{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T16:45:13Z","timestamp":1758991513674},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2007,8,9]],"date-time":"2007-08-09T00:00:00Z","timestamp":1186617600000},"content-version":"vor","delay-in-days":39,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Occupational Health"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:p><jats:bold>High Pallidal T1 Signal is Rarely Observed in Obstructive Jaundice, but is Frequently Observed in Liver Cirrhosis: Sung\u2010Jo B<jats:sc>ang<\/jats:sc>, <jats:italic>et al<\/jats:italic>. Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, South Korea<\/jats:bold>\u2014Although high signal intensities in the globus pallidus are frequently observed in T1\u2010weighted magnetic resonance images (MRI) of patients with liver cirrhosis, it is unclear whether these increases are due to portal\u2010systemic shunt or obstruction of biliary excretion. We therefore studied pallidal signals in 18 cancer patients with bile duct obstruction and marked jaundice (&gt;10 mg\/dl). Patients who had fever, leukocytosis or liver cirrhosis were excluded to ensure that jaundice was due to bile duct obstruction. All patients showed a dilated intrahepatic duct on computed tomography (CT) scan. A high pallidal signal was observed in one of 18 biliary obstructive patients whereas high signals were highly prevalent in liver cirrhosis. A portal\u2010systemic shunt rather than an obstruction of biliary excretion may be responsible for the increased blood manganese concentrations and pallidal T1 signals in chronic liver diseases.<\/jats:p>","DOI":"10.1539\/joh.49.268","type":"journal-article","created":{"date-parts":[[2007,8,9]],"date-time":"2007-08-09T05:49:44Z","timestamp":1186638584000},"page":"268-272","source":"Crossref","is-referenced-by-count":6,"title":["High Pallidal T1 Signal is Rarely Observed in Obstructive Jaundice, but is Frequently Observed in Liver Cirrhosis"],"prefix":"10.1093","volume":"49","author":[{"given":"Sung\u2010Jo","family":"Bang","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Ulsan University Hospital, University of Ulsan College of Medicine South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seong Hoon","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Radiology Ulsan University Hospital, University of Ulsan 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