{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:15:42Z","timestamp":1787238942439,"version":"build-2736575974"},"reference-count":22,"publisher":"American Academy of Pediatrics (AAP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,2,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective.<\/jats:title>\n                    <jats:p>To determine whether routine follow-up coagulation studies are useful in children with accidental exposures to rodenticides containing superwarfarin compounds.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design.<\/jats:title>\n                    <jats:p>Retrospective review of poison center charts involving pediatric superwarfarin exposures occurring in two 2-year periods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting.<\/jats:title>\n                    <jats:p>An American Association of Poison Control Centers-certified regional poison control center with an annual call volume of 55\u2009000 calls per year from a 2-state area with a combined population of 4 million people.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcome Measures.<\/jats:title>\n                    <jats:p>Prothrombin times and\/or international normalized ratios and reported clinical signs of excessive anticoagulation after exposure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results.<\/jats:title>\n                    <jats:p>Of 542 children in 4 years of data collection, follow-up prothrombin times and\/or international normalized ratios measurements did not detect any significant coagulation abnormalities. No child developed bleeding complications. No child required or received antidotal treatment with vitamin K.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion.<\/jats:title>\n                    <jats:p>Normal preschool-aged children with unintentional acute exposures to superwarfarin rodenticides do not require any routine follow-up laboratory studies and do not require any medical intervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1542\/peds.105.2.402","type":"journal-article","created":{"date-parts":[[2004,8,13]],"date-time":"2004-08-13T19:50:41Z","timestamp":1092426641000},"page":"402-404","source":"Crossref","is-referenced-by-count":32,"title":["Unintentional Pediatric Superwarfarin Exposures: Do We Really Need a Prothrombin Time?"],"prefix":"10.1542","volume":"105","author":[{"given":"Michael E.","family":"Mullins","sequence":"first","affiliation":[{"name":"1From the Oregon Poison Center, Department of Emergency Medicine, Oregon Health 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