{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T14:13:07Z","timestamp":1780582387051,"version":"3.54.1"},"reference-count":43,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2007,4,1]],"date-time":"2007-04-01T00:00:00Z","timestamp":1175385600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>As a major agent of rapid speciation, interspecific hybridization has played an important role in plant evolution. When hybridization involves species that exhibit self-incompatibility (SI), this prezygotic barrier to self-fertilization must be overcome or lost to allow selfing. How SI, a normally dominant trait, is lost in nascent hybrids is not known, however. Here we demonstrate that hybrid self-fertility can result from epigenetic changes in expression of the S-locus genes that determine specificity in the SI response. We analyzed loss of SI in synthetic hybrids produced by crossing self-fertile and self-incompatible species in each of two crucifer genera. We show that SI is lost in the stigmas of A. thaliana\u2013lyrata hybrids and their neo-allotetraploid derivatives and in the pollen of C. rubella\u2013grandiflora hybrids and their homoploid progenies. Aberrant processing of S-locus receptor kinase gene transcripts as detected in Arabidopsis hybrids and suppression of the S-locus cysteine-rich protein gene as observed in Capsella hybrids are two reversible mechanisms by which SI might break down upon interspecific hybridization to generate self-fertile hybrids in nature.<\/jats:p>","DOI":"10.1534\/genetics.106.069393","type":"journal-article","created":{"date-parts":[[2007,1,22]],"date-time":"2007-01-22T01:58:00Z","timestamp":1169431080000},"page":"1965-1973","source":"Crossref","is-referenced-by-count":69,"title":["Epigenetic Mechanisms for Breakdown of Self-Incompatibility in Interspecific Hybrids"],"prefix":"10.1093","volume":"175","author":[{"given":"June B","family":"Nasrallah","sequence":"first","affiliation":[{"name":"Department of Plant Biology , Cornell University, Ithaca, New York 14853 and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Plant Biology , Cornell University, Ithaca, New York 14853 and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Sherman-Broyles","sequence":"additional","affiliation":[{"name":"Department of Plant Biology , Cornell University, Ithaca, New York 14853 and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renate","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) , D-06466 Gatersleben, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikhail E","family":"Nasrallah","sequence":"additional","affiliation":[{"name":"Department of Plant Biology , Cornell University, Ithaca, New York 14853 and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2007,4,1]]},"reference":[{"key":"2023030305334472100_","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1046\/j.1365-313x.2000.00790.x","volume":"23","year":"2000","journal-title":"Plant J."},{"key":"2023030305334472100_","year":"1997"},{"key":"2023030305334472100_","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/hdy.1955.2","volume":"9","year":"1955","journal-title":"III. 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