{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T01:00:42Z","timestamp":1780275642752,"version":"3.54.0"},"reference-count":71,"publisher":"American Academy of Pediatrics (AAP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,1]]},"abstract":"<jats:p>Sacrococcygeal teratoma (SCT) is the most common congenital germ cell tumor and is often detected antenatally. Advances in routine obstetric ultrasonography now allow for earlier risk stratification and identification of tumors that may precipitate potentially lethal conditions such as high-output cardiac failure, nonimmune hydrops, and maternal mirror syndrome. Antenatal risk assessment integrates tumor morphology, growth kinetics, and fetal cardiovascular status to determine the optimal management strategy for both the fetus and the pregnant patient. Surgical management relies on multidisciplinary perinatal planning and includes complete oncologic resection with coccygectomy. Incomplete resection, tumor spillage, failure to remove the coccyx, and immature\/malignant tumor elements are the primary drivers of recurrence. Survival is generally favorable for resectable tumors, but long-term surveillance is important in order to monitor for recurrence and bladder and\/or bowel dysfunction. Surveillance with serial clinical examination, alpha-fetoprotein monitoring, and cross-sectional imaging is effective in identifying early recurrence. This review synthesizes the epidemiology, pathogenesis, antenatal and postnatal management, outcomes, and postoperative surveillance for SCTs.<\/jats:p>","DOI":"10.1542\/neo.27-6-020","type":"journal-article","created":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:04:15Z","timestamp":1780272255000},"page":"e355-e368","source":"Crossref","is-referenced-by-count":0,"title":["Antenatal and Postnatal Management of Sacrococcygeal Teratoma"],"prefix":"10.1542","volume":"27","author":[{"given":"William G.","family":"Lee","sequence":"first","affiliation":[{"name":"Division of Pediatric Surgery, Cedars-Sinai Medical Center, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eveline H.","family":"Shue","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Cedars-Sinai Medical Center, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2026,6,1]]},"reference":[{"issue":"902","key":"2026053120041356400_r1","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1136\/pgmj.76.902.754","article-title":"Sacrococcygeal teratoma in the perinatal period","volume":"76","author":"Tuladhar","year":"2000","journal-title":"Postgrad Med J."},{"issue":"12","key":"2026053120041356400_r2","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1002\/pd.6457","article-title":"Prognostic accuracy of factors associated with poor outcome in prenatally diagnosed sacrococcygeal teratoma: a systematic review and meta-analysis","volume":"43","author":"van Heurn","year":"2023","journal-title":"Prenat Diagn."},{"issue":"5","key":"2026053120041356400_r3","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1002\/uog.29110","article-title":"Growth velocity of fetal sacrococcygeal teratoma as predictor of perinatal morbidity and mortality: multicenter study","volume":"64","author":"Vinit","year":"2024","journal-title":"Ultrasound Obstet Gynecol."},{"issue":"1","key":"2026053120041356400_r4","doi-asserted-by":"crossref","first-page":"e29994","DOI":"10.1002\/pbc.29994","article-title":"Sacrococcygeal teratoma: long-term outcomes. 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