{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T15:08:38Z","timestamp":1768403318486,"version":"3.49.0"},"reference-count":0,"publisher":"Romanian Society of Gastroenterology and Hepatology","license":[{"start":{"date-parts":[[2020,1,8]],"date-time":"2020-01-08T00:00:00Z","timestamp":1578441600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JGLD"],"abstract":"<jats:p>In this session diverse critical issues in diverticular disease were considered, including \u201cIn or outpatient management of uncomplicated diverticulitis?\u201d, \u201cSegmental colitis associated with diverticulosis: what is it?\u201dand \u201cDiverticular inflammation is a risk factor for colorectal cancer?\u201d. The conclusions drawn are outlined in the statements but in summary, outpatient management is safe in selected patients, as long as correct diagnosis and stage are assured, and this can allow a cost effective treatment. Non-antibiotic management is also safe but should be confined as an outpatient treatment in carefully selected patients.\u00a0\r\nSegmental colitis associated with diverticulosis (SCAD) is a defined pathological entity (only diagnosed on biopsy) characterized by an inflammatory bowel disease-like pathology, occurring principally in the sigmoid colon, with rectal and right colon sparing.\u00a0 The pathogenesis is unclear but may include a genetic predisposition, microbiome alteration and ischaemia. Treatment can last months, and depends on severity, options include antibiotics, 5 ASA and probiotics for mild cases. Severe disease needs systemic steroids or even anti TNF\u03b1 treatment.\u00a0\r\nWhether diverticular inflammation is a risk factor for colorectal cancer was debated and the conclusion that within the first eighteen months of diagnosis of diverticular disease associations with cancer are found, likely due to similar symptoms and misclassification of disease. After that time, diverticular disease does not increase the risk of colorectal cancer. Therefore, this is recommended to exclude cancer with imaging and colonoscopy after healing of the first episode of diverticulitis.<\/jats:p>","DOI":"10.15403\/jgld-557","type":"journal-article","created":{"date-parts":[[2020,1,10]],"date-time":"2020-01-10T12:07:28Z","timestamp":1578658048000},"page":"35-38","source":"Crossref","is-referenced-by-count":1,"title":["Critical Issues on Diverticular Disease"],"prefix":"10.15403","volume":"28","author":[{"given":"Neil","family":"Stollman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcello","family":"Picchio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastiano","family":"Biondo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adi","family":"Lahat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan L.","family":"Dumitrascu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaroslaw","family":"Regula","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marjorie M.D.","family":"Walker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6121","published-online":{"date-parts":[[2020,1,8]]},"container-title":["Journal of Gastrointestinal and Liver Diseases"],"original-title":[],"deposited":{"date-parts":[[2020,1,10]],"date-time":"2020-01-10T12:07:36Z","timestamp":1578658056000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jgld.ro\/jgld\/public\/public\/Supplements\/supplement_2019_4_557.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,8]]},"references-count":0,"URL":"https:\/\/doi.org\/10.15403\/jgld-557","relation":{},"ISSN":["1842-1121","1841-8724"],"issn-type":[{"value":"1842-1121","type":"electronic"},{"value":"1841-8724","type":"print"}],"subject":[],"published":{"date-parts":[[2020,1,8]]}}}