{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:27:15Z","timestamp":1770823635876,"version":"3.50.1"},"reference-count":8,"publisher":"American Academy of Pediatrics (AAP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1999,2,1]]},"abstract":"<jats:p>\u2003We describe the complex presentation of a patient with renal medullary carcinoma, a newly described entity primarily affecting young patients with sickle cell trait. Renal medullary carcinoma is an aggressive, rapidly destructive tumor associated with a delayed diagnosis and a poor outcome. The most common presenting signs and symptoms include hematuria, abdominal or flank pain, and weight loss. Sickle cell trait as the sole cause of hematuria in young black patients is a diagnosis of exclusion. Hemoglobin electrophoresis, intravenous pyelography, and computed tomography scans should be the minimal studies performed in young black patients with hematuria.<\/jats:p>","DOI":"10.1542\/peds.103.2.e22","type":"journal-article","created":{"date-parts":[[2004,8,13]],"date-time":"2004-08-13T23:45:45Z","timestamp":1092440745000},"page":"e22-e22","source":"Crossref","is-referenced-by-count":28,"title":["Renal Medullary Carcinoma in an Adolescent With Sickle Cell Trait"],"prefix":"10.1542","volume":"103","author":[{"given":"Katherine E.","family":"Warren","sequence":"first","affiliation":[{"name":"From the National Cancer Institute, and National Naval Medical Center, Department of Pediatrics, Bethesda, Maryland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vinod","family":"Gidvani-Diaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bertrand","family":"Duval-Arnould","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[1999,2,1]]},"reference":[{"key":"2021121000342808100_B1","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/S0022-3476(75)80484-7","article-title":"Incidence of malignant tumors in US children.","volume":"86","author":"Young","year":"1975","journal-title":"J Pediatr."},{"key":"2021121000342808100_B2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00000478-199501000-00001","article-title":"Renal medullary carcinoma: the seventh sickle cell nephropathy.","volume":"19","author":"Davis","year":"1995","journal-title":"Am J Surg Pathol."},{"key":"2021121000342808100_B3","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/BF00858138","article-title":"Renal cell carcinoma developing in the pediatric recipient of an adult cadaveric donor kidney.","volume":"8","author":"Agrawal","year":"1994","journal-title":"Pediatr Nephrol."},{"key":"2021121000342808100_B4","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1148\/radiology.195.1.7892499","article-title":"Renal medullary carcinoma associated with sickle cell trait: radiologic findings.","volume":"195","author":"Davidson","year":"1995","journal-title":"Radiology."},{"key":"2021121000342808100_B5","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1001\/jama.1974.03230350051035","article-title":"Sickle cell nephropathy.","volume":"228","author":"Berman","year":"1974","journal-title":"JAMA."},{"key":"2021121000342808100_B6","first-page":"133","article-title":"Sickle cell nephropathy.","volume":"23","author":"Falk","year":"1994","journal-title":"Adv Nephrol."},{"key":"2021121000342808100_B7","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/(SICI)1097-0142(19960701)78:1<128::AID-CNCR18>3.0.CO;2-1","article-title":"Renal medullary carcinoma. Clinical and therapeutic aspects of a newly described tumor.","volume":"78","author":"Avery","year":"1996","journal-title":"Cancer."},{"key":"2021121000342808100_B8","first-page":"783","article-title":"Renal cell carcinoma in a child with hemoglobin SA disease.","volume":"142","author":"Kawanami","year":"1988","journal-title":"Am J Dis Child."}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/103\/2\/e22\/887709\/pe029900022o.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/103\/2\/e22\/887709\/pe029900022o.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,10]],"date-time":"2021-12-10T07:26:54Z","timestamp":1639121214000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/103\/2\/e22\/62137\/Renal-Medullary-Carcinoma-in-an-Adolescent-With"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,2,1]]},"references-count":8,"journal-issue":{"issue":"2","published-online":{"date-parts":[[1999,2,1]]},"published-print":{"date-parts":[[1999,2,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.103.2.e22","relation":{},"ISSN":["1098-4275","0031-4005"],"issn-type":[{"value":"1098-4275","type":"electronic"},{"value":"0031-4005","type":"print"}],"subject":[],"published":{"date-parts":[[1999,2,1]]}}}