{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T09:42:12Z","timestamp":1788169332493,"version":"build-2803163510"},"reference-count":105,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Fish are known for the outstanding variety of their sex determination mechanisms and sex chromosome systems. The western (Gambusia affinis) and eastern mosquitofish (G. holbrooki) are sister species for which different sex determination mechanisms have been described: ZZ\/ZW for G. affinis and XX\/XY for G. holbrooki. Here, we carried out restriction-site associated DNA (RAD-) and pool sequencing (Pool-seq) to characterize the sex chromosomes of both species. We found that the ZW chromosomes of G. affinis females and the XY chromosomes of G. holbrooki males correspond to different linkage groups, and thus evolved independently from separate autosomes. In interspecific hybrids, the Y chromosome is dominant over the W chromosome, and X is dominant over Z. In G. holbrooki, we identified a candidate region for the Y-linked melanic pigmentation locus, a rare male phenotype that constitutes a potentially sexually antagonistic trait and is associated with other such characteristics, e.g., large body size and aggressive behavior. We developed a SNP-based marker in the Y-linked allele of GIPC PDZ domain containing family member 1 (gipc1), which was linked to melanism in all tested G. holbrooki populations. This locus represents an example for a color locus that is located in close proximity to a putative sex determiner, and most likely substantially contributed to the evolution of the Y.<\/jats:p>","DOI":"10.1534\/genetics.119.302698","type":"journal-article","created":{"date-parts":[[2019,11,9]],"date-time":"2019-11-09T03:39:11Z","timestamp":1573270751000},"page":"193-209","source":"Crossref","is-referenced-by-count":43,"title":["Independent Origin of XY and ZW Sex Determination Mechanisms in Mosquitofish Sister Species"],"prefix":"10.1093","volume":"214","author":[{"given":"Verena A","family":"Kottler","sequence":"first","affiliation":[{"name":"Physiological Chemistry, Biocenter, University of Wuerzburg, 97074, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Feron","sequence":"additional","affiliation":[{"name":"INRA, UR1037 Fish Physiology and Genomics, 35000 Rennes, France"},{"name":"University of Lausanne and Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Indrajit","family":"Nanda","sequence":"additional","affiliation":[{"name":"Institute for Human Genetics, Biocenter, University of Wuerzburg, 97074, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Klopp","sequence":"additional","affiliation":[{"name":"Sigenae, Math\u00e9matiques et Informatique Appliqu\u00e9es de Toulouse, INRA, 31326 Castanet Tolosan, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang","family":"Du","sequence":"additional","affiliation":[{"name":"Physiological Chemistry, Biocenter, University of Wuerzburg, 97074, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Kneitz","sequence":"additional","affiliation":[{"name":"Physiological Chemistry, Biocenter, University of Wuerzburg, 97074, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederik","family":"Helmprobst","sequence":"additional","affiliation":[{"name":"Physiological Chemistry, Biocenter, University of Wuerzburg, 97074, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dunja K","family":"Lamatsch","sequence":"additional","affiliation":[{"name":"University of Innsbruck, Research Department for Limnology, Mondsee, 5310 Mondsee, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9line","family":"Lopez-Roques","sequence":"additional","affiliation":[{"name":"INRA, US 1426, GeT-PlaGe, Genotoul, 31326 Castanet-Tolosan, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jer\u00f4me","family":"Lluch","sequence":"additional","affiliation":[{"name":"INRA, US 1426, GeT-PlaGe, Genotoul, 31326 Castanet-Tolosan, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Journot","sequence":"additional","affiliation":[{"name":"Montpellier GenomiX (MGX), University Montpellier, CNRS, INSERM, 34094 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugues","family":"Parrinello","sequence":"additional","affiliation":[{"name":"Montpellier GenomiX (MGX), University Montpellier, CNRS, INSERM, 34094 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yann","family":"Guiguen","sequence":"additional","affiliation":[{"name":"INRA, UR1037 Fish Physiology and Genomics, 35000 Rennes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manfred","family":"Schartl","sequence":"additional","affiliation":[{"name":"Physiological Chemistry, Biocenter, University of Wuerzburg, 97074, Germany"},{"name":"Developmental Biochemistry, Biocenter, University of Wuerzburg, 97074, Germany"},{"name":"Hagler Institute for Advanced Study and Department of Biology, Texas A&M University, College Station, Texas 77843"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,1,1]]},"reference":[{"key":"2022011123503714800_bib1","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","article-title":"Basic local alignment search tool.","volume":"215","author":"Altschul","year":"1990","journal-title":"J. Mol. Biol."},{"key":"2022011123503714800_bib2","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1534\/genetics.111.127324","article-title":"Genome evolution and meiotic maps by massively parallel DNA sequencing: spotted gar, an outgroup for the teleost genome duplication.","volume":"188","author":"Amores","year":"2011","journal-title":"Genetics"},{"key":"2022011123503714800_bib3","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1093\/oxfordjournals.jhered.a110880","article-title":"Inheritance of melanistic pigmentation in the eastern mosquitofish.","volume":"80","author":"Angus","year":"1989","journal-title":"J. Hered."},{"key":"2022011123503714800_bib4","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1038\/8792","article-title":"Sox9 is required for cartilage formation.","volume":"22","author":"Bi","year":"1999","journal-title":"Nat. Genet."},{"key":"2022011123503714800_bib5","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1023\/A:1001914208075","article-title":"Variation of female preference for male coloration in the eastern mosquitofish Gambusia holbrooki.","volume":"30","author":"Bisazza","year":"2000","journal-title":"Behav. Genet."},{"key":"2022011123503714800_bib6","doi-asserted-by":"publisher","first-page":"509","DOI":"10.2307\/1443231","article-title":"The North American mosquitofish, Gambusia affinis: a unique case in sex chromosome evolution.","volume":"1979","author":"Black","year":"1979","journal-title":"Copeia"},{"key":"2022011123503714800_bib7","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1111\/j.1755-148X.2009.00614.x","article-title":"Pigmentary function and evolution of tyrp1 gene duplicates in fish.","volume":"22","author":"Braasch","year":"2009","journal-title":"Pigment Cell Melanoma Res."},{"key":"2022011123503714800_bib8","doi-asserted-by":"publisher","first-page":"6519","DOI":"10.1523\/JNEUROSCI.19-15-06519.1999","article-title":"Cloning and characterization of neuropilin-1-interacting protein: a PSD-95\/Dlg\/ZO-1 domain-containing protein that interacts with the cytoplasmic domain of neuropilin-1.","volume":"19","author":"Cai","year":"1999","journal-title":"J. Neurosci."},{"key":"2022011123503714800_bib9","doi-asserted-by":"publisher","first-page":"566","DOI":"10.2307\/1442462","article-title":"Cytomorphology of six species of gambusiine fishes.","volume":"1971","author":"Campos","year":"1971","journal-title":"Copeia"},{"key":"2022011123503714800_bib10","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1038\/nrg.2017.60","article-title":"Vertebrate sex determination: evolutionary plasticity of a fundamental switch.","volume":"18","author":"Capel","year":"2017","journal-title":"Nat. Rev. Genet."},{"key":"2022011123503714800_bib11","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1534\/g3.111.000240","article-title":"Stacks: building and genotyping Loci de novo from short-read sequences.","volume":"1","author":"Catchen","year":"2011","journal-title":"G3 (Bethesda)"},{"key":"2022011123503714800_bib12","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1016\/j.devcel.2006.03.012","article-title":"Selective regulation of arterial branching morphogenesis by synectin.","volume":"10","author":"Chittenden","year":"2006","journal-title":"Dev. Cell"},{"key":"2022011123503714800_bib13","doi-asserted-by":"publisher","first-page":"2166","DOI":"10.1111\/evo.12099","article-title":"Phylogenomics reveals extensive reticulate evolution in Xiphophorus fishes.","volume":"67","author":"Cui","year":"2013","journal-title":"Evolution"},{"key":"2022011123503714800_bib14","doi-asserted-by":"publisher","first-page":"12340","DOI":"10.1073\/pnas.95.21.12340","article-title":"GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP.","volume":"95","author":"De Vries","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2022011123503714800_bib15","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/S0044-8486(02)00057-1","article-title":"Sex determination and sex differentiation in fish: an overview of genetic, physiological, and environmental influences.","volume":"208","author":"Devlin","year":"2002","journal-title":"Aquaculture"},{"key":"2022011123503714800_bib16","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1093\/molbev\/msy181","article-title":"The origin of a new sex chromosome by introgression between two stickleback fishes.","volume":"36","author":"Dixon","year":"2018","journal-title":"Mol. Biol. Evol."},{"key":"2022011123503714800_bib17","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1186\/1471-2164-15-774","article-title":"Identification of male-specific amh duplication, sexually differentially expressed genes and microRNAs at early embryonic development of Nile tilapia (Oreochromis niloticus).","volume":"15","author":"Eshel","year":"2014","journal-title":"BMC Genomics"},{"key":"2022011123503714800_bib18","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1034\/j.1600-0749.2000.130502.x","article-title":"The regulation of motile activity in fish chromatophores.","volume":"13","author":"Fujii","year":"2000","journal-title":"Pigment Cell Res."},{"key":"2022011123503714800_bib19","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.1126\/science.aas9408","article-title":"Sex reversal following deletion of a single distal enhancer of Sox9.","volume":"360","author":"Gonen","year":"2018","journal-title":"Science"},{"key":"2022011123503714800_bib20","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1093\/molbev\/mst012","article-title":"Building phylogenetic trees from molecular data with MEGA.","volume":"30","author":"Hall","year":"2013","journal-title":"Mol. Biol. Evol."},{"key":"2022011123503714800_bib21","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1007\/s00442-002-0968-7","article-title":"The role of introduced mosquitofish (Gambusia holbrooki) in excluding the native green and golden bell frog (Litoria aurea) from original habitats in south-eastern Australia.","volume":"132","author":"Hamer","year":"2002","journal-title":"Oecologia"},{"key":"2022011123503714800_bib22","doi-asserted-by":"publisher","first-page":"11271","DOI":"10.1038\/ncomms11271","article-title":"Viviparity stimulates diversification in an order of fish.","volume":"7","author":"Helmstetter","year":"2016","journal-title":"Nat. Commun."},{"key":"2022011123503714800_bib23","doi-asserted-by":"publisher","first-page":"1260","DOI":"10.15252\/embr.201540667","article-title":"Plasticity of gene-regulatory networks controlling sex determination: of masters, slaves, usual suspects, newcomers, and usurpators.","volume":"16","author":"Herpin","year":"2015","journal-title":"EMBO Rep."},{"key":"2022011123503714800_bib24","doi-asserted-by":"publisher","first-page":"1855","DOI":"10.1534\/g3.118.200101","article-title":"A high-quality reference genome for the invasive mosquitofish Gambusia affinis using a Chicago library.","volume":"8","author":"Hoffberg","year":"2018","journal-title":"G3 (Bethesda)"},{"key":"2022011123503714800_bib25","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1098\/rspb.2003.2348","article-title":"Melanic body colour and aggressive mating behaviour are correlated traits in male mosquitofish (Gambusia holbrooki).","volume":"270","author":"Horth","year":"2003","journal-title":"Proc. Biol. Sci."},{"key":"2022011123503714800_bib26","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1111\/j.1420-9101.2004.00710.x","article-title":"Predation and the persistence of melanic male mosquitofish (Gambusia holbrooki).","volume":"17","author":"Horth","year":"2004","journal-title":"J. Evol. Biol."},{"key":"2022011123503714800_bib27","doi-asserted-by":"publisher","first-page":"4938","DOI":"10.1242\/jeb.02599","article-title":"A sex-linked allele, autosomal modifiers and temperature-dependence appear to regulate melanism in male mosquitofish (Gambusia holbrooki).","volume":"209","author":"Horth","year":"2006","journal-title":"J. Exp. Biol."},{"key":"2022011123503714800_bib28","doi-asserted-by":"publisher","first-page":"2239","DOI":"10.1098\/rspb.2002.2143","article-title":"Frequency-dependent numerical dynamics in mosquitofish.","volume":"269","author":"Horth","year":"2002","journal-title":"Proc. Biol. Sci."},{"key":"2022011123503714800_bib29","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1643\/CG-09-044","article-title":"Color, body size, and genitalia size are correlated traits in eastern mosquitofish (Gambusia holbrooki).","volume":"2010","author":"Horth","year":"2010","journal-title":"Copeia"},{"key":"2022011123503714800_bib30","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1016\/j.ympev.2006.06.009","article-title":"A phylogenetic and biogeographic perspective on the evolution of poeciliid fishes.","volume":"43","author":"Hrbek","year":"2007","journal-title":"Mol. Phylogenet. Evol."},{"key":"2022011123503714800_bib31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2307\/2411933","article-title":"Hybridization between fish species in nature.","volume":"4","author":"Hubbs","year":"1955","journal-title":"Syst. Zool."},{"key":"2022011123503714800_bib32","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/j.gendis.2014.09.004","article-title":"The versatile functions of Sox9 in development, stem cells, and human diseases.","volume":"1","author":"Jo","year":"2014","journal-title":"Genes Dis."},{"key":"2022011123503714800_bib33","first-page":"19","article-title":"The sex-determining mechanism of the platyfish, Xiphophorus maculatus","author":"Kallman","year":"1973"},{"key":"2022011123503714800_bib34","first-page":"81","article-title":"The platyfish, Xiphophorus maculatus","author":"Kallman","year":"1975"},{"key":"2022011123503714800_bib35","first-page":"95","article-title":"A new look at sex determination in poeciliid fishes","author":"Kallman","year":"1984"},{"key":"2022011123503714800_bib36","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1002798","article-title":"A trans-species missense SNP in Amhr2 is associated with sex determination in the tiger pufferfish, Takifugu rubripes (fugu).","volume":"8","author":"Kamiya","year":"2012","journal-title":"PLoS Genet."},{"key":"2022011123503714800_bib37","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/1471-2148-13-25","article-title":"Comprehensive phylogenetic analysis of all species of swordtails and platies (Pisces: genus Xiphophorus) uncovers a hybrid origin of a swordtail fish, Xiphophorus monticolus, and demonstrates that the sexually selected sword originated in the ancestral lineage of the genus, but was lost again secondarily.","volume":"13","author":"Kang","year":"2013","journal-title":"BMC Evol. Biol."},{"key":"2022011123503714800_bib38","doi-asserted-by":"publisher","DOI":"10.1038\/emm.2013.49","article-title":"Functional proteomics, human genetics and cancer biology of GIPC family members.","volume":"45","author":"Katoh","year":"2013","journal-title":"Exp. Mol. Med."},{"key":"2022011123503714800_bib39","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1002\/dvdy.23927","article-title":"Novel sex-determining genes in fish and sex chromosome evolution.","volume":"242","author":"Kikuchi","year":"2013","journal-title":"Dev. Dyn."},{"key":"2022011123503714800_bib40","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1038\/nature08441","article-title":"A role for a neo-sex chromosome in stickleback speciation.","volume":"461","author":"Kitano","year":"2009","journal-title":"Nature"},{"key":"2022011123503714800_bib41","doi-asserted-by":"publisher","first-page":"3435","DOI":"10.1093\/bioinformatics\/btr589","article-title":"PoPoolation2: identifying differentiation between populations using sequencing of pooled DNA samples (Pool-Seq).","volume":"27","author":"Kofler","year":"2011","journal-title":"Bioinformatics"},{"key":"2022011123503714800_bib42","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1101\/gr.5016106","article-title":"Genomic organization of the sex-determining and adjacent regions of the sex chromosomes of medaka.","volume":"16","author":"Kondo","year":"2006","journal-title":"Genome Res."},{"key":"2022011123503714800_bib43","doi-asserted-by":"publisher","DOI":"10.3390\/genes9050233","article-title":"The colorful sex chromosomes of teleost fish.","volume":"9","author":"Kottler","year":"2018","journal-title":"Genes (Basel)"},{"key":"2022011123503714800_bib44","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0085647","article-title":"Multiple pigment cell types contribute to the black, blue, and orange ornaments of male guppies (Poecilia reticulata).","volume":"9","author":"Kottler","year":"2014","journal-title":"PLoS One"},{"key":"2022011123503714800_bib45","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1111\/pcmr.12272","article-title":"A dominant mutation in tyrp1A leads to melanophore death in zebrafish.","volume":"27","author":"Krauss","year":"2014","journal-title":"Pigment Cell Melanoma Res."},{"key":"2022011123503714800_bib46","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1093\/molbev\/msy096","article-title":"Mega X: molecular evolutionary genetics analysis across computing platforms.","volume":"35","author":"Kumar","year":"2018","journal-title":"Mol. Biol. Evol."},{"key":"2022011123503714800_bib47","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0118214","article-title":"A transcriptome derived female-specific marker from the invasive Western mosquitofish (Gambusia affinis).","volume":"10","author":"Lamatsch","year":"2015","journal-title":"PLoS One"},{"key":"2022011123503714800_bib48","unstructured":"Li, H\n          , 2013\u2003Aligning sequence reads, clone sequences and assembly contigs with BWA-MEM. \u00a0arXiv:1303.3997v2."},{"key":"2022011123503714800_bib49","doi-asserted-by":"publisher","first-page":"2078","DOI":"10.1093\/bioinformatics\/btp352","article-title":"The sequence alignment\/map format and SAMtools.","volume":"25","author":"Li","year":"2009","journal-title":"Bioinformatics"},{"key":"2022011123503714800_bib50","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1005678","article-title":"A tandem duplicate of anti-M\u00fcllerian hormone with a missense SNP on the Y chromosome is essential for male sex determination in nile Tilapia, Oreochromis niloticus.","volume":"11","author":"Li","year":"2015","journal-title":"PLoS Genet."},{"key":"2022011123503714800_bib51","doi-asserted-by":"publisher","first-page":"35768","DOI":"10.1074\/jbc.M103585200","article-title":"PDZ domain protein GIPC interacts with the cytoplasmic tail of melanosomal membrane protein gp75 (tyrosinase-related protein-1).","volume":"276","author":"Liu","year":"2001","journal-title":"J. Biol. Chem."},{"key":"2022011123503714800_bib52","doi-asserted-by":"publisher","first-page":"221","DOI":"10.2307\/2413708","article-title":"Molecules, morphology, and area cladograms - a cladistic and biogeographic analysis of Gambusia (teleostei, Poeciliidae).","volume":"44","author":"Lydeard","year":"1995","journal-title":"Syst. Biol."},{"key":"2022011123503714800_bib53","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1111\/j.1095-8312.2006.00558.x","article-title":"Evolution of alternative sex-determining mechanisms in teleost fishes.","volume":"87","author":"Mank","year":"2006","journal-title":"Biol. J. Linn. Soc. Lond."},{"key":"2022011123503714800_bib54","first-page":"393","article-title":"Density dependent aggressive advantage in melanistic male mosquitofish Gambusia affinis holbrooki (Girard).","volume":"40","author":"Martin","year":"1977","journal-title":"Fla. Sci."},{"key":"2022011123503714800_bib55","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1038\/nature751","article-title":"DMY is a Y-specific DM-domain gene required for male development in the medaka fish.","volume":"417","author":"Matsuda","year":"2002","journal-title":"Nature"},{"key":"2022011123503714800_bib56","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1111\/j.1365-294X.2006.02810.x","article-title":"Hybrid origin of a swordtail species (Teleostei: Xiphophorus clemenciae) driven by sexual selection.","volume":"15","author":"Meyer","year":"2006","journal-title":"Mol. Ecol."},{"key":"2022011123503714800_bib57","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1534\/genetics.111.137497","article-title":"Tracing the emergence of a novel sex-determining gene in medaka, Oryzias luzonensis.","volume":"191","author":"Myosho","year":"2012","journal-title":"Genetics"},{"key":"2022011123503714800_bib58","doi-asserted-by":"publisher","first-page":"12735","DOI":"10.1073\/pnas.0605317103","article-title":"Binding of internalized receptors to the PDZ domain of GIPC\/synectin recruits myosin VI to endocytic vesicles.","volume":"103","author":"Naccache","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2022011123503714800_bib59","doi-asserted-by":"publisher","first-page":"11778","DOI":"10.1073\/pnas.182314699","article-title":"A duplicated copy of DMRT1 in the sex-determining region of the Y chromosome of the medaka, Oryzias latipes.","volume":"99","author":"Nanda","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2022011123503714800_bib60","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1093\/genetics\/163.1.245","article-title":"Common spontaneous sex-reversed XX males of the medaka Oryzias latipes.","volume":"163","author":"Nanda","year":"2003","journal-title":"Genetics"},{"key":"2022011123503714800_bib61","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1007\/s00412-014-0455-z","article-title":"Sex chromosome polymorphism in guppies.","volume":"123","author":"Nanda","year":"2014","journal-title":"Chromosoma"},{"key":"2022011123503714800_bib62","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1038\/s41467-018-08014-y","article-title":"The evolution of sex determination associated with a chromosomal inversion.","volume":"10","author":"Natri","year":"2019","journal-title":"Nat. Commun."},{"key":"2022011123503714800_bib63","doi-asserted-by":"publisher","DOI":"10.1002\/9781119174844","volume-title":"Fishes of the World","author":"Nelson","year":"2016"},{"key":"2022011123503714800_bib64","doi-asserted-by":"publisher","first-page":"13984","DOI":"10.1073\/pnas.0705117104","article-title":"SOX9 is a key player in ultraviolet B-induced melanocyte differentiation and pigmentation.","volume":"104","author":"Passeron","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2022011123503714800_bib65","doi-asserted-by":"publisher","first-page":"1416","DOI":"10.1016\/j.cub.2004.08.030","article-title":"The master sex-determination locus in threespine sticklebacks is on a nascent Y chromosome.","volume":"14","author":"Peichel","year":"2004","journal-title":"Curr. Biol."},{"key":"2022011123503714800_bib66","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1146\/annurev.ecolsys.39.110707.173451","article-title":"Plague minnow or mosquito fish? A review of the biology and impacts of introduced Gambusia species.","volume":"39","author":"Pyke","year":"2008","journal-title":"Annu. Rev. Ecol. Evol. Syst."},{"key":"2022011123503714800_bib67","doi-asserted-by":"publisher","first-page":"139","DOI":"10.2307\/2423009","article-title":"Melanodimorphism in the poeciliid fish, Gambusia affinis (Baird and Girard).","volume":"65","author":"Regan","year":"1961","journal-title":"Am. Midl. Nat."},{"key":"2022011123503714800_bib68","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1007\/s10592-007-9367-2","article-title":"Population structure and genetic diversity of black redhorse (Moxostoma duquesnei) in a highly fragmented watershed.","volume":"9","author":"Reid","year":"2008","journal-title":"Conserv. Genet."},{"key":"2022011123503714800_bib69","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1126\/science.1174705","article-title":"Sexual conflict resolved by invasion of a novel sex determiner in Lake Malawi cichlid fishes.","volume":"326","author":"Roberts","year":"2009","journal-title":"Science"},{"key":"2022011123503714800_bib70","doi-asserted-by":"publisher","first-page":"1837","DOI":"10.1016\/j.cub.2003.10.027","article-title":"Switching between microtubule- and actin-based transport systems in melanophores is controlled by cAMP levels.","volume":"13","author":"Rodionov","year":"2003","journal-title":"Curr. Biol."},{"key":"2022011123503714800_bib71","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000391","article-title":"Turnover of sex chromosomes in the stickleback fishes (Gasterosteidae).","volume":"5","author":"Ross","year":"2009","journal-title":"PLoS Genet."},{"key":"2022011123503714800_bib72","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/j.ydbio.2011.08.008","article-title":"The cytoplasmic domain of TGFbetaR3 through its interaction with the scaffolding protein, GIPC, directs epicardial cell behavior.","volume":"358","author":"Sanchez","year":"2011","journal-title":"Dev. Biol."},{"key":"2022011123503714800_bib73"},{"key":"2022011123503714800_bib74","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1038\/ng.2604","article-title":"The genome of the platyfish, Xiphophorus maculatus, provides insights into evolutionary adaptation and several complex traits.","volume":"45","author":"Schartl","year":"2013","journal-title":"Nat. Genet."},{"key":"2022011123503714800_bib75","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1111\/pcmr.12409","article-title":"What is a vertebrate pigment cell?","volume":"29","author":"Schartl","year":"2016","journal-title":"Pigment Cell Melanoma Res."},{"key":"2022011123503714800_bib76","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1007\/s00412-015-0569-y","article-title":"Dynamics of vertebrate sex chromosome evolution: from equal size to giants and dwarfs.","volume":"125","author":"Schartl","year":"2016","journal-title":"Chromosoma"},{"key":"2022011123503714800_bib77","first-page":"1","article-title":"Racial investigations. IV. The genetic behavior of a secondary sexual character.","volume":"14","author":"Schmidt","year":"1920","journal-title":"C. R. Trav. Lab. Carlsberg"},{"key":"2022011123503714800_bib78","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1159\/000301339","article-title":"The chromosomes of Terraranan frogs. Insights into vertebrate cytogenetics.","volume":"568","author":"Schmid","year":"2010","journal-title":"Cytogenet. Genome Res."},{"key":"2022011123503714800_bib79","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1111\/j.1365-294X.1993.tb00103.x","article-title":"Cytonuclear genetic architecture in mosquitofish populations and the possible roles of introgressive hybridization.","volume":"2","author":"Scribner","year":"1993","journal-title":"Mol. Ecol."},{"key":"2022011123503714800_bib80","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1038\/nature06944","article-title":"Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer.","volume":"453","author":"Sekido","year":"2008","journal-title":"Nature"},{"key":"2022011123503714800_bib81","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004877","article-title":"Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma.","volume":"11","author":"Shakhova","year":"2015","journal-title":"PLoS Genet."},{"key":"2022011123503714800_bib82","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1186\/1471-2164-12-474","article-title":"High degree of sex chromosome differentiation in stickleback fishes.","volume":"12","author":"Shikano","year":"2011","journal-title":"BMC Genomics"},{"key":"2022011123503714800_bib83","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1038\/msb.2011.75","article-title":"Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega.","volume":"7","author":"Sievers","year":"2011","journal-title":"Mol. Syst. Biol."},{"key":"2022011123503714800_bib84","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1038\/nature08298","article-title":"The avian Z-linked gene DMRT1 is required for male sex determination in the chicken.","volume":"461","author":"Smith","year":"2009","journal-title":"Nature"},{"key":"2022011123503714800_bib85","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/0014-4827(72)90558-7","article-title":"A simple technique for demonstrating centromeric heterochromatin.","volume":"75","author":"Sumner","year":"1972","journal-title":"Exp. Cell Res."},{"key":"2022011123503714800_bib86","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1172\/JCI42580","article-title":"Identification of SOX3 as an XX male sex reversal gene in mice and humans.","volume":"121","author":"Sutton","year":"2011","journal-title":"J. Clin. Invest."},{"key":"2022011123503714800_bib87","doi-asserted-by":"publisher","first-page":"S157","DOI":"10.1111\/j.1440-169X.2008.00992.x","article-title":"Draft genome of the medaka fish: a comprehensive resource for medaka developmental genetics and vertebrate evolutionary biology.","volume":"50","author":"Takeda","year":"2008","journal-title":"Dev. Growth Differ."},{"key":"2022011123503714800_bib88","doi-asserted-by":"publisher","first-page":"4157","DOI":"10.1038\/ncomms5157","article-title":"Co-option of Sox3 as the male-determining factor on the Y chromosome in the fish Oryzias dancena.","volume":"5","author":"Takehana","year":"2014","journal-title":"Nat. Commun."},{"key":"2022011123503714800_bib89","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1093\/oxfordjournals.molbev.a040023","article-title":"Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees.","volume":"10","author":"Tamura","year":"1993","journal-title":"Mol. Biol. Evol."},{"key":"2022011123503714800_bib90","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1000025","article-title":"Neuropilin-1\/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells.","volume":"7","author":"Valdembri","year":"2009","journal-title":"PLoS Biol."},{"key":"2022011123503714800_bib91","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1038\/nature06178","article-title":"Turnover of sex chromosomes induced by sexual conflict.","volume":"449","author":"van Doorn","year":"2007","journal-title":"Nature"},{"key":"2022011123503714800_bib92","doi-asserted-by":"publisher","first-page":"8942","DOI":"10.1128\/MCB.00305-06","article-title":"GIPC is recruited by APPL to peripheral TrkA endosomes and regulates TrkA trafficking and signaling.","volume":"26","author":"Varsano","year":"2006","journal-title":"Mol. Cell. Biol."},{"key":"2022011123503714800_bib93","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1159\/000071590","article-title":"Sex determination and sex chromosome evolution in the medaka, Oryzias latipes, and the platyfish, Xiphophorus maculatus.","volume":"99","author":"Volff","year":"2002","journal-title":"Cytogenet. Genome Res."},{"key":"2022011123503714800_bib94","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1016\/0092-8674(94)90041-8","article-title":"Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9.","volume":"79","author":"Wagner","year":"1994","journal-title":"Cell"},{"key":"2022011123503714800_bib95","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1534\/genetics.103.019349","article-title":"A microsatellite genetic linkage map for Xiphophorus.","volume":"168","author":"Walter","year":"2004","journal-title":"Genetics"},{"key":"2022011123503714800_bib96","doi-asserted-by":"publisher","first-page":"1981","DOI":"10.1093\/molbev\/msv078","article-title":"Purifying selection maintains dosage-sensitive genes during degeneration of the threespine stickleback Y chromosome.","volume":"32","author":"White","year":"2015","journal-title":"Mol. Biol. Evol."},{"key":"2022011123503714800_bib97","doi-asserted-by":"publisher","first-page":"8375","DOI":"10.1002\/ece3.2562","article-title":"A genetically distinct hybrid zone occurs for two globally invasive mosquito fish species with striking phenotypic resemblance.","volume":"6","author":"Wilk","year":"2016","journal-title":"Ecol. Evol."},{"key":"2022011123503714800_bib98","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.1534\/genetics.114.169284","article-title":"Wild sex in zebrafish: loss of the natural sex determinant in domesticated strains.","volume":"198","author":"Wilson","year":"2014","journal-title":"Genetics"},{"key":"2022011123503714800_bib99","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1007\/BF02983078","article-title":"One-sided masculine and sex-linked inheritance in Lebistes reticulatus.","volume":"12","author":"Winge","year":"1922","journal-title":"J. Genet."},{"key":"2022011123503714800_bib100","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/BF03052599","article-title":"The location of eighteen genes in Lebistes reticulatus.","volume":"18","author":"Winge","year":"1927","journal-title":"J. Genet."},{"key":"2022011123503714800_bib101","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/0305-1978(90)90054-J","article-title":"Allozyme variation in a natural contact zone between Gambusia affinis and Gambusia holbrooki.","volume":"18","author":"Wooten","year":"1990","journal-title":"Biochem. Syst. Ecol."},{"key":"2022011123503714800_bib102","doi-asserted-by":"publisher","first-page":"283","DOI":"10.2307\/1445867","article-title":"Genetic-variability and systematics of Gambusia in the southeastern united-states.","volume":"1988","author":"Wooten","year":"1988","journal-title":"Copeia"},{"key":"2022011123503714800_bib103","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1242\/dev.01674","article-title":"A pair of Sox: distinct and overlapping functions of zebrafish sox9 co-orthologs in craniofacial and pectoral fin development.","volume":"132","author":"Yan","year":"2005","journal-title":"Development"},{"key":"2022011123503714800_bib104","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1016\/j.cub.2012.05.045","article-title":"An immune-related gene evolved into the master sex-determining gene in rainbow trout, Oncorhynchus mykiss.","volume":"22","author":"Yano","year":"2012","journal-title":"Curr. Biol."},{"key":"2022011123503714800_bib105","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1111\/eva.12032","article-title":"The sexually dimorphic on the Y-chromosome gene (sdY) is a conserved male-specific Y-chromosome sequence in many salmonids.","volume":"6","author":"Yano","year":"2013","journal-title":"Evol. Appl."}],"container-title":["Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/genetics\/article-pdf\/214\/1\/193\/42104907\/genetics0193.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/genetics\/article-pdf\/214\/1\/193\/42104907\/genetics0193.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T23:51:48Z","timestamp":1641945108000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/genetics\/article\/214\/1\/193\/5930515"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,1]]},"references-count":105,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,1,1]]},"published-print":{"date-parts":[[2020,1,1]]}},"URL":"https:\/\/doi.org\/10.1534\/genetics.119.302698","relation":{},"ISSN":["1943-2631"],"issn-type":[{"value":"1943-2631","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,1,1]]},"published":{"date-parts":[[2020,1,1]]}}}