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When caring for these infants, practitioners need to shift from the acute care ventilation strategies that use frequent blood gases and support adjustments designed to minimize exposure to positive pressure. Infants with severe BPD benefit from a chronic care model that uses less frequent ventilator adjustments and provides the level of positive support that will achieve the longer-term goal of ongoing lung growth and repair.<\/jats:p>","DOI":"10.1542\/neo.21-4-e226","type":"journal-article","created":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T09:24:37Z","timestamp":1585733077000},"page":"e226-e237","source":"Crossref","is-referenced-by-count":48,"title":["Ventilation Strategies in Severe Bronchopulmonary Dysplasia"],"prefix":"10.1542","volume":"21","author":[{"given":"Kathleen","family":"Gibbs","sequence":"first","affiliation":[{"name":"Divisions of Neonatology and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik A.","family":"Jensen","sequence":"additional","affiliation":[{"name":"Divisions of Neonatology and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stamatia","family":"Alexiou","sequence":"additional","affiliation":[{"name":"Pulmonology, Department of Pediatrics, Children\u2019s Hospital of Philadelphia and The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Munson","sequence":"additional","affiliation":[{"name":"Divisions of Neonatology and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huayan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Divisions of Neonatology and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2020,4,1]]},"reference":[{"issue":"3","key":"2021121001313299000_B1","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1542\/peds.2009-2959","article-title":"Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network","volume":"126","author":"Stoll","year":"2010","journal-title":"Pediatrics"},{"issue":"2","key":"2021121001313299000_B2","doi-asserted-by":"crossref","first-page":"e143676","DOI":"10.1001\/jamapediatrics.2014.3676","article-title":"Hospital variation and risk factors for bronchopulmonary dysplasia in a population-based cohort","volume":"169","author":"Lapcharoensap","year":"2015","journal-title":"JAMA Pediatr"},{"issue":"7","key":"2021121001313299000_B3","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1056\/NEJMoa1605566","article-title":"Survival and neurodevelopmental outcomes among periviable infants","volume":"376","author":"Younge","year":"2017","journal-title":"N Engl J Med"},{"issue":"7","key":"2021121001313299000_B4","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1056\/NEJM196702162760701","article-title":"Pulmonary disease following respirator therapy of hyaline-membrane disease. 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