{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T06:29:05Z","timestamp":1761719345484,"version":"3.41.0"},"reference-count":0,"publisher":"Romanian Society of Gastroenterology and Hepatology","issue":"2","license":[{"start":{"date-parts":[[2025,6,28]],"date-time":"2025-06-28T00:00:00Z","timestamp":1751068800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JGLD"],"abstract":"<jats:p>Background and Aims: Lichenoid esophagitis (LichE) is rarely encountered by gastrointestinal endoscopists. Using a large nationwide database of clinicopathological records, the demographic and clinical characteristics of patients with LichE were compared to patients with lymphocytic esophagitis (LyE) and eosinophilic esophagitis (EoE).\nMethods: In a case-control study, cases with a diagnosis of LichE, LyE, or EoE were compared to a control population of all patients without these 3 conditions. In addition to histopathology, patients\u2019 demographics, clinical presentation, and gastrointestinal comorbidities were considered. Statistical significance was assessed using odds ratios (OR) and 95% confidence intervals (95%CI).\nResults: Among 967,773 unique patients with esophageal biopsies, LichE was found in 511 (0.05%), LyE in 1,786 (0.18%), EoE in 56,474 (5.84%), and none of these 3 diagnoses in a control population of 909,002 patients. LichE patients were significantly older, and EoE patients were significantly younger than the control population (p&lt;0.0001). LichE and LyE significantly prevailed in females (OR=1.69; 95%CI: 1.40-2.04 and 1.34; 1.22-1.47, respectively). EoE was significantly less common in females (OR=0.49; 95%CI: 0.48-0.49). All 3 types of esophagitis were significantly less common among Hispanics, with their respective ORs of 0.70 (95%CI: 0.50-0.98), 0.83 (95%CI: 0.70-0.98), and 0.55 (95%CI: 0.53-0.57). EoE was also less common in persons of East and South Asian ancestry, with respective ORs of 0.52 (95%CI: 0.47-0.56) and 0.66 (95%CI: 0.56-0.76).\nConclusions: Increasing clinical awareness of LichE may enhance its clinico-pathological recognition, clarify its natural history, and ultimately lead to more effective clinical management.<\/jats:p>","DOI":"10.15403\/jgld-6048","type":"journal-article","created":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T22:32:37Z","timestamp":1751063557000},"page":"157-162","source":"Crossref","is-referenced-by-count":1,"title":["Lichenoid Esophagitis: A Clinicopathological Comparison with Lymphocytic and Eosinophilic Esophagitis"],"prefix":"10.15403","volume":"34","author":[{"given":"Salima","family":"Haque","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. Maral K","family":"Mohammadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anuradha","family":"Singhal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amnon","family":"Sonnenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9482-4163","authenticated-orcid":false,"given":"Robert Maximilian","family":"Genta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0679-0563","authenticated-orcid":false,"given":"Massimo","family":"Rugge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6121","published-online":{"date-parts":[[2025,6,28]]},"container-title":["Journal of Gastrointestinal and Liver Diseases"],"original-title":[],"link":[{"URL":"https:\/\/jgld.ro\/jgld\/index.php\/jgld\/article\/download\/6048\/2191","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jgld.ro\/jgld\/index.php\/jgld\/article\/download\/6048\/2191","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T22:32:37Z","timestamp":1751063557000},"score":1,"resource":{"primary":{"URL":"https:\/\/jgld.ro\/jgld\/index.php\/jgld\/article\/view\/6048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,28]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,6,28]]}},"URL":"https:\/\/doi.org\/10.15403\/jgld-6048","relation":{},"ISSN":["1842-1121","1841-8724"],"issn-type":[{"value":"1842-1121","type":"electronic"},{"value":"1841-8724","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6,28]]}}}