{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:56:13Z","timestamp":1787320573312,"version":"build-2736575974"},"reference-count":37,"publisher":"American Academy of Pediatrics (AAP)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,11,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVES:<\/jats:title>\n                    <jats:p>Many children with cancer have repeated and prolonged hospitalizations, and in-hospital sleep disruption may negatively affect outcomes. Our objective for this study was to characterize sleep quality and quantity in hospitalized children with cancer by using parental surveys and actigraphy, to evaluate the association between subjective and objective sleep measures, and to describe hospital-associated risk factors related to poor sleep.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>Cross-sectional study of children aged 0 to 18 years old admitted to a pediatric oncology ward. Parents completed a baseline sleep questionnaire describing their child\u2019s sleep at home before hospitalization, followed by daily questionnaires describing their child\u2019s sleep for up to 3 nights while in the hospital. A subgroup of children aged 5 to 18 years wore actigraphs during the same time period. Demographic and clinical data were extracted from the electronic medical record. The primary outcome was inadequate sleep, defined by the total sleep duration adjusted for age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>Among 56 participants over 135 hospital nights, 66% (n = 37) reported inadequate sleep. Actigraphy was completed on 39 nights (29%), with a median total sleep time of 477 (interquartile range 407\u2013557) minutes. There was a strong correlation between subjective questionnaire measures and actigraphic measures (r = 0.76). No patient-specific demographic factors were related to inadequate sleep. A multivariable model indicated the following hospital-related factors were associated with inadequate sleep: noise (adjusted odds ratio [aOR] 3.0; confidence interval [CI] 1.2\u20137.7), alarms (aOR 3.1; CI 1.2\u20138.3), child\u2019s worries (aOR 2.8; CI 1.1\u20137.2), and receipt of benzodiazepines (aOR 2.9; CI 1.2\u20137.5).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>A majority of children experienced inadequate sleep during hospitalization. Subjective report of sleep duration correlated well with objective measures of sleep by actigraphy. Several potentially modifiable factors were independently associated with poor sleep. Further interventional studies are required to test approaches to optimize sleep in hospitalized children with cancer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1542\/hpeds.2020-0101","type":"journal-article","created":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T09:20:10Z","timestamp":1604308810000},"page":"969-976","source":"Crossref","is-referenced-by-count":31,"title":["Sleep in Hospitalized Children With Cancer: A Cross-Sectional Study"],"prefix":"10.1542","volume":"10","author":[{"given":"Chani","family":"Traube","sequence":"first","affiliation":[{"name":"Departments of Pediatrics,"},{"name":"Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynne","family":"Rosenberg","sequence":"additional","affiliation":[{"name":"Departments of 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