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Koelling TM, Aaronson KD, Cody RJ, Bach DS, Armstrong WF. Prognostic significance of mitral regurgitation and tricuspid regurgitation in patients with left ventricular systolic dysfunction. Am Heart J 2002; 144: 524-9.","DOI":"10.1067\/mhj.2002.123575"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Trichon BH, Felker GM, Shaw LK, Cabell CH, O&apos;Connor CM. Relation of frequency and severity of mitral regurgitation to survival among patients with left ventricular systolic dysfunction and heart failure. Am J Cardiol 2003; 91: 538-43.","DOI":"10.1016\/S0002-9149(02)03301-5"},{"key":"3","unstructured":"3. Dickstein K, Vardas PE, Auricchio A, <i>et al<\/i>. 2010 Focused Update of ESC Guidelines on device therapy in heart failure: an update of the 2008 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure and the 2007 ESC guidelines for cardiac and resynchronization therapy. 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Kaneko H, Suzuki S, Uejima T, <i>et al<\/i>. Prevalence and the long-term prognosis of functional mitral regurgitation in Japanese patients with symptomatic heart failure. Heart Vessels 2014; 29: 801-7.","DOI":"10.1007\/s00380-013-0448-5"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Kaneko H, Suzuki S, Uejima T, <i>et al<\/i>. Functional mitral regurgitation and left ventricular systolic dysfunction in the recent era of cardiovascular clinical practice, an observational cohort study. Hypertens Res 2014; 37: 1082-7.","DOI":"10.1038\/hr.2014.122"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Capomolla S, Febo O, Gnemmi M, <i>et al<\/i>. Beta-blockade therapy in chronic heart failure: diastolic function and mitral regurgitation improvement by carvedilol. Am Heart J 2000; 139: 596-608.","DOI":"10.1016\/S0002-8703(00)90036-X"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Comin-Colet J, Sanchez-Corral MA, Manito N, <i>et al<\/i>. Effect of carvedilol therapy on functional mitral regurgitation, ventricular remodeling, and contractility in patients with heart failure due to left ventricular systolic dysfunction. Transplant Proc 2002; 34: 177-8.","DOI":"10.1016\/S0041-1345(01)02717-8"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Lowes BD, Gill EA, Abraham WT, <i>et al<\/i>. Effects of carvedilol on left ventricular mass, chamber geometry, and mitral regurgitation in chronic heart failure. Am J Cardiol 1999; 83: 1201-5.","DOI":"10.1016\/S0002-9149(99)00059-4"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Levine AB, Muller C, Levine TB. Effects of high-dose lisinopril-isosorbide dinitrate on severe mitral regurgitation and heart failure remodeling. Am J Cardiol 1998; 82: 1299-301.","DOI":"10.1016\/S0002-9149(98)00623-7"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Agricola E, Ielasi A, Oppizzi M, <i>et al<\/i>. Long-term prognosis of medically treated patients with functional mitral regurgitation and left ventricular dysfunction. Eur J Heart Fail 2009; 11: 581-7.","DOI":"10.1093\/eurjhf\/hfp051"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Breithardt OA, Sinha AM, Schwammenthal E, <i>et al<\/i>. Acute effects of cardiac resynchronization therapy on functional mitral regurgitation in advanced systolic heart failure. J Am Coll Cardiol 2003; 41: 765-70.","DOI":"10.1016\/S0735-1097(02)02937-6"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. van Bommel RJ, Marsan NA, Delgado V, <i>et al<\/i>. Cardiac resynchronization therapy as a therapeutic option in patients with moderate-severe functional mitral regurgitation and high operative risk. Circulation 2011; 124: 912-9.","DOI":"10.1161\/CIRCULATIONAHA.110.009803"},{"key":"15","doi-asserted-by":"publisher","unstructured":"15. St John Sutton MG, Plappert T, Abraham WT, <i>et al<\/i>. Effect of cardiac resynchronization therapy on left ventricular size and function in chronic heart failure. Circulation 2003; 107: 1985-90.","DOI":"10.1161\/01.CIR.0000065226.24159.E9"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Onishi T, Onishi T, Marek JJ, <i>et al<\/i>. Mechanistic features associated with improvement in mitral regurgitation after cardiac resynchronization therapy and their relation to long-term patient outcome. Circ Heart Fail 2013; 6: 685-93.","DOI":"10.1161\/CIRCHEARTFAILURE.112.000112"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Nishimura RA, Otto CM, Bonow RO, <i>et al<\/i>. 2017 AHA\/ACC Focused Update of the 2014 AHA\/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines. 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Goldstein D, Moskowitz AJ, Gelijns AC, <i>et al<\/i>. Two-Year Outcomes of Surgical Treatment of Severe Ischemic Mitral Regurgitation. N Engl J Med 2016; 374: 344-53.","DOI":"10.1056\/NEJMoa1512913"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Smith PK, Puskas JD, Ascheim DD, <i>et al<\/i>. Surgical treatment of moderate ischemic mitral regurgitation. N Engl J Med 2014; 371: 2178-88.","DOI":"10.1056\/NEJMoa1410490"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Mauri L, Foster E, Glower DD, <i>et al<\/i>. 4-year results of a randomized controlled trial of percutaneous repair versus surgery for mitral regurgitation. J Am Coll Cardiol 2013; 62: 317-28.","DOI":"10.1016\/j.jacc.2013.04.030"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Maisano F, Franzen O, Baldus S, <i>et al<\/i>. 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