","article-title":"Dorsal closure in Drosophila: cells cannot get out of the tight spot.","volume":"31","author":"Heisenberg","year":"2009","journal-title":"BioEssays"},{"key":"2021042013310613600_bib46","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1016\/j.cell.2013.05.008","article-title":"Forces in tissue morphogenesis and patterning.","volume":"153","author":"Heisenberg","year":"2013","journal-title":"Cell"},{"key":"2021042013310613600_bib47","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1002\/dvdy.20649","article-title":"JNK signaling coordinates integrin and actin functions during Drosophila embryogenesis.","volume":"235","author":"Homsy","year":"2006","journal-title":"Dev. Dyn."},{"key":"2021042013310613600_bib48","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1242\/dev.097097","article-title":"Ion channels contribute to the regulation of cell sheet forces during Drosophila dorsal closure.","volume":"141","author":"Hunter","year":"2014","journal-title":"Development"},{"key":"2021042013310613600_bib49","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1126\/science.1079552","article-title":"Forces for morphogenesis investigated with laser microsurgery and quantitative modeling.","volume":"300","author":"Hutson","year":"2003","journal-title":"Science"},{"key":"2021042013310613600_bib50","doi-asserted-by":"publisher","first-page":"1420","DOI":"10.1016\/S0960-9822(00)00796-X","article-title":"Dynamic actin-based epithelial adhesion and cell matching during Drosophila dorsal closure.","volume":"10","author":"Jacinto","year":"2000","journal-title":"Curr. Biol."},{"key":"2021042013310613600_bib51","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1016\/S0960-9822(02)00955-7","article-title":"Dynamic analysis of actin cable function during Drosophila dorsal closure.","volume":"12","author":"Jacinto","year":"2002","journal-title":"Curr. Biol."},{"key":"2021042013310613600_bib52","doi-asserted-by":"publisher","first-page":"2572","DOI":"10.1101\/gad.207301","article-title":"Drosophila separase is required for sister chromatid separation and binds to PIM and THR.","volume":"15","author":"Jager","year":"2001","journal-title":"Genes Dev."},{"key":"2021042013310613600_bib53","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.devcel.2006.07.014","article-title":"Transiently reorganized microtubules are essential for zippering during dorsal closure in Drosophila melanogaster.","volume":"11","author":"Jankovics","year":"2006","journal-title":"Dev. Cell"},{"key":"2021042013310613600_bib54","doi-asserted-by":"publisher","first-page":"e22229","DOI":"10.1371\/journal.pone.0022229","article-title":"A functional genomic screen combined with time-lapse microscopy uncovers a novel set of genes involved in dorsal closure of Drosophila embryos.","volume":"6","author":"Jankovics","year":"2011","journal-title":"PLoS One"},{"key":"2021042013310613600_bib55","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.bpj.2013.05.027","article-title":"Apical oscillations in amnioserosa cells: basolateral coupling and mechanical autonomy.","volume":"105","author":"Jayasinghe","year":"2013","journal-title":"Biophys. J."},{"key":"2021042013310613600_bib56","doi-asserted-by":"publisher","first-page":"2075","DOI":"10.1534\/genetics.104.039735","article-title":"RacGap50C negatively regulates wingless pathway activity during Drosophila embryonic development.","volume":"169","author":"Jones","year":"2005","journal-title":"Genetics"},{"key":"2021042013310613600_bib57","doi-asserted-by":"publisher","first-page":"4496","DOI":"10.1242\/jcs.193268","article-title":"alpha-Catenin stabilises Cadherin-Catenin complexes and modulates actomyosin dynamics to allow pulsatile apical contraction.","volume":"129","author":"Jurado","year":"2016","journal-title":"J. Cell Sci."},{"key":"2021042013310613600_bib58","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1007\/BF00848157","article-title":"Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster: II. Zygotic loci on the third chromosome.","volume":"193","author":"J\u00fcrgens","year":"1984","journal-title":"Wilehm Roux Arch. Dev. Biol."},{"key":"2021042013310613600_bib59","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1242\/jcs.115.11.2257","article-title":"Asymmetric cell division: microtubule dynamics and spindle asymmetry.","volume":"115","author":"Kaltschmidt","year":"2002","journal-title":"J. Cell Sci."},{"key":"2021042013310613600_bib60","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1038\/ncb882","article-title":"Planar polarity and actin dynamics in the epidermis of Drosophila.","volume":"4","author":"Kaltschmidt","year":"2002","journal-title":"Nat. Cell Biol."},{"key":"2021042013310613600_bib61","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1242\/dev.112.2.365","article-title":"Drosophila gastrulation: analysis of cell shape changes in living embryos by three-dimensional fluorescence microscopy.","volume":"112","author":"Kam","year":"1991","journal-title":"Development"},{"key":"2021042013310613600_bib63","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1146\/annurev-cellbio-111315-125357","article-title":"Cell Sheet Morphogenesis: Dorsal Closure in Drosophila melanogaster as a model system.","volume":"33","author":"Kiehart","year":"2017","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"2021042013310613600_bib64","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1083\/jcb.149.2.471","article-title":"Multiple forces contribute to cell sheet morphogenesis for dorsal closure in Drosophila.","volume":"149","author":"Kiehart","year":"2000","journal-title":"J. Cell Biol."},{"key":"2021042013310613600_bib65","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/S0091-679X(08)60929-2","article-title":"High-resolution microscopic methods for the analysis of cellular movements in Drosophila embryos","volume-title":"Methods in Cell Biology","author":"Kiehart","year":"1994"},{"key":"2021042013310613600_bib66","doi-asserted-by":"publisher","first-page":"e1002122","DOI":"10.1371\/journal.pbio.1002122","article-title":"Convergence and extrusion are required for normal fusion of the mammalian secondary palate.","volume":"13","author":"Kim","year":"2015","journal-title":"PLoS Biol."},{"key":"2021042013310613600_bib67","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/0092-8674(94)90239-9","article-title":"Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation.","volume":"77","author":"Knoblich","year":"1994","journal-title":"Cell"},{"key":"2021042013310613600_bib68","doi-asserted-by":"publisher","first-page":"3505","DOI":"10.1091\/mbc.9.12.3505","article-title":"Drosophila coracle, a member of the protein 4.1 superfamily, has essential structural functions in the septate junctions and developmental functions in embryonic and adult epithelial cells.","volume":"9","author":"Lamb","year":"1998","journal-title":"Mol. Biol. Cell"},{"key":"2021042013310613600_bib69","doi-asserted-by":"publisher","first-page":"3255","DOI":"10.1242\/dev.02492","article-title":"Differential expression of the adhesion molecule Echinoid drives epithelial morphogenesis in Drosophila.","volume":"133","author":"Laplante","year":"2006","journal-title":"Development"},{"key":"2021042013310613600_bib70","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1083\/jcb.201009022","article-title":"Asymmetric distribution of Echinoid defines the epidermal leading edge during Drosophila dorsal closure.","volume":"192","author":"Laplante","year":"2011","journal-title":"J. Cell Biol."},{"key":"2021042013310613600_bib71","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1016\/j.cell.2005.04.016","article-title":"Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development.","volume":"121","author":"Leaman","year":"2005","journal-title":"Cell"},{"key":"2021042013310613600_bib72","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1038\/nature01916","article-title":"Jelly belly protein activates the receptor tyrosine kinase Alk to specify visceral muscle pioneers.","volume":"425","author":"Lee","year":"2003","journal-title":"Nature"},{"key":"2021042013310613600_bib73","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1002\/dvdy.22186","article-title":"POSH misexpression induces caspase-dependent cell death in Drosophila.","volume":"239","author":"Lennox","year":"2010","journal-title":"Dev. Dyn."},{"key":"2021042013310613600_bib74","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1093\/genetics\/151.2.685","article-title":"Identification of genes controlling malpighian tubule and other epithelial morphogenesis in Drosophila melanogaster.","volume":"151","author":"Liu","year":"1999","journal-title":"Genetics"},{"key":"2021042013310613600_bib75","doi-asserted-by":"publisher","first-page":"2406","DOI":"10.1016\/j.bpj.2015.10.017","article-title":"Remodeling Tissue Interfaces and the Thermodynamics of Zipping during Dorsal Closure in Drosophila.","volume":"109","author":"Lu","year":"2015","journal-title":"Biophys. J."},{"key":"2021042013310613600_bib76","first-page":"1168","article-title":"The Drosophila Pkn protein kinase is a Rho\/Rac effector target required for dorsal closure during embryogenesis","volume-title":"Genes Dev."},{"key":"2021042013310613600_bib77","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.ydbio.2013.10.005","article-title":"Cellular mechanics of germ band retraction in Drosophila.","volume":"384","author":"Lynch","year":"2013","journal-title":"Dev. Biol."},{"key":"2021042013310613600_bib78","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1016\/0092-8674(86)90515-5","article-title":"Isolation, structure, and expression of even-skipped: a second pair-rule gene of Drosophila containing a homeo box.","volume":"47","author":"Macdonald","year":"1986","journal-title":"Cell"},{"key":"2021042013310613600_bib79","doi-asserted-by":"publisher","first-page":"3951","DOI":"10.1242\/dev.068346","article-title":"The regulation of Hox gene expression during animal development.","volume":"140","author":"Mallo","year":"2013","journal-title":"Development"},{"key":"2021042013310613600_bib80","doi-asserted-by":"publisher","first-page":"R216","DOI":"10.1186\/gb-2007-8-10-r216","article-title":"The ribosomal protein genes and Minute loci of Drosophila melanogaster.","volume":"8","author":"Marygold","year":"2007","journal-title":"Genome Biol."},{"key":"2021042013310613600_bib81","doi-asserted-by":"publisher","first-page":"e27159","DOI":"10.1371\/journal.pone.0027159","article-title":"Patterned Cell Adhesion Associated with Tissue Deformations during Dorsal Closure in Drosophila.","volume":"6","author":"Mateus","year":"2011","journal-title":"PLoS One"},{"key":"2021042013310613600_bib82","doi-asserted-by":"crossref","first-page":"3607","DOI":"10.1242\/dev.127.16.3607","article-title":"The canonical Wg and JNK signaling cascades collaborate to promote both dorsal closure and ventral patterning.","volume":"127","author":"McEwen","year":"2000","journal-title":"Development"},{"key":"2021042013310613600_bib83","doi-asserted-by":"publisher","first-page":"R562","DOI":"10.1016\/S0960-9822(00)00611-4","article-title":"Wnt signaling: Moving in a new direction.","volume":"10","author":"McEwen","year":"2000","journal-title":"Curr. Biol."},{"key":"2021042013310613600_bib84","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1242\/dev.014001","article-title":"Dynamic analysis of filopodial interactions during the zippering phase of Drosophila dorsal closure.","volume":"135","author":"Millard","year":"2008","journal-title":"Development"},{"key":"2021042013310613600_bib85","doi-asserted-by":"publisher","first-page":"3273","DOI":"10.1242\/dev.01217","article-title":"Armadillo\/beta-catenin-dependent Wnt signalling is required for the polarisation of epidermal cells during dorsal closure in Drosophila.","volume":"131","author":"Morel","year":"2004","journal-title":"Development"},{"key":"2021042013310613600_bib86","doi-asserted-by":"publisher","first-page":"3043","DOI":"10.1242\/dev.060731","article-title":"Spatial, temporal and molecular hierarchies in the link between death, delamination and dorsal closure.","volume":"138","author":"Muliyil","year":"2011","journal-title":"Development"},{"key":"2021042013310613600_bib87","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/j.devcel.2013.12.019","article-title":"Mitochondrial ROS regulates cytoskeletal and mitochondrial remodeling to tune cell and tissue dynamics in a model for wound healing.","volume":"28","author":"Muliyil","year":"2014","journal-title":"Dev. Cell"},{"key":"2021042013310613600_bib88","doi-asserted-by":"publisher","first-page":"609","DOI":"10.2174\/138920212803759721","article-title":"Planar cell polarity signaling in collective cell movements during morphogenesis and disease.","volume":"13","author":"Munoz-Soriano","year":"2012","journal-title":"Curr. Genomics"},{"key":"2021042013310613600_bib89","doi-asserted-by":"publisher","first-page":"3063","DOI":"10.1242\/dev.02467","article-title":"The Fes\/Fer non-receptor tyrosine kinase cooperates with Src42A to regulate dorsal closure in Drosophila.","volume":"133","author":"Murray","year":"2006","journal-title":"Development"},{"key":"2021042013310613600_bib90","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.cub.2004.02.033","article-title":"Novel functions for integrins in epithelial morphogenesis.","volume":"14","author":"Narasimha","year":"2004","journal-title":"Curr. Biol."},{"key":"2021042013310613600_bib91","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1007\/BF00268085","article-title":"Genetic Control of the Cell Division Cycle in the Fission Yeast Schizosaccharomyces pombe.","volume":"146","author":"Nurse","year":"1976","journal-title":"Mol. Gen. Genet."},{"key":"2021042013310613600_bib92","doi-asserted-by":"publisher","first-page":"1675","DOI":"10.1126\/science.3686007","article-title":"Determination of anteroposterior polarity in Drosophila.","volume":"238","author":"Nusslein-Volhard","year":"1987","journal-title":"Science"},{"key":"2021042013310613600_bib93","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1038\/287795a0","article-title":"Mutations affecting segment number and polarity in Drosophila.","volume":"287","author":"N\u00fcsslein-Volhard","year":"1980","journal-title":"Nature"},{"key":"2021042013310613600_bib94","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1007\/BF00848156","article-title":"Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster: I. Zygotic loci on the second chromosome.","volume":"193","author":"N\u00fcsslein-Volhard","year":"1984","journal-title":"Wilehm Roux Arch. Dev. Biol."},{"key":"2021042013310613600_bib95","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1242\/jcs.114.3.493","article-title":"Real-time imaging of cell-cell adherens junctions reveals that Drosophila mesoderm invagination begins with two phases of apical constriction of cells.","volume":"114","author":"Oda","year":"2001","journal-title":"J. Cell Sci."},{"key":"2021042013310613600_bib96","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1002\/bdra.23072","article-title":"Epithelial fusion during neural tube morphogenesis.","volume":"94","author":"Pai","year":"2012","journal-title":"Birth Defects Res. A Clin. Mol. Teratol."},{"key":"2021042013310613600_bib97","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1242\/jcs.01663","article-title":"Epithelial re-organization and dynamics of progression through mitosis in Drosophila separase complex mutants.","volume":"118","author":"Pandey","year":"2005","journal-title":"J. Cell Sci."},{"key":"2021042013310613600_bib98","doi-asserted-by":"publisher","first-page":"1161","DOI":"10.1038\/ncb3420","article-title":"Amnioserosa cell constriction but not epidermal actin cable tension autonomously drives dorsal closure.","volume":"18","author":"Pasakarnis","year":"2016","journal-title":"Nat. Cell Biol."},{"key":"2021042013310613600_bib99","doi-asserted-by":"publisher","first-page":"2583","DOI":"10.1529\/biophysj.106.094110","article-title":"Upregulation of forces and morphogenic asymmetries in dorsal closure during Drosophila development.","volume":"92","author":"Peralta","year":"2007","journal-title":"Biophys. J."},{"key":"2021042013310613600_bib100","doi-asserted-by":"publisher","first-page":"015004","DOI":"10.1088\/1478-3975\/5\/1\/015004","article-title":"Emergent properties during dorsal closure in Drosophila morphogenesis.","volume":"5","author":"Peralta","year":"2008","journal-title":"Phys. Biol."},{"key":"2021042013310613600_bib101","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/0968-0004(94)90140-6","article-title":"Signal transduction in the early Drosophila embryo: when genetics meets biochemistry.","volume":"19","author":"Perrimon","year":"1994","journal-title":"Trends Biochem. Sci."},{"key":"2021042013310613600_bib102","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1242\/jcs.106.1.87","article-title":"Mutations in the Drosophila melanogaster gene three rows permit aspects of mitosis to continue in the absence of chromatid segregation.","volume":"106","author":"Philp","year":"1993","journal-title":"J. Cell Sci."},{"key":"2021042013310613600_bib103","doi-asserted-by":"publisher","first-page":"2227","DOI":"10.1242\/dev.019802","article-title":"Control of cell flattening and junctional remodeling during squamous epithelial morphogenesis in Drosophila.","volume":"135","author":"Pope","year":"2008","journal-title":"Development"},{"key":"2021042013310613600_bib104","doi-asserted-by":"publisher","first-page":"1701","DOI":"10.1242\/dev.068338","article-title":"Mechanisms of tissue fusion during development.","volume":"139","author":"Ray","year":"2012","journal-title":"Development"},{"key":"2021042013310613600_bib105","doi-asserted-by":"publisher","first-page":"1814","DOI":"10.1242\/dev.107045","article-title":"Recapitulation of morphogenetic cell shape changes enables wound re-epithelialisation.","volume":"141","author":"Razzell","year":"2014","journal-title":"Development"},{"key":"2021042013310613600_bib106","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/j.cub.2004.02.029","article-title":"Integrin-dependent apposition of Drosophila extraembryonic membranes promotes morphogenesis and prevents anoikis.","volume":"14","author":"Reed","year":"2004","journal-title":"Curr. Biol."},{"key":"2021042013310613600_bib107","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1126\/science.278.5338.669","article-title":"Common and distinct roles of DFos and DJun during Drosophila development.","volume":"278","author":"Riesgo-Escovar","year":"1997","journal-title":"Science"},{"key":"2021042013310613600_bib147","doi-asserted-by":"publisher","first-page":"e1004927","DOI":"10.1371\/journal.pgen.1004927","article-title":"acal is a long non-coding RNA in JNK signaling in epithelial shape changes during drosophila dorsal closure.","volume":"11","author":"R\u00edos-Barrera","year":"2015","journal-title":"PLoS Genet."},{"key":"2021042013310613600_bib108","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1002\/dvg.22354","article-title":"Regulating cell morphogenesis: the Drosophila Jun N-terminal kinase pathway.","volume":"51","author":"R\u00edos-Barrera","year":"2013","journal-title":"Genesis"},{"key":"2021042013310613600_bib109","doi-asserted-by":"publisher","first-page":"220","DOI":"10.2976\/1.2955565","article-title":"Actomyosin purse strings: renewable resources that make morphogenesis robust and resilient.","volume":"2","author":"Rodriguez-Diaz","year":"2008","journal-title":"HFSP J."},{"key":"2021042013310613600_bib110","doi-asserted-by":"publisher","first-page":"2177","DOI":"10.1242\/dev.050781","article-title":"The Drosophila serine protease homologue Scarface regulates JNK signalling in a negative-feedback loop during epithelial morphogenesis.","volume":"137","author":"Rousset","year":"2010","journal-title":"Development"},{"key":"2021042013310613600_bib111","doi-asserted-by":"publisher","first-page":"e1006640","DOI":"10.1371\/journal.pgen.1006640","article-title":"Signalling crosstalk at the leading edge controls tissue closure dynamics in the Drosophila embryo.","volume":"13","author":"Rousset","year":"2017","journal-title":"PLoS Genet."},{"key":"2021042013310613600_bib112","doi-asserted-by":"crossref","first-page":"3575","DOI":"10.1242\/dev.129.15.3575","article-title":"The role of TGF beta signaling in the formation of the dorsal nervous system is conserved between Drosophila and chordates.","volume":"129","author":"Rusten","year":"2002","journal-title":"Development"},{"key":"2021042013310613600_bib113","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1016\/j.devcel.2015.03.016","article-title":"Decrease in Cell Volume Generates Contractile Forces Driving Dorsal Closure.","volume":"33","author":"Saias","year":"2015","journal-title":"Dev. Cell"},{"key":"2021042013310613600_bib114","doi-asserted-by":"publisher","first-page":"2350","DOI":"10.1091\/mbc.e12-12-0868","article-title":"Local, cell-nonautonomous feedback regulation of myosin dynamics patterns transitions in cell behavior: a role for tension and geometry?","volume":"24","author":"Saravanan","year":"2013","journal-title":"Mol. Biol. Cell"},{"key":"2021042013310613600_bib115","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1038\/nmeth.2089","article-title":"NIH Image to ImageJ: 25 years of image analysis.","volume":"9","author":"Schneider","year":"2012","journal-title":"Nat. Methods"},{"key":"2021042013310613600_bib116","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1006\/dbio.2002.0698","article-title":"Cellular processes associated with germ band retraction in Drosophila.","volume":"248","author":"Sch\u00f6ck","year":"2002","journal-title":"Dev. Biol."},{"key":"2021042013310613600_bib117","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1016\/0012-1606(86)90179-X","article-title":"Germline Autonomy of Maternal-Effect Mutations Altering the Embryonic Body Pattern of Drosophila.","volume":"113","author":"Schupbach","year":"1986","journal-title":"Dev. Biol."},{"key":"2021042013310613600_bib118","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1007\/BF00376063","article-title":"Maternal-effect mutations altering the anterior-posterior pattern of the Drosophila embryo.","volume":"195","author":"Sch\u00fcpbach","year":"1986","journal-title":"Roux Arch. Dev. Biol."},{"key":"2021042013310613600_bib119","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1093\/genetics\/121.1.101","article-title":"Female Sterile Mutations on the Second Chromosome of Drosophila melanogaster. I. Maternal Effect Mutations.","volume":"121","author":"Schupbach","year":"1989","journal-title":"Genetics"},{"key":"2021042013310613600_bib120","doi-asserted-by":"publisher","first-page":"e60180","DOI":"10.1371\/journal.pone.0060180","article-title":"Modulation of morphogenesis by Egfr during dorsal closure in Drosophila.","volume":"8","author":"Shen","year":"2013","journal-title":"PLoS One"},{"key":"2021042013310613600_bib121","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1016\/j.bpj.2012.01.027","article-title":"Cell ingression and apical shape oscillations during dorsal closure in Drosophila.","volume":"102","author":"Sokolow","year":"2012","journal-title":"Biophys. J."},{"key":"2021042013310613600_bib122","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1016\/j.cell.2009.03.050","article-title":"Pulsed forces timed by a ratchet-like mechanism drive directed tissue movement during dorsal closure.","volume":"137","author":"Solon","year":"2009","journal-title":"Cell"},{"key":"2021042013310613600_bib123","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/S1534-5807(02)00402-1","article-title":"A RhoGEF and Rho family GTPase-activating protein complex links the contractile ring to cortical microtubules at the onset of cytokinesis.","volume":"4","author":"Somers","year":"2003","journal-title":"Dev. Cell"},{"key":"2021042013310613600_bib124","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.devcel.2014.07.027","article-title":"Combining genetic perturbations and proteomics to examine kinase-phosphatase networks in Drosophila embryos.","volume":"31","author":"Sopko","year":"2014","journal-title":"Dev. Cell"},{"key":"2021042013310613600_bib125","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1038\/embor.2010.43","article-title":"Scarface, a secreted serine protease-like protein, regulates polarized localization of laminin A at the basement membrane of the Drosophila embryo.","volume":"11","author":"Sorrosal","year":"2010","journal-title":"EMBO Rep."},{"key":"2021042013310613600_bib126","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/0012-1606(69)90052-9","article-title":"The precardiac areas and formation of the tubular heart in the chick embryo.","volume":"19","author":"Stalsberg","year":"1969","journal-title":"Dev. Biol."},{"key":"2021042013310613600_bib127","doi-asserted-by":"crossref","first-page":"3241","DOI":"10.1242\/dev.126.14.3241","article-title":"The Drosophila homeobox genes zfh-1 and even-skipped are required for cardiac-specific differentiation of a numb-dependent lineage decision.","volume":"126","author":"Su","year":"1999","journal-title":"Development"},{"key":"2021042013310613600_bib128","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1242\/jcs.193003","article-title":"The spectraplakin Short stop is an essential microtubule regulator involved in epithelial closure in Drosophila.","volume":"130","author":"Tak\u00e1cs","year":"2017","journal-title":"J. Cell Sci."},{"key":"2021042013310613600_bib129","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1126\/science.287.5451.324","article-title":"Regulation of JNK by Src during Drosophila development.","volume":"287","author":"Tateno","year":"2000","journal-title":"Science"},{"key":"2021042013310613600_bib130","doi-asserted-by":"publisher","first-page":"1683","DOI":"10.1126\/science.1157052","article-title":"Apoptotic force and tissue dynamics during Drosophila embryogenesis.","volume":"321","author":"Toyama","year":"2008","journal-title":"Science"},{"key":"2021042013310613600_bib131","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1002\/dvdy.21405","article-title":"Head involution in Drosophila: genetic and morphogenetic connections to dorsal closure.","volume":"237","author":"VanHook","year":"2008","journal-title":"Dev. Dyn."},{"key":"2021042013310613600_bib132","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/j.ydbio.2006.09.020","article-title":"Specialized extraembryonic cells connect embryonic and extraembryonic epidermis in response to Dpp during dorsal closure in Drosophila.","volume":"301","author":"Wada","year":"2007","journal-title":"Dev. Biol."},{"key":"2021042013310613600_bib133","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/S0092-8674(01)00540-2","article-title":"Jelly belly: a Drosophila LDL receptor repeat-containing signal required for mesoderm migration and differentiation.","volume":"107","author":"Weiss","year":"2001","journal-title":"Cell"},{"key":"2021042013310613600_bib134","doi-asserted-by":"publisher","first-page":"3552","DOI":"10.1091\/mbc.e14-07-1190","article-title":"Complete canthi removal reveals that forces from the amnioserosa alone are sufficient to drive dorsal closure in Drosophila.","volume":"25","author":"Wells","year":"2014","journal-title":"Mol. Biol. Cell"},{"key":"2021042013310613600_bib135","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1007\/BF00848158","article-title":"Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster: III. Zygotic loci on the X-chromosome and fourth chromosome.","volume":"193","author":"Wieschaus","year":"1984","journal-title":"Wilehm Roux Arch. Dev. Biol."},{"key":"2021042013310613600_bib136","first-page":"29","article-title":"Genetic Control of Bacteriophage T4 Morphogenesis.","volume":"31","author":"Wood","year":"1973","journal-title":"Symp. Soc. Dev. Biol."},{"key":"2021042013310613600_bib137","first-page":"1160","article-title":"Bacteriophage Assembly.","volume":"27","author":"Wood","year":"1968","journal-title":"Fed. Proc."},{"key":"2021042013310613600_bib138","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/j.devcel.2017.01.001","article-title":"Macrophage Functions in Tissue Patterning and Disease: New Insights from the Fly.","volume":"40","author":"Wood","year":"2017","journal-title":"Dev. Cell"},{"key":"2021042013310613600_bib139","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.ydbio.2005.03.005","article-title":"The small GTPase Rac plays multiple roles in epithelial sheet fusion\u2013dynamic studies of Drosophila dorsal closure.","volume":"282","author":"Woolner","year":"2005","journal-title":"Dev. Biol."},{"key":"2021042013310613600_bib140","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1016\/j.devcel.2008.10.001","article-title":"Heterotrimeric G proteins regulate a noncanonical function of septate junction proteins to maintain cardiac integrity in Drosophila.","volume":"15","author":"Yi","year":"2008","journal-title":"Dev. Cell"},{"key":"2021042013310613600_bib141","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1101\/gad.7.1.29","article-title":"Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function.","volume":"7","author":"Young","year":"1993","journal-title":"Genes Dev."},{"key":"2021042013310613600_bib142","doi-asserted-by":"publisher","first-page":"2936","DOI":"10.1002\/dvdy.21722","article-title":"Leading edge-secreted Dpp cooperates with ACK-dependent signaling from the amnioserosa to regulate myosin levels during dorsal closure.","volume":"237","author":"Zahedi","year":"2008","journal-title":"Dev. Dyn."},{"key":"2021042013310613600_bib143","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/S1534-5807(04)00060-7","article-title":"Patterned gene expression directs bipolar planar polarity in Drosophila.","volume":"6","author":"Zallen","year":"2004","journal-title":"Dev. Cell"},{"key":"2021042013310613600_bib144","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1016\/S1673-8527(09)60080-1","article-title":"POSH is involved in Eiger-Basket (TNF-JNK) signaling and embryogenesis in Drosophila.","volume":"37","author":"Zhang","year":"2010","journal-title":"J. Genet. Genomics"}],"container-title":["G3 Genes|Genomes|Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/g3journal\/article-pdf\/8\/7\/2361\/37189567\/g3journal2361.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/g3journal\/article-pdf\/8\/7\/2361\/37189567\/g3journal2361.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T16:42:07Z","timestamp":1751647327000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/g3journal\/article\/8\/7\/2361\/6027090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,1]]},"references-count":146,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,7,1]]}},"URL":"https:\/\/doi.org\/10.1534\/g3.118.200233","relation":{},"ISSN":["2160-1836"],"issn-type":[{"value":"2160-1836","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,7,1]]},"published":{"date-parts":[[2018,7,1]]}}}