{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T09:11:46Z","timestamp":1762161106626},"reference-count":23,"publisher":"Japanese Association for Laboratory Animal Science","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp. Anim."],"published-print":{"date-parts":[[2014]]},"DOI":"10.1538\/expanim.63.305","type":"journal-article","created":{"date-parts":[[2014,7,30]],"date-time":"2014-07-30T00:37:31Z","timestamp":1406680651000},"page":"305-310","source":"Crossref","is-referenced-by-count":4,"title":["Plasma Proteome Analysis on Cynomolgus Monkey (&lt;i&gt;Macaca            Fascicularis&lt;\/i&gt;) Pedigrees with Early Onset Drusen Formation"],"prefix":"10.1538","volume":"63","author":[{"given":"Hiroaki","family":"Kobayashi","sequence":"first","affiliation":[{"name":"Division of Molecular &Cellular Biology, National              Institute of Sensory Organs, National Hospital Organization Tokyo Medical Center,              2-5-1 Higashigaoka, Meguro-ku, Tokyo 152-8902, Japan"},{"name":"Department of Ophthalmology, Juntendo University,              2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haru","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Division of Molecular &Cellular Biology, National              Institute of Sensory Organs, National Hospital Organization Tokyo Medical Center,              2-5-1 Higashigaoka, Meguro-ku, Tokyo 152-8902, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Murakami","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Juntendo University,              2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Iwata","sequence":"additional","affiliation":[{"name":"Division of Molecular &Cellular Biology, National              Institute of Sensory Organs, National Hospital Organization Tokyo Medical Center,              2-5-1 Higashigaoka, Meguro-ku, Tokyo 152-8902, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"439","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Anderson D.H., Ozaki S., Nealon M., Neitz J., Mullins R.F., Hageman G.S., and Johnson L.V. 2001. Local cellular sources of apolipoprotein E in the human retina and retinal pigmented epithelium: implications for the process of drusen formation. <i>Am. J. Ophthalmol.<\/i> 131: 767\u2013781.","DOI":"10.1016\/S0002-9394(00)00961-2"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Anderson D.H., Radeke M.J., Gallo N.B., Chapin E.A., Johnson P.T., Curletti C.R., Hancox L.S., Hu J., Ebright J.N., Malek G., Hauser M.A., Rickman C.B., Bok D., Hageman G.S., and Johnson L.V. 2010. The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited. <i>Prog. Retin. Eye Res.<\/i> 29: 95\u2013112.","DOI":"10.1016\/j.preteyeres.2009.11.003"},{"key":"3","unstructured":"3. Anderson N.L., and Anderson N.G. 2002. The human plasma proteome: history, character, and diagnostic prospects. <i>Mol. Cell. Proteomics<\/i> 1: 845\u2013867."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Drabovich A.P., and Diamandis E.P. 2010. Combinatorial peptide libraries facilitate development of multiple reaction monitoring assays for low-abundance proteins. <i>J. Proteome Res.<\/i> 9: 1236\u20131245.","DOI":"10.1021\/pr900729g"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Crabb J.W., Miyagi M., Gu X., Shadrach K., West K.A., Sakaguchi H., Kamei M., Hasan A., Yan L., Rayborn M.E., Salomon R.G., and Hollyfield J.G. 2002. Drusen proteome analysis: an approach to the etiology of age-related macular degeneration. <i>Proc. Natl. Acad. Sci. USA<\/i> 99: 14682\u201314687.","DOI":"10.1073\/pnas.222551899"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Curcio C.A., Johnson M., Rudolf M., and Huang J.D. 2011. The oil spill in ageing Bruch membrane. <i>Br. J. Ophthalmol.<\/i> 95: 1638\u20131645.","DOI":"10.1136\/bjophthalmol-2011-300344"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Dashti N., McGwin G.., Owsley C., and Curcio C.A. 2006. Plasma apolipoproteins and risk for age related maculopathy. <i>Br. J. Ophthalmol.<\/i> 90: 1028\u20131033.","DOI":"10.1136\/bjo.2006.093856"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Guerrier L., Righetti P.G., and Boschetti E. 2008. Reduction of dynamic protein concentration range of biological extracts for the discovery of low-abundance proteins by means of hexapeptide ligand library. <i>Nat. Protoc.<\/i> 3: 883\u2013890.","DOI":"10.1038\/nprot.2008.59"},{"key":"9","unstructured":"9. Bu G. 2009. Apolipoprotein E and its receptors in Alzheimer\u2019s disease: pathways, pathogenesis and therapy. <i>Nat. Rev. Neurosci.<\/i> 10: 333\u2013344."},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Johnson L.V., Forest D.L., Banna C.D., Radeke C.M., Maloney M.A., Hu J., Spencer C.N., Walker A.M., Tsie M.S., Bok D., Radeke M.J., and Anderson D.H. 2011. Cell culture model that mimics drusen formation and triggers complement activation associated with age-related macular degeneration. <i>Proc. Natl. Acad. Sci. USA<\/i> 108: 18277\u201318282.","DOI":"10.1073\/pnas.1109703108"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Liu H., Sadygov R.G., and Yates J.R. 2004. A model for random sampling and estimation of relative protein abundance in shotgun proteomics. <i>Anal. Chem.<\/i> 76: 4193\u20134201.","DOI":"10.1021\/ac0498563"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Mahley R.W. 1988. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. <i>Science<\/i> 240: 622\u2013630.","DOI":"10.1126\/science.3283935"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Mullins R.F., Russell S.R., Anderson D.H., and Hageman G.S. 2000. Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease. <i>FASEB J.<\/i> 14: 835\u2013846.","DOI":"10.1096\/fasebj.14.7.835"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Okamoto H., Umeda S., Nozawa T., Suzuki M.T., Yoshikawa Y., Matsuura E.T., and Iwata T. 2010. Comparative proteomic analyses of macular and peripheral retina of cynomolgus monkeys (Macaca fascicularis). <i>Exp. Anim.<\/i> 59: 171\u2013182.","DOI":"10.1538\/expanim.59.171"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Poon I.K., Patel K.K., Davis D.S., Parish C.R., and Hulett M.D. 2011. Histidine-rich glycoprotein: the Swiss Army knife of mammalian plasma. <i>Blood<\/i> 117: 2093\u20132101.","DOI":"10.1182\/blood-2010-09-303842"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Tran J.C. and Doucette A.A. 2009. Multiplexed size separation of intact proteins in solution phase for mass spectrometry. <i>Anal. Chem.<\/i> 81: 6201\u20136209.","DOI":"10.1021\/ac900729r"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Umeda S., Ayyagari R., Allikmets R., Suzuki M.T., Karoukis A.J., Ambasudhan R., Zernant J., Okamoto H., Ono F., Terao K., Mizota A., Yoshikawa Y., Tanaka Y., and Iwata T. 2005. Early-onset macular degeneration with drusen in a cynomolgus monkey (<i>Macaca fascicularis<\/i>) pedigree: exclusion of 13 candidate genes and loci. <i>Invest. Ophthalmol. Vis. Sci.<\/i> 46: 683\u2013691.","DOI":"10.1167\/iovs.04-1031"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Umeda S., Ayyagari R., Suzuki M.T., Ono F., Iwata F., Fujiki K., Kanai A., Takada Y., Yoshikawa Y., Tanaka Y., and Iwata T. 2003. Molecular cloning of ELOVL4 gene from cynomolgus monkey (<i>Macaca fascicularis<\/i>). <i>Exp. Anim.<\/i> 52: 129\u2013135.","DOI":"10.1538\/expanim.52.129"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Umeda S., Suzuki M.T., Okamoto H., Ono F., Mizota A., Terao K., Yoshikawa Y., Tanaka Y., and Iwata T. 2005. Molecular composition of drusen and possible involvement of anti-retinal autoimmunity in two different forms of macular degeneration in cynomolgus monkey (<i>Macaca fascicularis<\/i>). <i>FASEB J.<\/i> 19: 1683\u20131685.","DOI":"10.1096\/fj.04-3525fje"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Vingerling J.R., Klaver C.C., Hofman A., and de Jong P.T. 1995. Epidemiology of age-related maculopathy. <i>Epidemiol. Rev.<\/i> 17: 347\u2013360.","DOI":"10.1093\/oxfordjournals.epirev.a036198"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Wang L., Li C.M., Rudolf M., Belyaeva O.V., Chung B.H., Messinger J.D., Kedishvili N.Y., and Curcio C.A. 2009. Lipoprotein particles of intraocular origin in human Bruch membrane: an unusual lipid profile. <i>Invest. Ophthalmol. Vis. Sci.<\/i> 50: 870\u2013877.","DOI":"10.1167\/iovs.08-2376"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Witkowski C. and Harkins J. 2009. Using the GELFREE 8100 Fractionation System for molecular weight-based fractionation with liquid phase recovery. <i>J. Vis. Exp.<\/i> 34: 1842.","DOI":"10.3791\/1842"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Xiaoyun F., Sina A.G., Pattie S.G., Moira L.A., David A.F., David R.P., Tomas V., and Jay W.H. 2007. Spectral Index for Assessment of Diffential Protein Expression in Shotgun Proteomics. <i>J. Proteome<\/i> 7: 845\u2013854.","DOI":"10.1021\/pr070271+"}],"container-title":["Experimental Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/expanim\/63\/3\/63_13-0101\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,19]],"date-time":"2021-04-19T09:50:15Z","timestamp":1618825815000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/expanim\/63\/3\/63_13-0101\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1538\/expanim.63.305","relation":{},"ISSN":["1341-1357","1881-7122"],"issn-type":[{"value":"1341-1357","type":"print"},{"value":"1881-7122","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}