{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T01:23:26Z","timestamp":1769822606278,"version":"3.49.0"},"reference-count":29,"publisher":"American Academy of Pediatrics (AAP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,1]]},"abstract":"<jats:p>Perinatal substance use is rising in the United States, contributing to increasing numbers of infants with prenatal substance exposure and maternal mortality due to substance use disorder (SUD). Nearly every state in the United States has a Perinatal Quality Collaborative (PQC), and many focus on standardizing care, promoting evidence-based practices, and improving outcomes for pregnant people and infants affected by substance use. In this review, we summarize the strategies adopted by some PQCs including pregnancy and postpartum care bundles, universal SUD screening, mental health interventions, overdose prevention efforts, and management of neonatal opioid withdrawal syndrome. We describe positive outcomes of these initiatives, including decreased pharmacologic therapy and improved discharge practices. We also highlight some areas that require attention such as measuring short-term and long-term outcomes of these practices.<\/jats:p>","DOI":"10.1542\/neo.26-4-008","type":"journal-article","created":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T01:21:44Z","timestamp":1743470504000},"page":"e215-e222","source":"Crossref","is-referenced-by-count":1,"title":["State Initiatives to Improve Care for Infants With Prenatal Substance Exposure"],"prefix":"10.1542","volume":"26","author":[{"given":"Blair W.","family":"Weikel","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Section of Neonatology, University of Colorado School of Medicine, Aurora, Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunah S.","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Section of Neonatology, University of Colorado School of Medicine, Aurora, Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2025,4,1]]},"reference":[{"key":"2025040100032814000_r1","article-title":"2020 National survey on drug use and health: women","author":"Substance Abuse and Mental Health Services Administration","year":"2022"},{"key":"2025040100032814000_r2","article-title":"American Medical Association","author":"AMA report on overdose crisis in pregnant and postpartum people"},{"key":"2025040100032814000_r3","article-title":"Suicide, drug overdose top killers of new mothers in Colorado","author":"Melani"},{"issue":"suppl 1","key":"2025040100032814000_r4","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/s10995-023-03670-z","article-title":"Prenatal substance exposure and neonatal abstinence syndrome: state estimates from the 2016\u20132020 Transformed Medicaid Statistical Information System","volume":"27","author":"West","year":"2023","journal-title":"Matern Child Health 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Perinatal Quality Collaborative","author":"Results and past projects"},{"key":"2025040100032814000_r11","article-title":"Michigan Department of Health and Human Services","author":"Michigan Perinatal Quality Collaborative (MI PQC)"},{"key":"2025040100032814000_r12","author":"Colorado Maternal Mental Health Collaborative"},{"key":"2025040100032814000_r13","article-title":"CPCQC","author":"Improve Perinatal Access, Coordination, and Treatment for Behavioral Health (IMPACT BH)","year":"2024"},{"key":"2025040100032814000_r14","author":"Maternal Overdose Matters Plus (MOMs+)","year":"2024"},{"key":"2025040100032814000_r15","article-title":"Pennsylvania Perinatal Quality Collaborative","author":"Substance Use Disorder (SUD)\/Opioid Use Disorder (OUD)"},{"issue":"6","key":"2025040100032814000_r16","doi-asserted-by":"crossref","first-page":"e20163360","DOI":"10.1542\/peds.2016-3360","article-title":"An initiative to improve the quality of care of infants with neonatal abstinence 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