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Surgical treatment for secundum atrial septal defects in patients &gt; 40 years old. A randomized clinical trial. J Am Coll Cardiol 2001; 38: 2035-42.","DOI":"10.1016\/S0735-1097(01)01635-7"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Beghetti M, Gali\u00e8 N, Bonnet D. Can \u201cinoperable\u201d congenital heart defects become operable in patients with pulmonary arterial hypertension? Dream or reality? Congenit Heart Dis 2012; 7: 3-11. (Review)","DOI":"10.1111\/j.1747-0803.2011.00611.x"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Warnes CA, Williams RG, Bashore TM, <i>et al<\/i>. ACC\/AHA 2008 Guidelines for the Management of Adults with Congenital Heart Disease: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines (writing committee to develop guidelines on the management of adults with congenital heart disease). 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Atrial septal defects versus ventricular septal defects in BREATHE-5, a placebo-controlled study of pulmonary arterial hypertension related to Eisenmenger\u2019s syndrome: a subgroup analysis. Int J Cardiol 2010; 144: 373-8.","DOI":"10.1016\/j.ijcard.2009.04.037"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Gatzoulis MA, Beghetti M, Gali\u00e8 N, <i>et al<\/i>. Longer-term bosentan therapy improves functional capacity in eisenmenger syndrome: results of the BREATHE-5 open-label extension study. Int J Cardiol 2008; 127: 27-32.","DOI":"10.1016\/j.ijcard.2007.04.078"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Jung IH, Lee SY, Lee SJ, <i>et al<\/i>. Device closure of a large atrial septal defect in a patient with severe pulmonary arterial hypertension after 1 year use of an oral endothelin receptor antagonist. J Cardiovasc Ultrasound 2013; 21: 140-4.","DOI":"10.4250\/jcu.2013.21.3.140"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Tahara N, Mizoguchi M, Honda A, <i>et al<\/i>. Successful shunt closure and improvement of hemodynamics in an ASD patient with severe pulmonary arterial hypertension and small shunt following a long-term use of bosentan. Int J Cardiol 2012; 158: e38-40.","DOI":"10.1016\/j.ijcard.2011.10.027"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Taniguchi Y, Emoto N, Miyagawa K, <i>et al<\/i>. Subsequent shunt closure after targeted medical therapy can be an effective strategy for secundum atrial septal defect with severe pulmonary arterial hypertension: two case reports : strategy for ASD with severe PAH. Heart Vessels 2014; 29: 282-5.","DOI":"10.1007\/s00380-013-0351-0"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Gali\u00e8 N, Hoeper MM, Humbert M, <i>et al<\/i>. Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J 2009; 30: 2493-537.","DOI":"10.1093\/eurheartj\/ehp297"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Inaba T, Yao A, Nakao T, <i>et al<\/i>. Volumetric and functional assessment of ventricles in pulmonary hypertension on 3-dimensional echocardiography. Circ J 2013; 77: 198-206.","DOI":"10.1253\/circj.CJ-12-0203"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Hatano M, Yao A, Shiga T, Kinugawa K, Hirata Y, Nagai R. Imatinib mesylate has the potential to exert its efficacy by down-regulating the plasma concentration of platelet-derived growth factor in patients with pulmonary arterial hypertension. Int Heart J 2010; 51: 272-6.","DOI":"10.1536\/ihj.51.272"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. LaFarge CG, Miettinen OS. The estimation of oxygen consumption. Cardiovasc Res 1970; 4: 23-30.","DOI":"10.1093\/cvr\/4.1.23"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Flamm MD, Cohn KE, Hancock EW. Measurement of systemic cardiac output at rest and exercise in patients with atrial septal defect. Am J Cardiol 1969; 23: 258-65.","DOI":"10.1016\/0002-9149(69)90075-7"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Sato T, Yamauchi H, Suzuki S, <i>et al<\/i>. Distinct prognostic factors in patients with chronic heart failure and chronic kidney disease. Int Heart J 2013; 54: 311-7.","DOI":"10.1536\/ihj.54.311"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Itoh H, Ajisaka R, Koike A, <i>et al<\/i>. Heart rate and blood pressure response to ramp exercise and exercise capacity in relation to age, gender, and mode of exercise in a healthy population. J Cardiol 2013; 61: 71-8.","DOI":"10.1016\/j.jjcc.2012.09.010"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Yamaki S, Kumate M, Yonesaka S, Maeda K, Endo M, Tabayashi K. Lung biopsy diagnosis of operative indication in secundum atrial septal defect with severe pulmonary vascular disease. Chest 2004; 126: 1042-7.","DOI":"10.1378\/chest.126.4.1042"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Bradley EA, Chakinala M, Billadello JJ. Usefulness of medical therapy for pulmonary hypertension and delayed atrial septal defect closure. Am J Cardiol 2013; 112: 1471-6.","DOI":"10.1016\/j.amjcard.2013.07.027"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Balint OH, Samman A, Haberer K, <i>et al<\/i>. 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