{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T16:16:31Z","timestamp":1788020191866,"version":"build-2784847793"},"reference-count":0,"publisher":"Romanian Society of Gastroenterology and Hepatology","license":[{"start":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:00:00Z","timestamp":1787961600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JGLD"],"abstract":"<jats:p>Acute necrotizing pancreatitis is a severe condition associating with high morbidity and mortality. In most cases, supportive therapy is the only available therapeutic option. Herein, we report a case of a 29-year-old male who presented with severe acute necrotizing pancreatitis caused by hypertriglyceridemia, who consequently developed acute respiratory distress syndrome and multi-organ failure. We used an off-label C-reactive protein apheresis to target the sterile inflammatory reactions additional to optimal supportive therapy with invasive ventilation, prone positioning, continuous veno-venous hemodialysis using a CytoSorb\u2122 particle filter, antibiotics, vasopressors, and fluids. After 18 days of intensive care treatment and 11 days of normal care treatment, the patient could be discharged alive.<\/jats:p>","DOI":"10.15403\/jgld-7040","type":"journal-article","created":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T15:22:30Z","timestamp":1788016950000},"source":"Crossref","is-referenced-by-count":0,"title":["C-reactive Protein Apheresis: A Novel Treatment Approach in Acute Necrotising Pancreatitis"],"prefix":"10.15403","author":[{"given":"Felix","family":"G\u00f6tzinger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Kunz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Mahfoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"B\u00f6hm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Link","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"6121","published-online":{"date-parts":[[2026,8,29]]},"container-title":["Journal of Gastrointestinal and Liver Diseases"],"original-title":[],"link":[{"URL":"https:\/\/jgld.ro\/jgld\/index.php\/jgld\/article\/download\/7040\/2381","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jgld.ro\/jgld\/index.php\/jgld\/article\/download\/7040\/2381","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T15:22:31Z","timestamp":1788016951000},"score":1,"resource":{"primary":{"URL":"https:\/\/jgld.ro\/jgld\/index.php\/jgld\/article\/view\/7040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,29]]},"references-count":0,"URL":"https:\/\/doi.org\/10.15403\/jgld-7040","relation":{},"ISSN":["1842-1121","1841-8724"],"issn-type":[{"value":"1842-1121","type":"electronic"},{"value":"1841-8724","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,29]]}}}