{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T18:13:21Z","timestamp":1790446401001,"version":"4.1.0"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2009,8,12]],"date-time":"2009-08-12T00:00:00Z","timestamp":1250035200000},"content-version":"vor","delay-in-days":42,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Occupational Health"],"published-print":{"date-parts":[[2009,7]]},"abstract":"<jats:sec><jats:label\/><jats:p><jats:bold>Higher Prevalence of Dry Symptoms in Skin, Eyes, Nose and Throat among Workers in Clean Rooms with Moderate Humidity: Shih\u2010Bin S<jats:sc>u<\/jats:sc>, <jats:italic>et al<\/jats:italic>. Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Taiwan<\/jats:bold><\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine whether working under relative humidity (RH) around 55 \u00b1 5% may lead to dry symptoms among workers in tropical regions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We recruited 3,154 Taiwanese workers who had no history of skin diseases and compared dry symptoms between clean room workers (RH around 55 \u00b1 5%) and other workers (RH around 65 \u00b1 5%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Clean room workers had higher prevalences of dry symptoms of the eye (odds ratio [OR]=1.62, 95% confidence interval [CI]: 1.40 to 1.86), nose and throat (OR=2.15, 95% CI: 1.66 to 2.79), and skin (OR=1.46, 95% CI: 1.23 to 1.73). In clean room workers, however, dry skin symptoms affected the palms (OR=1.72, 95% CI: 1.24 to 2.39), which are covered by gloves, more frequently than the face (OR=0.65, 95% CI: 0.45 to 0.94), which is exposed to the room air. We found working in clean rooms (adjusted OR [AOR]=1.38, 95% CI: 1.08 to 1.77), 24 to 30 yr of age (AOR=0.78, 95% CI: 0.62 to 0.99), family history of atopic diseases (AOR=1.75, 95% CI: 1.37 to 2.25), and skin moisturizer use (AOR=1.64, 95% CI: 1.30 to 2.06) were independent predictors of skin symptoms. In addition, working in clean rooms was an independent predictor of dry eye (AOR=1.30, 95% CI: 1.06 to 1.60) and dry nose and throat (AOR=1.70, 95% CI: 1.28 to 2.26) symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Whereas the humidity in such working environments is not very low, for workers living in a high humidity environment, the relatively low humidity may still cause dry symptoms of the eye, nose, and throat.<\/jats:p><\/jats:sec>","DOI":"10.1539\/joh.q8002","type":"journal-article","created":{"date-parts":[[2009,8,13]],"date-time":"2009-08-13T05:59:49Z","timestamp":1250143189000},"page":"364-369","source":"Crossref","is-referenced-by-count":21,"title":["Higher Prevalence of Dry Symptoms in Skin, Eyes, Nose and Throat among Workers in Clean Rooms with Moderate Humidity"],"prefix":"10.1093","volume":"51","author":[{"given":"Shih\u2010Bin","family":"Su","sequence":"first","affiliation":[{"name":"Department of Environmental and Occupational Health College of Medicine, National Cheng Kung University Taiwan"},{"name":"Tainan Science Park Clinic Chi\u2010Mei Medical Center Taiwan"},{"name":"Department of Biotechnology Southern Taiwan University Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bour\u2010Jr","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Environmental and Occupational Health College of Medicine, National Cheng Kung University Taiwan"},{"name":"Department of Occupational and Environmental Medicine National Cheng Kung University Hospital Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chien","family":"Tai","sequence":"additional","affiliation":[{"name":"Department of Biotechnology Southern Taiwan University Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsiu\u2010Fen","family":"Chang","sequence":"additional","affiliation":[{"name":"Health Center Chi\u2010Mei Optoelectronics Corporation Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"How\u2010Ran","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Environmental and Occupational Health College of Medicine, National Cheng Kung University Taiwan"},{"name":"Department of Occupational and Environmental Medicine National Cheng Kung University Hospital Taiwan"},{"name":"Sustainable Environment Research Center National Cheng Kung University Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2009,8,12]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1539\/joh.44.329"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1539\/joh.48.284"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-6-303"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1997.tb00330.x"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/41.1.37"},{"key":"e_1_2_1_7_1","first-page":"139","article-title":"Xerotic eczema\u2014Discussion on the environmental and occupational factors and demonstration of a case","volume":"19","author":"Su S\u2010B","year":"2004","journal-title":"Primary Med Care Family Med"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-005-0541-4"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00420-006-0133-4"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1539\/joh.45.133"},{"key":"e_1_2_1_11_1","unstructured":"Taiwan Central Weather Bureau.Monthly Mean Relative Humidity. 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