{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T11:53:41Z","timestamp":1769342021486,"version":"3.49.0"},"reference-count":12,"publisher":"American Academy of Pediatrics (AAP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1999,1,1]]},"abstract":"<jats:p>We present a full-term newborn infant who suffered from immediate postpartum severe respiratory distress. The infant had an inspiratory stridor as a result of a swelling of the soft palate, extending from the roof of the nasopharynx. Transoral endotracheal intubation resulted in normal saturation levels. Histologic examination after an open biopsy showed mature neuroglial tissue. Radiology demonstrated the presence of a right parapharyngeal process obstructing the nasopharynx and oropharynx and extending to the right middle and posterior fossa, via the foramen ovale. After transoral debulking, the infant was extubated successfully. After an uneventful period of 5 months, the patient was readmitted at our hospital for treatment of meningitis. Subsequently, the inspiratory stridor recurred, and staged surgery was performed. First, a transcranial approach was used to remove a large intradural part of the process and close the defect at Meckel's cave. Two weeks later the retro- and parapharyngeal part of the process were removed transorally. Given the site of the defect of the skull base and the intradural location of the process, the diagnosis is a transalar sphenoidal encephalocele. This is a rare type of basal encephalocele, and has never been reported in an infant nor known to present with respiratory distress. The pathogenesis, clinical presentation, pathology, and therapeutic implications of basal encephaloceles are discussed.<\/jats:p>","DOI":"10.1542\/peds.103.1.e12","type":"journal-article","created":{"date-parts":[[2004,8,13]],"date-time":"2004-08-13T23:45:45Z","timestamp":1092440745000},"page":"e12-e12","source":"Crossref","is-referenced-by-count":21,"title":["Transalar Sphenoidal Encephalocele and Respiratory Distress in a Neonate: A Case Report"],"prefix":"10.1542","volume":"103","author":[{"given":"Emmanuel A.M.","family":"Mylanus","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henry A.M.","family":"Marres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose\u0301","family":"Vlietman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis A.A.","family":"Kolle\u0301e","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans Peter M.","family":"Freihofer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henk O.M.","family":"Thijssen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joost","family":"de Vries","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pieter","family":"Wesseling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[1999,1,1]]},"reference":[{"key":"2021121019344513700_B1","doi-asserted-by":"crossref","first-page":"353","DOI":"10.3109\/15513818609068861","article-title":"Nasal gliomas and related brain heterotopias: a pathologist's perspective.","volume":"5","author":"Patterson","year":"1986","journal-title":"Pediatr Pathol"},{"key":"2021121019344513700_B2","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0165-5876(87)90030-9","article-title":"Nasopharyngeal teratoma in the neonate.","volume":"14","author":"Cohen","year":"1987","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"2021121019344513700_B3","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1001\/archotol.1965.00760010529015","article-title":"Intranasal encephaloceles.","volume":"82","author":"Blumenfeld","year":"1965","journal-title":"Arch Otolaryngol"},{"key":"2021121019344513700_B4"},{"key":"2021121019344513700_B5","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1227\/00006123-198609000-00025","article-title":"Anterior basal encephalocele of the neonatal and infantile period.","volume":"19","author":"Yokota","year":"1986","journal-title":"Neurosurg."},{"key":"2021121019344513700_B6","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1177\/000348948509400522","article-title":"Transsphenoidal encephalocele.","volume":"94","author":"Kenna","year":"1985","journal-title":"Ann Otolaryngol Rhinol Laryngol"},{"key":"2021121019344513700_B7","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1148\/radiology.170.1.2909104","article-title":"Transalar sphenoidal encephaloceles: clinical and radiological findings.","volume":"170","author":"Elster","year":"1989","journal-title":"Radiology"},{"key":"2021121019344513700_B8","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0009-9260(05)80359-9","article-title":"Transalar sphenoidal encephalocele. Uncommon clinical and radiological findings.","volume":"43","author":"Soyer","year":"1991","journal-title":"Clin Radiol."},{"key":"2021121019344513700_B9","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1097\/00005537-199707000-00014","article-title":"Congenital encephalocele of the medial skull base.","volume":"107","author":"Mulcahy","year":"1997","journal-title":"Laryngoscope"},{"key":"2021121019344513700_B10","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3171\/jns.1970.32.2.0209","article-title":"The prognosis of encephaloceles.","volume":"32","author":"Mealey","year":"1970","journal-title":"J Neurosurg"},{"key":"2021121019344513700_B11","doi-asserted-by":"crossref","first-page":"531","DOI":"10.3109\/15513818909026912","article-title":"Nasal cerebral heterotopia: the so-called nasal glioma or sequestered encephalocele and its variants.","volume":"9","author":"Yeoh","year":"1989","journal-title":"Pediatr Pathol."},{"key":"2021121019344513700_B12","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1177\/000348948609500421","article-title":"Magnetic resonance imaging in encephaloceles.","volume":"95","author":"Lusk","year":"1896","journal-title":"Ann Otol Rhinol Laryngol"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/103\/1\/e12\/841345\/e12.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/103\/1\/e12\/841345\/e12.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,11]],"date-time":"2021-12-11T05:54:09Z","timestamp":1639202049000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/103\/1\/e12\/62104\/Transalar-Sphenoidal-Encephalocele-and-Respiratory"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,1,1]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[1999,1,1]]},"published-print":{"date-parts":[[1999,1,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.103.1.e12","relation":{},"ISSN":["1098-4275","0031-4005"],"issn-type":[{"value":"1098-4275","type":"electronic"},{"value":"0031-4005","type":"print"}],"subject":[],"published":{"date-parts":[[1999,1,1]]}}}