{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T10:22:26Z","timestamp":1780050146107,"version":"3.53.1"},"reference-count":31,"publisher":"International Heart Journal (Japanese Heart Journal)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int. Heart J."],"published-print":{"date-parts":[[2024,9,30]]},"DOI":"10.1536\/ihj.24-192","type":"journal-article","created":{"date-parts":[[2024,9,29]],"date-time":"2024-09-29T22:14:23Z","timestamp":1727648063000},"page":"817-822","source":"Crossref","is-referenced-by-count":1,"title":["Association Between Disease Severity and Frailty in Patients with Aortic Stenosis"],"prefix":"10.1536","volume":"65","author":[{"given":"Yasutomo","family":"Tanaka","sequence":"first","affiliation":[{"name":"Department of Physical Therapy Science, Nagasaki University Graduate School of Biomedical Sciences"},{"name":"Department of Rehabilitation Medicine, Nagasaki University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yudai","family":"Yano","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy Science, Nagasaki University Graduate School of Biomedical Sciences"},{"name":"Department of Rehabilitation Medicine, Nagasaki University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsubasa","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy Science, Nagasaki University Graduate School of Biomedical Sciences"},{"name":"Department of Rehabilitation Medicine, Nagasaki University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsuyoshi","family":"Yonekura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsufumi","family":"Motokawa","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Takahata","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Nagasaki University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Maemura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Kozu","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy Science, Nagasaki University Graduate School of Biomedical Sciences"},{"name":"Department of Rehabilitation Medicine, Nagasaki University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"437","reference":[{"key":"1","doi-asserted-by":"publisher","unstructured":"1. Tanaka H, Kim YJ, Park SJ, Park SW, <i>et al<\/i>. Comparison between characteristics of severe and very severe aortic stenosis. Echocardiography 2018; 35: 430-7.","DOI":"10.1111\/echo.13816"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Eveborn GW, Schirmer H, Heggelund G, Lunde P, Rasmussen K. The evolving epidemiology of valvular aortic stenosis. the Tromso study. Heart 2013; 99: 396-400.","DOI":"10.1136\/heartjnl-2012-302265"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Ramos M, Quezada M, Ayala R, <i>et al<\/i>. Asymptomatic aortic stenosis in a geriatric population. The role of frailty and comorbidity in mortality. Rev Esp Cardiol (Engl Ed) 2021; 74: 167-74.","DOI":"10.1016\/j.rec.2019.11.006"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Kojima G, Iliffe S, Jivraj S, Walters K. Association between frailty and quality of life among community-dwelling older people: a systematic review and meta-analysis. J Epidemiol Community Health 2016; 70: 716-21.","DOI":"10.1136\/jech-2015-206717"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Fukui S, Kawakami M, Otaka Y, <i>et al<\/i>. Physical frailty in older people with severe aortic stenosis. Aging Clin Exp Res 2016; 28: 1081-7.","DOI":"10.1007\/s40520-015-0507-0"},{"key":"6","doi-asserted-by":"publisher","unstructured":"6. Lester SJ, Heilbron B, Gin K, Dodek A, Jue J. The natural history and rate of progression of aortic stenosis. Chest 1998; 113: 1109-14.","DOI":"10.1378\/chest.113.4.1109"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Marengoni A, Zucchelli A, Vetrano DL, <i>et al<\/i>. Heart failure, frailty, and pre-frailty: A systematic review and meta-analysis of observational studies. Int J Cardiol 2020; 316: 161-71.","DOI":"10.1016\/j.ijcard.2020.04.043"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Ozawa T, Yamashita M, Seino S, <i>et al<\/i>. Standardized gait speed ratio in elderly patients with heart failure. ESC Heart Fail 2021; 8: 3557-65.","DOI":"10.1002\/ehf2.13392"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Lv S, Ru S. The prevalence of malnutrition and its effects on the all-cause mortality among patients with heart failure: A systematic review and meta-analysis. PLoS One 2021; 16: e0259300.","DOI":"10.1371\/journal.pone.0259300"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Rockwood K, Song X, MacKnight C, <i>et al<\/i>. A global clinical measure of fitness and frailty in elderly people. CMAJ 2005; 173: 489-95.","DOI":"10.1503\/cmaj.050051"},{"key":"11","doi-asserted-by":"publisher","unstructured":"11. Shimura T, Yamamoto M, Kano S, <i>et al<\/i>. Impact of the Clinical Frailty Scale on Outcomes After Transcatheter Aortic Valve Replacement. Circulation 2017; 135: 2013-24.","DOI":"10.1161\/CIRCULATIONAHA.116.025630"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Shimizu K, Sadatomo T, Hara T, Onishi S, Yuki K, Kurisu K. Importance of frailty evaluation in the prediction of the prognosis of patients with chronic subdural hematoma. Geriatr Gerontol Int 2018; 18: 1173-6.","DOI":"10.1111\/ggi.13436"},{"key":"13","doi-asserted-by":"publisher","unstructured":"13. Nishimura RA, Otto CM, Bonow RO, <i>et al<\/i>. 2014 AHA\/ACC Guideline for the Management of Patients With Valvular Heart Disease: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines. Circulation 2014; 129: e521-643.","DOI":"10.1161\/CIR.0000000000000031"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Ideno Y, Takayama M, Hayashi K, Takagi H, Sugai Y. Evaluation of a Japanese version of the Mini-Mental State Examination in elderly persons. Geriatr Gerontol Int 2012; 12: 310-6.","DOI":"10.1111\/j.1447-0594.2011.00772.x"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Afilalo J, Eisenberg MJ, Morin JF, <i>et al<\/i>. Gait speed as an incremental predictor of mortality and major morbidity in elderly patients undergoing cardiac surgery. J Am Coll Cardiol 2010; 56: 1668-76.","DOI":"10.1016\/j.jacc.2010.06.039"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Kano S, Yamamoto M, Shimura T, <i>et al<\/i>. Gait Speed Can Predict Advanced Clinical Outcomes in Patients Who Undergo Transcatheter Aortic Valve Replacement: Insights From a Japanese Multicenter Registry. Circ Cardiovasc Interv 2017; 10: e005088.","DOI":"10.1161\/CIRCINTERVENTIONS.117.005088"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Shibata K, Yamamoto M, Kano S, <i>et al<\/i>. Importance of Geriatric Nutritional Risk Index assessment in patients undergoing transcatheter aortic valve replacement. Am Heart J 2018; 202: 68-75.","DOI":"10.1016\/j.ahj.2018.04.021"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Bouillanne O, Morineau G, Dupont C, <i>et al<\/i>. Geriatric Nutritional Risk Index: a new index for evaluating at-risk elderly medical patients. Am J Clin Nutr 2005; 82: 777-83.","DOI":"10.1093\/ajcn\/82.4.777"},{"key":"19","doi-asserted-by":"publisher","unstructured":"19. Mack MJ, Leon MB, Smith CR, <i>et al<\/i>. 5-year outcomes of transcatheter aortic valve replacement or surgical aortic valve replacement for high surgical risk patients with aortic stenosis (PARTNER 1): a randomised controlled trial. Lancet 2015; 385: 2477-84.","DOI":"10.1016\/S0140-6736(15)60308-7"},{"key":"20","doi-asserted-by":"publisher","unstructured":"20. Al-Mohammad A, Mant J. The diagnosis and management of chronic heart failure: review following the publication of the NICE guidelines. Heart 2011; 97: 411-6.","DOI":"10.1136\/hrt.2010.214999"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Tsutsui H, Albert NM, Coats AJS, <i>et al<\/i>. Natriuretic Peptides: Role in the Diagnosis and Management of Heart Failure: A Scientific Statement From the Heart Failure Association of the European Society of Cardiology, Heart Failure Society of America and Japanese Heart Failure Society. J Card Fail 2023; 29: 787-804.","DOI":"10.1016\/j.cardfail.2023.02.009"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Huded CP, Huded JM, Friedman JL, <i>et al<\/i>. Frailty Status and Outcomes After Transcatheter Aortic Valve Implantation. Am J Cardiol 2016; 117: 1966-71.","DOI":"10.1016\/j.amjcard.2016.03.044"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Green P, Woglom AE, Genereux P, <i>et al<\/i>. Gait speed and dependence in activities of daily living in older adults with severe aortic stenosis. Clin Cardiol 2012; 35: 307-14.","DOI":"10.1002\/clc.21974"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Izumi C, Eishi K, Ashihara K, <i>et al<\/i>. JCS\/JSCS\/JATS\/JSVS 2020 Guidelines on the Management of Valvular Heart Disease. Circ J 2020; 84: 2037-119.","DOI":"10.1253\/circj.CJ-20-0135"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Fried LP, Tangen CM, Walston J, <i>et al<\/i>. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001; 56: M146-56.","DOI":"10.1093\/gerona\/56.3.M146"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Rogers T, Alraies MC, Moussa Pacha H, <i>et al<\/i>. Clinical Frailty as an Outcome Predictor After Transcatheter Aortic Valve Implantation. Am J Cardiol 2018; 121: 850-5.","DOI":"10.1016\/j.amjcard.2017.12.035"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Okoh AK, Haik N, Singh S, <i>et al<\/i>. Discharge disposition of older patients undergoing trans-catheter aortic valve replacement and its impact on survival. Catheter Cardiovasc Interv 2019; 94: 448-55.","DOI":"10.1002\/ccd.28069"},{"key":"28","doi-asserted-by":"publisher","unstructured":"28. Gouda P, Paterson C, Meyer S, <i>et al<\/i>. Effects of Transcatheter Aortic Valve Implantation on Frailty and Quality of Life. CJC Open 2020; 2: 79-84.","DOI":"10.1016\/j.cjco.2019.12.006"},{"key":"29","doi-asserted-by":"publisher","unstructured":"29. Fletcher GF, Ades PA, Kligfield P, <i>et al<\/i>. Exercise standards for testing and training: a scientific statement from the American Heart Association. Circulation 2013; 128: 873-934.","DOI":"10.1161\/CIR.0b013e31829b5b44"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Sasaki M, Sasaki KI, Ishizaki Y, <i>et al<\/i>. Safety and Efficacy of a Bodyweight Exercise Training Program in Symptomatic Patients With Severe Aortic Valve Stenosis. Am J Cardiol 2023; 186: 163-9.","DOI":"10.1016\/j.amjcard.2022.09.021"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Tarazona-Santabalbina FJ, Gomez-Cabrera MC, Perez-Ros P, <i>et al<\/i>. A Multicomponent Exercise Intervention that Reverses Frailty and Improves Cognition, Emotion, and Social Networking in the Community-Dwelling Frail Elderly: A Randomized Clinical Trial. J Am Med Dir Assoc 2016; 17: 426-33.","DOI":"10.1016\/j.jamda.2016.01.019"}],"container-title":["International Heart Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/ihj\/65\/5\/65_24-192\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,5]],"date-time":"2024-10-05T04:11:37Z","timestamp":1728101497000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/ihj\/65\/5\/65_24-192\/_article"}},"subtitle":["A Single-Center Retrospective Study"],"short-title":[],"issued":{"date-parts":[[2024,9,30]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.1536\/ihj.24-192","relation":{},"ISSN":["1349-2365","1349-3299"],"issn-type":[{"value":"1349-2365","type":"print"},{"value":"1349-3299","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,30]]},"article-number":"24-192"}}