{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T22:09:45Z","timestamp":1768687785784,"version":"3.49.0"},"reference-count":25,"publisher":"International Heart Journal (Japanese Heart Journal)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int. Heart J."],"published-print":{"date-parts":[[2019,7,30]]},"DOI":"10.1536\/ihj.18-613","type":"journal-article","created":{"date-parts":[[2019,7,11]],"date-time":"2019-07-11T22:06:03Z","timestamp":1562882763000},"page":"796-804","source":"Crossref","is-referenced-by-count":5,"title":["Moderate Chronic Ischemic Mitral Regurgitation"],"prefix":"10.1536","volume":"60","author":[{"given":"JinQiang","family":"Shen","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Zhongshan Hospital Fudan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LiMin","family":"Xia","sequence":"additional","affiliation":[{"name":"Shanghai Institute of Cardiovascular Disease"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"Song","sequence":"additional","affiliation":[{"name":"Shanghai Institute of Cardiovascular Disease"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YuLin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Zhongshan Hospital Fudan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ye","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Zhongshan Hospital Fudan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"WenJun","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Zhongshan Hospital Fudan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Zhongshan Hospital Fudan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ChunSheng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Zhongshan Hospital Fudan University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"437","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Sandoval Y, Sorajja P, Harris KM. Contemporary management of ischemic mitral regurgitation: a review. Am J Med 2018; 131: 887-95.","DOI":"10.1016\/j.amjmed.2018.01.048"},{"key":"2","unstructured":"2. Malhotra AK, Evans AS, Weiner MM, Ramakrishna H. Ischemic mitral regurgitation: a paradigm shift in surgical management? J Cardiothorac Vasc Anesth 2018; 32: 580-5."},{"key":"3","unstructured":"3. Salmasi MY, Harky A, Chowdhury MF, <i>et al<\/i>. Should the mitral valve be repaired for moderate ischemic mitral regurgitation at the time of revascularization surgery? J Card Surg 2018; 33: 374-84."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Virk SA, Tian DH, Sriravindrarajah A, <i>et al<\/i>. Mitral valve surgery and coronary artery bypass grafting for moderate-to-severe ischemic mitral regurgitation: Meta-analysis of clinical and echocardiographic outcomes. J Thorac Cardiovasc Surg 2017; 154: 127-36.","DOI":"10.1016\/j.jtcvs.2017.03.039"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Milano CA, Daneshmand MA, Rankin JS, <i>et al<\/i>. Survival prognosis and surgical management of ischemic mitral regurgitation. Ann Thorac Surg 2008; 86: 735-44.","DOI":"10.1016\/j.athoracsur.2008.05.017"},{"key":"6","first-page":"I499","volume":"114","year":"2006","unstructured":"6. Kang DH, Kim MJ, Kang SJ, <i>et al<\/i>. Mitral valve repair versus revascularization alone in the treatment of ischemic mitral regurgitation. Circulation 2006; 114: I499-503.","journal-title":"Circulation","ISSN":"https:\/\/id.crossref.org\/issn\/0009-7322","issn-type":"print"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Wong DR, Agnihotri AK, Hung JW, <i>et al<\/i>. Long-term survival after surgical revascularization for moderate ischemic mitral regurgitation. Ann Thorac Surg 2005; 80: 570-7.","DOI":"10.1016\/j.athoracsur.2005.03.034"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Diodato MD, Moon MR, Pasque MK, <i>et al<\/i>. Repair of ischemic mitral regurgitation does not increase mortality or improve long-term survival in patients undergoing coronary artery revascularization: a propensity analysis. Ann Thorac Surg 2004; 78: 794-9.","DOI":"10.1016\/j.athoracsur.2004.03.022"},{"key":"9","unstructured":"9. Malhotra A, Ananthanarayanan C, Wadhawa V, <i>et al<\/i>. OPCABG for moderate CIMR in elderly patients: a superior option? Braz J Cardiovasc Surg 2018; 33: 15-22."},{"key":"10","doi-asserted-by":"publisher","unstructured":"10. Chan KM, Punjabi PP, Flather M, <i>et al<\/i>. Coronary artery bypass surgery with or without mitral valve annuloplasty in moderate functional ischemic mitral regurgitation: final results of the Randomized Ischemic Mitral Evaluation (RIME) trial. Circulation 2012; 126: 2502-10.","DOI":"10.1161\/CIRCULATIONAHA.112.143818"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Timek TA, Hooker RL, Collingwood R, <i>et al<\/i>. Five-year real world outcomes of GeoForm ring implantation in patients with ischemic mitral regurgitation. J Thorac Cardiovasc Surg 2014; 148: 1951-6.","DOI":"10.1016\/j.jtcvs.2014.02.051"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Sun X, Huang J, Shi M, Huang G, Pang L, Wang Y. Predictors of moderate ischemic mitral regurgitation improvement after off-pump coronary artery bypass. J Thorac Cardiovasc Surg 2015; 149: 1606-12.","DOI":"10.1016\/j.jtcvs.2015.02.047"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Bouchard D, Jensen H, Carrier M, <i>et al<\/i>. Effect of systematic downsizing rigid ring annuloplasty in patients with moderate ischemic mitral regurgitation. J Thorac Cardiovasc Surg 2014; 147: 1471-7.","DOI":"10.1016\/j.jtcvs.2013.05.024"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Rabbah JP, Siefert AW, Bolling SF, Yoganathan AP. Mitral valve annuloplasty and anterior leaflet augmentation for functional ischemic mitral regurgitation: quantitative comparison of coaptation and subvalvular tethering. J Thorac Cardiovasc Surg 2014; 148: 1688-93.","DOI":"10.1016\/j.jtcvs.2014.04.008"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Smith PK, Puskas JD, Ascheim DD, <i>et al<\/i>. Surgical treatment of moderate ischemic mitral regurgitation. N Engl J Med 2014; 371: 2178-88.","DOI":"10.1056\/NEJMoa1410490"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Kron IL, LaPar DJ, Acker MA, <i>et al<\/i>. 2016 update to The American Association for Thoracic Surgery consensus guidelines: Ischemic mitral valve regurgitation. J Thorac Cardiovasc Surg 2017; 153: 1076-9.","DOI":"10.1016\/j.jtcvs.2016.11.068"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Nishimura RA, Otto CM, Bonow RO, <i>et al<\/i>. 2014 AHA\/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2014; 63: e57-e185.","DOI":"10.1161\/CIR.0000000000000031"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Carmona P, Paredes F, Mateo E, Mena-Dur\u00e1n AV, Hornero F, Mart\u00ednez-Le\u00f3n J. Is off-pump technique a safer procedure for coronary revascularization? A propensity score analysis of 20 years of experience. Interact Cardiovasc Thorac Surg 2016; 22: 612-8.","DOI":"10.1093\/icvts\/ivw005"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Ji Q, Lai H, Sun Y, <i>et al<\/i>. Impact of presurgical mild acute respiratory distress syndrome on surgical mortality after surgical repair of acute type A aortic dissection. Int Heart J 2017; 58: 739-45.","DOI":"10.1536\/ihj.16-306"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Xia L, Ji Q, Song K, <i>et al<\/i>. Early clinical outcomes of on-pump beating-heart versus off-pump technique for surgical revascularization in patients with severe left ventricular dysfunction: the experience of a single center. J Cardiothorac Surg 2017; 12: 11.","DOI":"10.1186\/s13019-017-0572-x"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Fattouch K, Guccione F, Sam pognaro R, <i>et al<\/i>. POINT: Efficacy of adding mitral valve restrictive annuloplasty to coronary artery bypass grafting in patients with moderate ischemic mitral valve regurgitation: a randomized trial. J Thorac Cardiovasc Surg 2009; 138: 278-85.","DOI":"10.1016\/j.jtcvs.2008.11.010"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Michler RE, Smith PK, Parides MK, <i>et al<\/i>. Two-year outcomes of surgical treatment of moderate ischemic mitral regurgitation. N Engl J Med 2016; 374: 1932-41.","DOI":"10.1056\/NEJMoa1602003"},{"key":"23","unstructured":"23. Jensen H. Surgical treatment of functional ischemic mitral regurgitation. Dan Med J 2015; 62: B4993."},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Sablotzki A, Welters I, Lehmann N, <i>et al<\/i>. Plasma levels of immunoinhibitory cytokines interleukin-10 and transforming growth factor-beta in patients undergoing coronary artery bypass grafting. Eur J Cardiothorac Surg 1997; 11: 763-8.","DOI":"10.1016\/S1010-7940(97)01154-8"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Taylor KM. Brain damage during cardiopulmonary bypass. Ann Thorac Surg 1998; 65: S20-6.","DOI":"10.1016\/S0003-4975(98)00072-1"}],"container-title":["International Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/ihj\/60\/4\/60_18-613\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,27]],"date-time":"2019-07-27T03:43:35Z","timestamp":1564199015000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/ihj\/60\/4\/60_18-613\/_article"}},"subtitle":["Concomitant Mitral Valve Surgery or Coronary Artery Bypass Grafting Alone? Insights from a Single-Center Study of Propensity-Matched Data"],"short-title":[],"issued":{"date-parts":[[2019,7,30]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.1536\/ihj.18-613","relation":{},"ISSN":["1349-2365","1349-3299"],"issn-type":[{"value":"1349-2365","type":"print"},{"value":"1349-3299","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,30]]}}}