{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T08:01:58Z","timestamp":1748592118949,"version":"3.40.5"},"reference-count":40,"publisher":"American Academy of Pediatrics (AAP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,11,1]]},"abstract":"<jats:sec><jats:title>Objectives:<\/jats:title><jats:p>To describe readmissions among children hospitalized with H1N1 (influenza subtype, hemagglutinin1, neuraminidase 1) pandemic influenza and secondarily to determine the association of oseltamivir during index hospitalization with readmission.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>We reviewed data from 42 freestanding children\u2019s hospitals contributing to the Pediatric Health Information System from May through December 2009 when H1N1 was the predominant influenza strain. Children were divided into 2 groups by whether they experienced complications of influenza during index hospitalization. Primary outcome was readmission at 3, 7, and 30 days among both patient groups. Secondary outcome was the association of oseltamivir treatment with readmission.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>The study included 8899 children; 6162 patients had uncomplicated index hospitalization, of whom 3808 (61.8%) received oseltamivir during hospitalization, and 2737 children had complicated influenza, of whom 1055 (38.5%) received oseltamivir. Median 3-, 7-, and 30-day readmission rates were 1.6%, 2.5%, and 4.7% for patients with uncomplicated index hospitalizations and 4.3%, 5.8%, and 10.3% among patients with complicated influenza. The 30-day readmission rates did not differ by treatment group among patients with uncomplicated influenza; however, patients with complicated index hospitalizations who received oseltamivir had lower all-cause 30-day readmissions than untreated patients. The most common causes of readmission were pneumonia and asthma exacerbations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Oseltamivir use for hospitalized children did not decrease 30-day readmission rates in children after uncomplicated index hospitalization but was associated with a lower 30-day readmission rate among children with complicated infections during the 2009 H1N1 pandemic. Readmission rates for children who had complicated influenza infection during index hospitalizations are high.<\/jats:p><\/jats:sec>","DOI":"10.1542\/hpeds.2014-0045","type":"journal-article","created":{"date-parts":[[2014,10,31]],"date-time":"2014-10-31T09:02:08Z","timestamp":1414746128000},"page":"348-358","source":"Crossref","is-referenced-by-count":11,"title":["Hospital Readmissions Among Children With H1N1 Influenza Infection"],"prefix":"10.1542","volume":"4","author":[{"given":"Thomas V.","family":"Brogan","sequence":"first","affiliation":[{"name":"Seattle Children\u2019s Hospital, and Department of Pediatrics, Division of Critical Care Medicine, University of Washington School of Medicine, Seattle, Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Hall","sequence":"additional","affiliation":[{"name":"Children\u2019s Hospital Association, Overland Park, Kansas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marion R.","family":"Sills","sequence":"additional","affiliation":[{"name":"University of Colorado School of Medicine and Children\u2019s Hospital Colorado, Aurora, Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evan S.","family":"Fieldston","sequence":"additional","affiliation":[{"name":"Perelman School of Medicine at the University of Pennsylvania and The Children\u2019s Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harold K.","family":"Simon","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine and Children\u2019s Healthcare of Atlanta, Atlanta, Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael B.","family":"Mundorff","sequence":"additional","affiliation":[{"name":"Department of Systems Improvement, Children\u2019s Primary Hospital, Salt Lake City, Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel B.","family":"Fagbuyi","sequence":"additional","affiliation":[{"name":"The George Washington University School of Medicine, and Children\u2019s National Medical Center, Washington, District of Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samir S.","family":"Shah","sequence":"additional","affiliation":[{"name":"Divisions of Infectious Diseases and Hospital Medicine, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio"},{"name":"Department of Pediatrics and Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2014,11,1]]},"reference":[{"issue":"15","key":"2021120908222154000_B1","first-page":"400","article-title":"Swine influenza A (H1N1) infection in two children\u2014Southern California, March\u2013April 2009","volume":"58","author":"Centers for Disease Control and Prevention","year":"2009","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"11","key":"2021120908222154000_B2","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1001\/jama.292.11.1333","article-title":"Influenza-associated hospitalizations in the United States","volume":"292","author":"Thompson","year":"2004","journal-title":"JAMA"},{"issue":"20","key":"2021120908222154000_B3","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1056\/NEJMoa0906695","article-title":"2009 Pandemic Influenza A (H1N1) Virus Hospitalizations Investigation Team. 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