{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T08:09:08Z","timestamp":1777363748960,"version":"3.51.4"},"reference-count":31,"publisher":"American Academy of Pediatrics (AAP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,3,1]]},"abstract":"\n BACKGROUND:<\/jats:title>\n Although the utility of universal newborn hearing screening is undisputed, testing protocols vary. In particular, the impact of the infant\u2019s age at the time of automated auditory brainstem response (AABR) screening has not been well studied.<\/jats:p>\n <\/jats:sec>\n \n METHODS:<\/jats:title>\n We conducted a retrospective review of newborn hearing screening data in 6817 low-risk, term and late-preterm newborns at our large, urban, academic medical center for a 1-year period to analyze the impact of age and other factors on the screening failure rate and referral for diagnostic testing.<\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n AABR screening failure rates decreased with postnatal age over the first 48 hours; 13.3% failed at &lt;24 hours versus 3.8% at \u226548 hours (P &lt; .0001). Infants who were initially tested at \u226536 hours failed repeat testing more often than those who were tested at &lt;36 hours (11.5% vs 18.9%; P = .03). Other factors that were associated with failure included being a boy and of a race other than white. Sensorineural hearing loss (SNHL) was diagnosed in 18.6% of infants who failed their final screening at \u226548 hours compared with 2.8% of those whose final screening occurred earlier (P = .03). SNHL was more likely in infants who failed their first screening bilaterally (21.2%) than unilaterally (4.4%); P = .03).<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS:<\/jats:title>\n Among healthy newborns, delaying AABR screening in the first 48 hours minimized failure rates. SNHL was 6 times as likely in infants who failed their final screening at \u226548 hours compared with those who were screened at &lt;48 hours of age. In our study, we offer guidance for nursery directors and audiologists who determine hearing screening protocols and counsel families about results.<\/jats:p>\n <\/jats:sec>","DOI":"10.1542\/hpeds.2017-0060","type":"journal-article","created":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T09:30:27Z","timestamp":1519896627000},"page":"141-147","source":"Crossref","is-referenced-by-count":8,"title":["Age and Other Factors Affecting the Outcome of AABR Screening in Neonates"],"prefix":"10.1542","volume":"8","author":[{"given":"Lise Carolyn","family":"Johnson","sequence":"first","affiliation":[{"name":"Department of Pediatric Newborn Medicine, Brigham and Women\u2019s Hospital, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret","family":"Toro","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Vishnja","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arielle","family":"Berish","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bianca","family":"Mills","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhigang","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Newborn Medicine, Brigham and Women\u2019s Hospital, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellice","family":"Lieberman","sequence":"additional","affiliation":[{"name":"Department of Pediatric Newborn Medicine, Brigham and Women\u2019s Hospital, Boston, 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