{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T03:29:31Z","timestamp":1790911771610,"version":"4.1.0"},"reference-count":27,"publisher":"Japan Society of Smooth Muscle Research","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Smooth Muscle Res","J. Smooth Muscle Res."],"published-print":{"date-parts":[[2011]]},"DOI":"10.1540\/jsmr.47.1","type":"journal-article","created":{"date-parts":[[2011,7,15]],"date-time":"2011-07-15T06:18:09Z","timestamp":1310710689000},"page":"1-10","source":"Crossref","is-referenced-by-count":8,"title":["Different effects of smoke from heavy and light cigarettes on the induction of bronchial smooth muscle hyperresponsiveness in rats"],"prefix":"10.1540","volume":"47","author":[{"given":"Hiroyasu","family":"Sakai","sequence":"first","affiliation":[{"name":"Department of Pharmacology, School of Pharmacy, Hoshi University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiko","family":"Fujita","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, School of Pharmacy, Hoshi University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayako","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, School of Pharmacy, Hoshi University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiko","family":"Chiba","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, School of Pharmacy, Hoshi University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junzo","family":"Kamei","sequence":"additional","affiliation":[{"name":"Department of Pathophysiology and Therapeutics, School of Pharmacy, Hoshi University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miwa","family":"Misawa","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, School of Pharmacy, Hoshi University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"435","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1124\/pr.56.4.2"},{"key":"2","unstructured":"Barnes, P.J. (2004). The role of anticholinergics in chronic obstructive pulmonary disease. Am. J. Med. 117: 24S–32S."},{"key":"3","unstructured":"Barrett, E.G., Wilder, J.A., March, T.H., Espindola, T. and Bice, D.E. (2002). Cigarette smoke-induced airway hyperresponsiveness is not dependent on elevated immunoglobulin and eosinophilic inflammation in a mouse model of allergic airway disease. Am. J. Respir. Crit. Care Med. 165: 1410–1418."},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1006\/taap.1995.1206"},{"key":"5","unstructured":"Ben-Jebria, A., Marthan, R., Rossetti, M., Savineau, J.P. and Ultman, J.S. (1993). Effect of in vitro exposure to acrolein on carbachol responses in rat trachealis muscle. Respir. Physiol. 93: 111–123."},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0702585"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2005-0177OC"},{"issue":"12","key":"8","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.1091\/mbc.8.12.2437","volume":"8","year":"1997","ISSN":"https:\/\/id.crossref.org\/issn\/1059-1524","issn-type":"print"},{"issue":"1","key":"9","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/S0022-3565(25)10687-3","volume":"274","year":"1995","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3565","issn-type":"print"},{"issue":"2","key":"10","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1091\/mbc.8.2.279","volume":"8","year":"1997","ISSN":"https:\/\/id.crossref.org\/issn\/1059-1524","issn-type":"print"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.3.1340"},{"key":"12","unstructured":"Gross, N.J. (2004). Tiotropium bromide. Chest 126: 1946–1953."},{"key":"13","unstructured":"Gross, N.J., Co, E. and Skorodin, M.S. (1989). Cholinergic bronchomotor tone in COPD. Estimates of its amount in comparison with that in normal subjects. Chest 96: 984–987."},{"issue":"13","key":"14","doi-asserted-by":"crossref","first-page":"8719","DOI":"10.1016\/S0021-9258(19)50337-4","volume":"267","year":"1992","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"key":"15","unstructured":"Leikauf, G.D., Leming, L.M., O’Donnell, J.R. and Doupnik, C.A. (1989). Bronchial responsiveness and inflammation in guinea pigs exposed to acrolein. J. Appl. Physiol. 66: 171–178."},{"key":"16","unstructured":"Lei, Y.H., Barnes, P.J. and Rogers, D.F. (1995). Mechanisms and modulation of airway plasma exudation after direct inhalation of cigarette smoke. Am. J. Respir. Crit. Care Med. 151: 1752–1762."},{"key":"17","unstructured":"Marthan, R., Roux, E. and Savineau, J.P. (1996). Human bronchial smooth muscle responsiveness after in vitro exposure to oxidizing pollutants. Cell Biol. Toxicol. 12: 245–249."},{"key":"18","unstructured":"Nisar, M., Earis, J.E., Pearson, M.G. and Calverley, P.M. (1992). Acute bronchodilator trials in chronic obstructive pulmonary disease. Am. Rev. Respir. Dis. 146: 555–559."},{"key":"19","unstructured":"Otto, B., Steusloff, A., Just, I., Aktories, K. and Pfitzer, G. (1996). Role of Rho proteins in carbachol-induced contractions in intact and permeabilized guinea-pig intestinal smooth muscle. J. Physiol. (Lond.) 496: 317–329."},{"key":"20","unstructured":"Petrescu, F., Voican, S.C. and Silosi, I. (2010). Tumor necrosis factor-alpha serum levels in healthy smokers and nonsmokers. Int. J. Chron. Obstruct. Pulmon. Dis. 5: 217–222."},{"key":"21","unstructured":"Sakai, H., Otogoto, S., Chiba, Y., Abe, K. and Misawa, M. (2004). Involvement of p42\/44 MAPK and RhoA protein in augmentation of ACh-induced bronchial smooth muscle contraction by TNF-alpha in rats. J. Appl. Physiol. 97: 2154–2159."},{"key":"22","unstructured":"Tashkin, D.P., Altose, M.D., Bleecker, E.R., Connett, J.E., Kanner, R.E., Lee, W.W. and Wise, R. (1992). The lung health study: airway responsiveness to inhaled methacholine in smokers with mild to moderate airflow limitation. The Lung Health Study Research Group. Am. Rev. Respir. Dis. 145: 301–310."},{"key":"23","unstructured":"Tashkin, D.P., Altose, M.D., Connett, J.E., Kanner, R.E., Lee, W.W. and Wise, R.A. (1996). Methacholine reactivity predicts changes in lung function over time in smokers with early chronic obstructive pulmonary disease. The Lung Health Study Research Group. Am. J. Respir. Crit. Care Med. 153: 1802–1811."},{"key":"24","unstructured":"Tashkin, D.P., Simmons, M.S., Chang, P., Liu, H. and Coulson, A.H. (1993). Effects of smoked substance abuse on nonspecific airway hyperresponsiveness. Am. Rev. Respir. Dis. 147: 97–103."},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.00427"},{"key":"26","unstructured":"Wu, Z.X. and Lee, L.Y. (1999). Airway hyperresponsiveness induced by chronic exposure to cigarette smoke in guinea pigs: role of tachykinins. J. Appl. Physiol. 87: 1621–1628."},{"key":"27","unstructured":"Xu, L.J., Dandurand, R.J., Lei, M. and Eidelman, D.H. (1993). Airway hyperresponsiveness in cigarette smoke-exposed rats. Lung 171: 95–107."}],"container-title":["Journal of Smooth Muscle Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/jsmr\/47\/1\/47_1_1\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T03:15:49Z","timestamp":1741317349000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/jsmr\/47\/1\/47_1_1\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1540\/jsmr.47.1","relation":{},"ISSN":["0916-8737","1884-8796"],"issn-type":[{"value":"0916-8737","type":"print"},{"value":"1884-8796","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}