{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:15:12Z","timestamp":1768436112285,"version":"3.49.0"},"reference-count":14,"publisher":"American Academy of Pediatrics (AAP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,1]]},"abstract":"<jats:p>Intestinal atresia is one of the most common causes of bowel obstruction in newborns. Unfortunately, this diagnosis is often missed or delayed in extremely preterm infants because of complications of prematurity including feeding intolerance and necrotizing enterocolitis. Here we report 2 cases of jejunoileal atresia in extremely preterm infants who were diagnosed beyond 30 days of age. Case 1 had jejunoileal atresia type IIIa, whereas case 2 had type IV jejunoileal atresia complicated by short bowel syndrome. Ideally, intestinal atresia should be diagnosed as early as possible in a patient\u2019s hospital course to attain full enteral feedings earlier and avoid prolonged hospitalization. Planned surgical intervention prior to the development of sepsis or bowel perforation is associated with better outcomes. Ultimately, this report serves as a reminder to physicians that intestinal atresia remains an important differential for infants, including preterm infants, with feeding intolerance in the first days to weeks of age.<\/jats:p>","DOI":"10.1542\/neo.24-5-e300","type":"journal-article","created":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T03:17:19Z","timestamp":1682911039000},"page":"e300-e305","source":"Crossref","is-referenced-by-count":2,"title":["Does Preterm Status Hinder the Timely Diagnosis of Intestinal Atresia?"],"prefix":"10.1542","volume":"24","author":[{"given":"Youness","family":"Tolaymat","sequence":"first","affiliation":[{"name":"*Division of Neonatology, Department of Pediatrics, University of Florida, Gainesville, FL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raechel","family":"Irons","sequence":"additional","affiliation":[{"name":"\u2020Department of Pediatrics, University of Florida, Gainesville, FL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janice A.","family":"Taylor","sequence":"additional","affiliation":[{"name":"\u2021Department of Surgery, University of Florida, Gainesville, FL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dhanashree","family":"Rajderkar","sequence":"additional","affiliation":[{"name":"\u00a7Department of Radiology, University of Florida, Gainesville, FL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Cacho","sequence":"additional","affiliation":[{"name":"*Division of Neonatology, Department of Pediatrics, University of Florida, Gainesville, FL"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2023,5,1]]},"reference":[{"issue":"13","key":"2023050103171040300_B1","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1002\/pd.1886","article-title":"Small intestinal atresia in a defined population: occurrence, prenatal diagnosis and survival","volume":"27","author":"Hemming","year":"2007","journal-title":"Prenat Diagn"},{"issue":"5","key":"2023050103171040300_B2","doi-asserted-by":"crossref","first-page":"F353","DOI":"10.1136\/fetalneonatal-2011-300631","article-title":"Epidemiology of small intestinal atresia in Europe: a register-based study","volume":"97","author":"Best","year":"2012","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"6","key":"2023050103171040300_B3","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1111\/ped.12359","article-title":"Population-based study of esophageal and small intestinal atresia\/stenosis","volume":"56","author":"Takahashi","year":"2014","journal-title":"Pediatr Int"},{"issue":"6","key":"2023050103171040300_B4","first-page":"939","article-title":"Congenital atresia of the intestine: pathogenesis and treatment","volume":"154","author":"Santulli","year":"1961","journal-title":"Ann Surg"},{"issue":"6","key":"2023050103171040300_B5","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/BF02616944","article-title":"Investigations into the etiology of congenital atresia of the colon","volume":"7","author":"Louw","year":"1964","journal-title":"Dis Colon Rectum"},{"issue":"1","key":"2023050103171040300_B6","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1093\/aje\/155.1.26","article-title":"Maternal medication use and risks of gastroschisis and small intestinal atresia","volume":"155","author":"Werler","year":"2002","journal-title":"Am J Epidemiol"},{"issue":"3","key":"2023050103171040300_B7","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1097\/01.EDE.0000059226.36219.DE","article-title":"Association of vasoconstrictive exposures with risks of gastroschisis and small intestinal atresia","volume":"14","author":"Werler","year":"2003","journal-title":"Epidemiology"},{"key":"2023050103171040300_B8","unstructured":"Millar\u2008AJW, Gosche\u2008JR. Lakhoo\u2008K. Intestinal atresia and stenosis. In: Ameh\u2008EA, Bickler\u2008SW, Lakhoo\u2008K, Nwomeh\u2008BC, Poenaru\u2008D, eds. Paediatric Surgery: A Comprehensive Text for Africa. 2011Accessed February 18, 2023. http:\/\/www.surgicalneed.nl\/wp-content\/uploads\/2016\/08\/help_pedsurgeryafricavolume02.pdf."},{"issue":"1","key":"2023050103171040300_B9","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.jpedsurg.2008.10.043","article-title":"Decreased mortality but increased morbidity in neonates with jejunoileal atresia; a study of 114 cases over a 34-year period","volume":"44","author":"Stollman","year":"2009","journal-title":"J Pediatr Surg"},{"issue":"1","key":"2023050103171040300_B10","first-page":"3","article-title":"Congenital jejuno-ileal atresia: observations on its pathogenesis and treatment","volume":"33","author":"Louw","year":"1981","journal-title":"Z Kinderchir"},{"issue":"5","key":"2023050103171040300_B11","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1001\/archsurg.133.5.490","article-title":"Intestinal atresia and stenosis: a 25-year experience with 277 cases","volume":"133","author":"Dalla Vecchia","year":"1998","journal-title":"Arch Surg"},{"key":"2023050103171040300_B12","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1159\/000484197","article-title":"Diagnosis and management of necrotizing enterocolitis: an international survey of neonatologists and pediatric surgeons","volume":"113","author":"Valpacos","year":"2018","journal-title":"Neonatology"},{"issue":"3","key":"2023050103171040300_B13","doi-asserted-by":"crossref","first-page":"337","DOI":"10.7863\/jum.2006.25.3.337","article-title":"Congenital jejunal and ileal atresia: natural prenatal sonographic history and association with neonatal outcome","volume":"25","author":"Wax","year":"2006","journal-title":"J Ultrasound Med"},{"issue":"5","key":"2023050103171040300_B14","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1002\/uog.14651","article-title":"Accuracy of prenatal ultrasound in detecting jejunal and ileal atresia: systematic review and meta-analysis","volume":"45","author":"Virgone","year":"2015","journal-title":"Ultrasound Obstet Gynecol"}],"container-title":["NeoReviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/neoreviews\/article-pdf\/24\/5\/e300\/1475111\/neoreviews.062020iositn00092.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/neoreviews\/article-pdf\/24\/5\/e300\/1475111\/neoreviews.062020iositn00092.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T03:17:28Z","timestamp":1682911048000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/neoreviews\/article\/24\/5\/e300\/191118\/Does-Preterm-Status-Hinder-the-Timely-Diagnosis-of"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,1]]},"references-count":14,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,5,1]]},"published-print":{"date-parts":[[2023,5,1]]}},"URL":"https:\/\/doi.org\/10.1542\/neo.24-5-e300","relation":{},"ISSN":["1526-9906"],"issn-type":[{"value":"1526-9906","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,1]]}}}