{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T23:25:03Z","timestamp":1781133903868,"version":"3.54.1"},"reference-count":12,"publisher":"American Academy of Pediatrics (AAP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1999,11,1]]},"abstract":"<jats:sec>\n                  <jats:title>Objective.<\/jats:title>\n                  <jats:p>This study was an assessment of potential exposures of medical personnel to nitrogen oxides during simulated and actual inhaled nitric oxide treatment of newborn and pediatric patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Design.<\/jats:title>\n                  <jats:p>Breathing zone exposures to nitric oxide (NO) and nitrogen dioxide (NO2) were monitored using data-logging personal dosimeters during simulated and actual administration of NO gas to patients in an intensive care setting.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Sample.<\/jats:title>\n                  <jats:p>A total of 28 bedside nurses and 18 respiratory therapists were monitored during 6 different patient treatments.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Analysis.<\/jats:title>\n                  <jats:p>The highest measured concentrations of NO and NO2 in the personal breathing zones of the nurses and respiratory therapists were peak readings (&amp;lt;1 minute in duration) of 6.7 parts per million (ppm) NO and 3.1 ppm NO2. Exposures averaged throughout 15 minutes and throughout the work shift were below the limit of detection (0.8-ppm NO and 0.5-ppm NO2).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion.<\/jats:title>\n                  <jats:p>Detectable exposures to NO and NO2were brief, infrequent, and well below Occupational Safety and Health Administration permissible exposure limits or any other exposure guideline, eg, American Conference of Governmental Hygienists Threshold Limit Values.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1542\/peds.104.5.1095","type":"journal-article","created":{"date-parts":[[2004,8,13]],"date-time":"2004-08-13T23:45:45Z","timestamp":1092440745000},"page":"1095-1100","source":"Crossref","is-referenced-by-count":21,"title":["Assessment of Medical Personnel Exposure to Nitrogen Oxides During Inhaled Nitric Oxide Treatment of Neonatal and Pediatric Patients"],"prefix":"10.1542","volume":"104","author":[{"given":"Margaret L.","family":"Phillips","sequence":"first","affiliation":[{"name":"From the Department of Occupational and Environmental Health, College of Public Health, University of Oklahoma Health Sciences Center; and the"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas A.","family":"Hall","sequence":"additional","affiliation":[{"name":"From the Department of Occupational and Environmental Health, College of Public Health, University of Oklahoma Health Sciences Center; and the"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishnamurthy","family":"Sekar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children's Hospital of Oklahoma, Oklahoma City, Oklahoma."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanine L.","family":"Tomey","sequence":"additional","affiliation":[{"name":"From the Department of Occupational and Environmental Health, College of Public Health, University of Oklahoma Health Sciences Center; and the"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[1999,11,1]]},"reference":[{"key":"2021121003051051700_B1","first-page":"83","article-title":"Nitric oxide.","volume":"14","author":"Holowaty","year":"1995","journal-title":"Neonatal Network."},{"key":"2021121003051051700_B2","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1542\/peds.101.3.325","article-title":"Inhaled nitric oxide for the early treatment of persistent pulmonary hypertension of the term newborn: a randomized, double-masked, placebo-controlled, dose-response, multicenter study.","volume":"101","author":"Davidson","year":"1998","journal-title":"Pediatrics."},{"key":"2021121003051051700_B3","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1093\/bja\/39.5.405","article-title":"The chemistry of the in-vivo reaction between haemoglobin and various oxides of nitrogen.","volume":"39","author":"Toothill","year":"1967","journal-title":"Br J Anaesth."},{"key":"2021121003051051700_B4","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/BF01728336","article-title":"Delivery and monitoring of inhaled nitric oxide.","volume":"22","author":"Young","year":"1996","journal-title":"Intensive Care Med."},{"key":"2021121003051051700_B5","first-page":"81","article-title":"Composition of nitrous fumes from industrial processes.","volume":"1","author":"Wade","year":"1950","journal-title":"Arch Industrial Hygiene and Occupational Med."},{"key":"2021121003051051700_B6","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1016\/0140-6736(92)91886-D","article-title":"Safety guidelines for use of nitric oxide.","volume":"339","author":"Foubert","year":"1992","journal-title":"Lancet."},{"key":"2021121003051051700_B7","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/0140-6736(93)91267-P","article-title":"Safety requirement for use of inhaled nitric oxide in neonates.","volume":"341","author":"Bouchet","year":"1993","journal-title":"Lancet."},{"key":"2021121003051051700_B8"},{"key":"2021121003051051700_B9"},{"key":"2021121003051051700_B10"},{"key":"2021121003051051700_B11"},{"key":"2021121003051051700_B12"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/104\/5\/1095\/840271\/1095.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/104\/5\/1095\/840271\/1095.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,10]],"date-time":"2021-12-10T09:35:27Z","timestamp":1639128927000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/104\/5\/1095\/62600\/Assessment-of-Medical-Personnel-Exposure-to"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,11,1]]},"references-count":12,"journal-issue":{"issue":"5","published-online":{"date-parts":[[1999,11,1]]},"published-print":{"date-parts":[[1999,11,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.104.5.1095","relation":{},"ISSN":["1098-4275","0031-4005"],"issn-type":[{"value":"1098-4275","type":"electronic"},{"value":"0031-4005","type":"print"}],"subject":[],"published":{"date-parts":[[1999,11,1]]}}}