{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:58:17Z","timestamp":1790816297431,"version":"4.1.0"},"reference-count":11,"publisher":"American Academy of Pediatrics (AAP)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,1]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>The American Academy of Pediatrics suggests 2 approaches for neonates born to blood group O mothers: routine cord blood type and Coombs testing or clinical surveillance with selective testing for jaundiced neonates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To determine whether routine cord blood testing reduces neonatal intensive care unit (NICU) admissions for hyperbilirubinemia because of ABO incompatibility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>STUDY DESIGN<\/jats:title>\n                    <jats:p>This retrospective pre-post study analyzed all births at one urban, university-affiliated hospital in Pennsylvania from 2007 to 2020. The hospital transitioned from routine cord blood evaluation (2007\u20132012, period A) to selective evaluation (2013\u20132020, period B). The primary outcome was transfer from the well baby nursery (WBN) to the NICU for severe hyperbilirubinemia because of ABO incompatibility. Secondary outcomes included peak bilirubin at or above exchange threshold and intravenous immunoglobulin (IVIG) treatment. Chi-square or Fisher exact tests were used to compare differences in outcomes as a percentage of all births across the 2 time periods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Of 29\u2009207 births (12\u2009291 in period A; 16\u2009916 in period B), a total of 1581 neonates were transferred to the NICU from WBN (5.2% in period A vs 5.5% in period B; P\u2009=\u2009.19). Transfer for hyperbilirubinemia because of ABO incompatibility was more frequent in period B than A (0.11% vs 0.03%; P\u2009=\u2009.01). During period B, more infants had bilirubin at or above exchange transfusion level (0.06% vs 0.01%; P\u2009=\u2009.02) and received IVIG (0.06% vs 0%; P\u2009=\u2009.002).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>For infants born to blood group O mothers, routine cord blood evaluation vs selective evaluation may prevent severe hyperbilirubinemia requiring NICU transfer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1542\/hpeds.2025-009165","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:02:36Z","timestamp":1785196956000},"page":"e777-e780","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Utility of Routine Umbilical Cord Blood Screening for ABO Incompatibility: A Single-Center Observational Study"],"prefix":"10.1542","volume":"16","author":[{"given":"Paige","family":"Kube","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Division of Neonatology, Nemours Children\u2019s Health, Thomas Jefferson University, and Nemours Pediatric Health, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David L.","family":"Carola","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neonatology, Nemours Children\u2019s Health, Thomas Jefferson University, and Nemours Pediatric Health, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neera","family":"Goyal","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neonatology, Nemours Children\u2019s Health, Thomas Jefferson University, and Nemours Pediatric Health, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zubair H.","family":"Aghai","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neonatology, Nemours Children\u2019s Health, Thomas Jefferson University, and Nemours Pediatric Health, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2026,7,28]]},"reference":[{"issue":"3","key":"2026093020002555200_r1","doi-asserted-by":"crossref","first-page":"e2022058859","DOI":"10.1542\/peds.2022-058859","article-title":"Clinical practice guideline revision: management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation","volume":"150","author":"Kemper","year":"2022","journal-title":"Pediatrics."},{"issue":"1","key":"2026093020002555200_r2","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1542\/peds.114.1.297","article-title":"Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation","volume":"114","author":"American Academy of Pediatrics Subcommittee on Hyperbilirubinemia","year":"2004","journal-title":"Pediatrics."},{"issue":"10","key":"2026093020002555200_r3","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1001\/archpedi.1995.02170230101015","article-title":"Wasted health care dollars. 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