{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T05:23:38Z","timestamp":1736313818207,"version":"3.32.0"},"reference-count":54,"publisher":"Japan Society of Smooth Muscle Research","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Smooth Muscle Res","J. Smooth Muscle Res."],"published-print":{"date-parts":[[2005]]},"DOI":"10.1540\/jsmr.41.257","type":"journal-article","created":{"date-parts":[[2006,1,20]],"date-time":"2006-01-20T05:56:58Z","timestamp":1137736618000},"page":"257-270","source":"Crossref","is-referenced-by-count":5,"title":["Epithelium-dependent and -independent inhibitory effects of sivelestat, a neutrophil elastase inhibitor, on substance P-induced contraction of airway smooth muscle in lipopolysaccharide-treated guinea-pigs"],"prefix":"10.1540","volume":"41","author":[{"given":"Naomi","family":"Takayama","sequence":"first","affiliation":[{"name":"Department of Intensive and Critical Care Medicine, Dokkyo University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohsuke","family":"Uchida","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Dokkyo University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"435","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.97.10081892"},{"key":"2","doi-asserted-by":"crossref","unstructured":"Amitani, R., Wilson, R., Rutman, A., Read, R., Ward C., Burnett, D., Stockley R.A. and Cole, P.J. (1991). Effects of human neutrophil elastase and <i>Pseudomonas aeruginosa<\/i> proteinases on human respiratory epithelium. Am. J. Respir. Cell Mol. Biol. 4: 26-32.","DOI":"10.1165\/ajrcmb\/4.1.26"},{"key":"3","unstructured":"Bost, K.L., Breeding, S.A.L. and Pascual, D.W. (1992). Modulation of the mRNAs encoding substance P and its receptor in rat macrophages by LPS. Region. Immunol. 4: 105-112."},{"key":"4","unstructured":"Brigham, K.L. and Meyrick, B. (1986). Endotoxin and lung injury. Am. Rev. Respir. Dis. 133: 913-927."},{"key":"5","doi-asserted-by":"crossref","unstructured":"Carr, M.J., Schechter, N.M. and Undem, B.J. (2000). Trypsin-induced, neurokinin-mediated contraction of guinea pig bronchus. Am. J. Respir. Crit. Care Med. 162: 1662-1667.","DOI":"10.1164\/ajrccm.162.5.9912099"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1038\/18223"},{"key":"7","doi-asserted-by":"crossref","unstructured":"Dulon, S., Cande, C., Bunnett, N.W., Hollenberg, M.D., Chignard, M. and Pidard, D. (2003). Proteinase-activated receptor-2 and human lung epithelial cells. Disarming by neutrophil serine proteinases. Am. J. Respir. Cell Mol. Biol. 28: 339-346.","DOI":"10.1165\/rcmb.4908"},{"issue":"2","key":"8","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1111\/j.1476-5381.1989.tb11829.x","volume":"96","year":"1989","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1188","issn-type":"print"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(91)90636-P"},{"key":"10","doi-asserted-by":"crossref","unstructured":"Fujimoto, K., Kubo, K., Shinozaki, S., Okada, K., Matsuzawa, Y., Kobayashi, T. and Sugane, K. (1995). Neutrophil elastase inhibitor reduces asthmatic response in allergic sheep. Respir. Physiol. 100: 91-100.","DOI":"10.1016\/0034-5687(94)00123-H"},{"key":"11","doi-asserted-by":"crossref","unstructured":"Gaston, B., Drazen, J.M., Loscalzo, J. and Stamler, J.S. (1994). The biology of nitrogen oxides in the airways. Am. J. Respir. Crit. Care Med. 149: 538-551.","DOI":"10.1164\/ajrccm.149.2.7508323"},{"key":"12","doi-asserted-by":"crossref","unstructured":"Ghosh, M., Stewart, A., Tucker, D.E., Bonventre, J.V., Murphy, R.C. and Leslie, C.C. (2004). Role of cytosolic phospholipase A<sub>2<\/sub> in prostaglandin E<sub>2<\/sub> production by lung fibroblasts. Am. J. Respir. Cell Mol. Biol. 30: 91-100.","DOI":"10.1165\/rcmb.2003-0005OC"},{"key":"13","doi-asserted-by":"crossref","unstructured":"Gruetter, C.A., Childers, C.E., Bosserman, M.K., Lemke, S.M., Ball, J.G. and Valentovic, M.A. (1989). Comparison of relaxation induced by glyceryl trinitrate, isosorbide dinitrate, and sodium nitroprusside in bovine airways. Am. Rev. Respir. Dis. 139: 1192-1197.","DOI":"10.1164\/ajrccm\/139.5.1192"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(01)01191-8"},{"key":"15","unstructured":"Han, X., Fink, M.P., Uchiyama, T., Yang, R. and Delude, R.L. (2004). Increased iNOS activity is essential for pulmonary epithelial tight junction dysfunction in endotoxemic mice. Am. J. Physiol. 286: L259-L267."},{"key":"16","doi-asserted-by":"crossref","unstructured":"Haung, H.-Y. and Lai, Y.-L. (2003). Lipopoysaccharide induces preprotachykinin gene expression. Am. J. Respir. Cell Mol. Biol. 29: 606-612.","DOI":"10.1165\/rcmb.2002-0107OC"},{"issue":"5","key":"17","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1165\/ajrcmb\/9.5.568","volume":"9","year":"1993","ISSN":"https:\/\/id.crossref.org\/issn\/1044-1549","issn-type":"print"},{"issue":"4","key":"18","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1254\/fpj.103.141","volume":"103","author":"ITO YUSHI","year":"1994","ISSN":"https:\/\/id.crossref.org\/issn\/0015-5691","issn-type":"print"},{"key":"19","doi-asserted-by":"crossref","unstructured":"Jarreau, P.-H., D'ortho, M.-P., Boyer, V., Harf, A. and Macquin-Mavier, I. (1994). Effects of capsaicin on the airway responses to inhaled endotoxin in the guinea pig. Am. J. Respir. Crit. Care Med. 149: 128-133.","DOI":"10.1164\/ajrccm.149.1.8111569"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(92)94811-9"},{"key":"21","doi-asserted-by":"crossref","unstructured":"Kamikawa, Y. (1994). Neurogenic control of airway smooth muscle function. J. Pharmacol. Toxicol. 31: 207-213.","DOI":"10.1016\/1056-8719(94)90005-1"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.2332\/allergolint.54.99"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(02)02182-9"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1254\/fpj.122.151"},{"key":"25","doi-asserted-by":"crossref","unstructured":"Knight, D.A., Stewart, G.A. and Thompson, P.J. (1994). The respiratory epithelium and airway smooth muscle homeostasis: its relevance to asthma. Clin. Exp. Allergy 24: 698-706.","DOI":"10.1111\/j.1365-2222.1994.tb00980.x"},{"issue":"1","key":"26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1254\/fpj.102.1","volume":"102","author":"KONO SHIGEKATSU","year":"1993","ISSN":"https:\/\/id.crossref.org\/issn\/0015-5691","issn-type":"print"},{"key":"27","doi-asserted-by":"crossref","unstructured":"Koto, H., Aizawa, H., Takata, S., Inoue, H. and Hara, N. (1995). An important role of tachykinins in ozone-induced airway hyperresponsiveness. Am. J. Respir. Crit. Care Med. 151: 1763-1769.","DOI":"10.1164\/ajrccm.151.6.7767518"},{"issue":"4","key":"28","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1038\/sj.bjp.0702138","volume":"125","author":"KUO H-P","year":"1998","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1188","issn-type":"print"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(93)90831-2"},{"issue":"1","key":"30","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1476-5381.1991.tb12137.x","volume":"102","year":"1991","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1188","issn-type":"print"},{"key":"31","doi-asserted-by":"crossref","unstructured":"Li, X.Y., Donaldson, K. and MacNee, W. (1998). Lipopolysaccharide-induced alveolar epithelial permeability. Am. J. Respir. Crit. Care Med. 157: 1027-1033.","DOI":"10.1164\/ajrccm.157.4.9605080"},{"key":"32","doi-asserted-by":"crossref","unstructured":"Loeffler, B.S., Arden, W.A., Fiscus, R.R. and Lee, L.-Y. (1997). Involvement of tachykinins in endotoxin-induced airway hyperresponsiveness. Lung 175: 253-263.","DOI":"10.1007\/PL00007572"},{"issue":"2","key":"33","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0031-6997(24)01493-5","volume":"53","author":"MACFARLANE S R","year":"2001","ISSN":"https:\/\/id.crossref.org\/issn\/0031-6997","issn-type":"print"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-0115(97)00029-3"},{"key":"35","doi-asserted-by":"crossref","unstructured":"Matsumoto, K., Aizawa, H., Inoue, H., Koto, H., Nakano, H. and Hara, N. (1999) Role of neutrophil elastase in ozone-induced airway responses in guinea-pigs. Eur. Respir. J. 14: 1088-1094.","DOI":"10.1183\/09031936.99.14510889"},{"key":"36","doi-asserted-by":"crossref","unstructured":"Matsuse, T., Thomson, R.J., Chen, X.-R., Salari, H. and Schellenberg, R.R. (1991). Capsaicin inhibits airway hyperresponsiveness but not lipoxygenase activity or eosinophilia after repeated aerosolized antigen in guinea-pigs. Am. Rev. Respir. Dis. 144: 368-372.","DOI":"10.1164\/ajrccm\/144.2.368"},{"key":"37","doi-asserted-by":"crossref","unstructured":"Michel, O., Duchateau, J. and Sergysels, R. (1989). Effect of inhaled endotoxin on bronchial reactivity in asthmatic and normal subjects. J. Appl. Physiol. 66: 1059-1064.","DOI":"10.1152\/jappl.1989.66.3.1059"},{"key":"38","unstructured":"Mitchell, R.W. (1996). Regulation of smooth muscle contraction. In: Pulmonary and Critical Care Pharmacology and Therapeutics, ed. by A.R. Leff, McGraw-Hill, New York, pp. 191-197."},{"key":"39","doi-asserted-by":"crossref","unstructured":"Mollace, V., Muscoli, C., Masini, E., Cuzzocrea, S. and Salvemini, D. (2005). Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors. Pharmacol. Rev. 57: 217-252.","DOI":"10.1124\/pr.57.2.1"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-6147(00)01520-0"},{"issue":"1","key":"41","first-page":"76","volume":"238","year":"1986","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3565","issn-type":"print"},{"key":"42","unstructured":"Morrison, K.J., Gao, Y. and Vanhoutte, P.M. (1990). Epithelial modulation of airway smooth muscle. Am. J. Physiol. 258: L254-L262."},{"key":"43","unstructured":"Okajima, K., Harada, N., Uchiba, M. and Mori, M. (2004). Neutrophil elastase contributes to the development of ischemia-reperfusion-induced liver injury by decreasing endothelial production of prostacyclin in rats. Am. J. Physiol. 287: G1116-G1123."},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1016\/0306-3623(90)90587-C"},{"key":"45","doi-asserted-by":"crossref","unstructured":"Ricciardolo, F.L.M., Steinhoff, M., Amadesi, S., Guerrini, R., Tognetto, M., Trevisani, M., Creminon, C., Bertrand, C., Bunnett, N.W., Fabbri, L.M., Salvadori, S. and Geppetti, P. (2000). Presence and bronchomotor activity of protease-activated receptor-2 in guinea pig airways. Am. J. Respir. Crit. Care Med. 161: 1672-1680.","DOI":"10.1164\/ajrccm.161.5.9907133"},{"issue":"15","key":"46","doi-asserted-by":"crossref","first-page":"7240","DOI":"10.1073\/pnas.90.15.7240","volume":"90","year":"1993","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"2","key":"47","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1139\/y95-027","volume":"73","year":"1995","ISSN":"https:\/\/id.crossref.org\/issn\/0008-4212","issn-type":"print"},{"key":"48","doi-asserted-by":"crossref","unstructured":"Stuart-Smith, K. and Vanhoutte, P.M. (1987). Heterogeneity in the effects of epithelium removal in the canine bronchial tree. J. Appl. Physiol. 63: 2510-2515.","DOI":"10.1152\/jappl.1987.63.6.2510"},{"key":"49","doi-asserted-by":"crossref","unstructured":"Suzuki, T., Moraes, T.J., Vachon, E., Ginzberg, H.H., Huang, T.-T., Matthay, M.A., Hollenberg, M.D., Marshall, J., McCulloch, C.A.G., Abreu, M.T.H., Chow, C.-W. and Downey, G.P. (2005). Proteinase activated receptor-1 mediates elastase-induced apoptosis of human lung epithelial cells. Am. J. Respir. Cell Mol. Biol. 33: 231-247.","DOI":"10.1165\/rcmb.2005-0109OC"},{"key":"50","doi-asserted-by":"crossref","unstructured":"Suzuki, T., Wang, W., Lin, J.-T., Shirato, K., Mitsuhashi, H. and Inoue, H. (1996). Aerosolized human neutrophil elastase induces airway constriction and hyperresponsiveness with protection by intravenous pretreatment with half-length secretory leukoprotease inhibitor. Am. J. Respir. Crit. Care Med. 153: 1405-1411.","DOI":"10.1164\/ajrccm.153.4.8616573"},{"issue":"3","key":"51","first-page":"149","volume":"22","author":"UCHIDA K","year":"1995","ISSN":"https:\/\/id.crossref.org\/issn\/0385-5023","issn-type":"print"},{"key":"52","doi-asserted-by":"crossref","unstructured":"Veron, M., Guenon, I., Nenan, S., Emonds-Alt, X., Advenier, C., Lagente, V. and Boichot, E. (2004). Interactions of tachykinin receptor antagonists with lipopolysaccharide-induced airway inflammation in mice. Clin. Exp. Pharmacol. Physiol. 31: 634-640.","DOI":"10.1111\/j.1440-1681.2004.04061.x"},{"key":"53","doi-asserted-by":"crossref","unstructured":"Wu, Z.-X., Satterfield, B.E. and Dey, R.D. (2003). Substance P released from intrinsic airway neurons contributes to ozone-enhanced airway hyperresponsiveness in ferret trachea. J. Appl. Physiol. 95: 742-750.","DOI":"10.1152\/japplphysiol.00109.2003"},{"issue":"5","key":"54","first-page":"1009","volume":"36","year":"1995","ISSN":"https:\/\/id.crossref.org\/issn\/1039-9712","issn-type":"print"}],"container-title":["Journal of Smooth Muscle Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/jsmr\/41\/5\/41_5_257\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T08:03:24Z","timestamp":1736237004000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/jsmr\/41\/5\/41_5_257\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":54,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005]]}},"URL":"https:\/\/doi.org\/10.1540\/jsmr.41.257","relation":{},"ISSN":["0916-8737","1884-8796"],"issn-type":[{"type":"print","value":"0916-8737"},{"type":"electronic","value":"1884-8796"}],"subject":[],"published":{"date-parts":[[2005]]}}}