{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T12:28:27Z","timestamp":1769171307615,"version":"3.49.0"},"reference-count":13,"publisher":"American Academy of Pediatrics (AAP)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,9,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVES:<\/jats:title>\n                  <jats:p>No clear guidelines exist for the management of infants \u226460 days old with urinary tract infection (UTI), although this condition represents a significant percentage of serious bacterial infection in this age group. We examined patterns of UTI management in infants \u226460 days at a tertiary care children\u2019s hospital and hypothesized that younger infants would be hospitalized longer.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>METHODS:<\/jats:title>\n                  <jats:p>We reviewed electronic health records of infants age \u226460 days with diagnostic codes of UTI or fever hospitalized from January 2013 to January 2017 with urine culture obtained and UTI diagnosis documented. Outcomes were duration of parenteral antibiotic therapy, length of stay (LOS), and hospital readmission.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS:<\/jats:title>\n                  <jats:p>One hundred ninety-three infants met criteria. Median age at admission was 37 days (interquartile range [IQR]: 22\u201348). Median duration of parenteral antibiotics was 59 hours (IQR 43\u2013114) and median LOS was 71 hours (IQR 57\u2009127). Infants age \u226428 days, with fever duration \u226524 hours, irritability or lethargy on initial examination, and bacteremia received longer parenteral therapy and had longer LOS. In multivariate analysis, age, irritability or lethargy, and presence of bacteremia remained independently related to parenteral therapy duration and LOS.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS:<\/jats:title>\n                  <jats:p>In young infants with UTI, patients aged \u226428 days had longer duration of IV antibiotic therapy and LOS, independent of other clinical characteristics of their illness. The duration of parenteral therapy and LOS was relatively short, although significant variability still existed.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1542\/hpeds.2020-0178","type":"journal-article","created":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T13:15:17Z","timestamp":1598966117000},"page":"792-796","source":"Crossref","is-referenced-by-count":8,"title":["Urinary Tract Infection in Young Infants: Practice Patterns in Evaluation and Treatment"],"prefix":"10.1542","volume":"10","author":[{"given":"Sheila","family":"Swartz","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Kolinski","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Hadjiev","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erica","family":"Chou","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cameron","family":"Malone","sequence":"additional","affiliation":[{"name":"Department of Medicine, Aurora St Luke\u2019s Medical Center, Milwaukee, Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ke","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Havens","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin; and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2020,9,1]]},"reference":[{"issue":"3","key":"2021120817582047500_B1","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1542\/peds.2011-1330","article-title":"Urinary tract infection: clinical practice guideline for the diagnosis and management of the initial UTI in febrile infants and children 2 to 24 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