{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T20:58:12Z","timestamp":1769633892436,"version":"3.49.0"},"reference-count":23,"publisher":"American Academy of Pediatrics (AAP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,10,1]]},"abstract":"\n Objective.<\/jats:title>\n Because of questions about the basis for the use of naloxone in resuscitation of the newborn, we wished to evaluate the use of naloxone at our institution and an affiliated hospital.<\/jats:p>\n <\/jats:sec>\n \n Methodology.<\/jats:title>\n Evaluation of the actual use of naloxone at a university hospital and a community hospital: we document naloxone use by daily survey for a month in one; in the other, we perform a retrospective record review of 1 year's use.<\/jats:p>\n <\/jats:sec>\n \n Results.<\/jats:title>\n The university hospital had 240 births during February, 1998. Naloxone was given twice: once, 7 minutes before delivery to a woman at term who had received opiates about 2 hours previously; and once, intramuscularly, to a premature infant for apnea, before being intubated. The community hospital had 2044 births during fiscal 1998. Twenty-six neonates were identified as having received naloxone. Of the 26, 13 received naloxone without needing ventilatory support; all 13 with respiratory depression had a predisposing perinatal complication.<\/jats:p>\n <\/jats:sec>\n \n Conclusion.<\/jats:title>\n The use of naloxone in practice may not conform to the American Academy of Pediatrics' guidelines for use in resuscitation of the newborn. The use of naloxone in resuscitation of the newborn should be reevaluated.<\/jats:p>\n <\/jats:sec>","DOI":"10.1542\/peds.106.4.831","type":"journal-article","created":{"date-parts":[[2004,8,13]],"date-time":"2004-08-13T23:50:41Z","timestamp":1092441041000},"page":"831-834","source":"Crossref","is-referenced-by-count":19,"title":["Role of Naloxone in Newborn Resuscitation"],"prefix":"10.1542","volume":"106","author":[{"given":"Marguerite","family":"Herschel","sequence":"first","affiliation":[{"name":"Department of Pediatrics"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Babak","family":"Khoshnood","sequence":"additional","affiliation":[{"name":"Department of Pediatrics"},{"name":"University of Chicago Pritzker School of Medicine and the Irving B. Harris Graduate School of Public Policy Studies"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy A.","family":"Lass","sequence":"additional","affiliation":[{"name":"Committee on Clinical Pharmacology"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2000,10,1]]},"reference":[{"key":"2021121009271763500_B1","first-page":"305","article-title":"Use of naloxone at Norwegian maternity centres.","volume":"114","author":"Fagerli","year":"1994","journal-title":"Tidsskr Nor Laegeforen."},{"key":"2021121009271763500_B2","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1542\/peds.65.3.667","article-title":"Naloxone use in newborns.","volume":"65","author":"American Academy of Pediatrics, Committee on Drugs","year":"1980","journal-title":"Pediatrics."},{"key":"2021121009271763500_B3"},{"key":"2021121009271763500_B4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0095-5108(18)30132-5","article-title":"Controversies in neonatal resuscitation.","volume":"25","author":"Ginsberg","year":"1998","journal-title":"Clin Perinatol."},{"key":"2021121009271763500_B5","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1016\/0002-9378(52)90212-3","article-title":"The transmission of meperidine across the human placenta.","volume":"64","author":"Apgar","year":"1952","journal-title":"Am J Obstet Gynecol."},{"key":"2021121009271763500_B6","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/S0022-3476(77)80574-X","article-title":"Respiratory depression at birth\u2014value of Apgar score and ventilatory measurements in its detection.","volume":"90","author":"Gerhardt","year":"1977","journal-title":"J Pediatr."},{"key":"2021121009271763500_B7","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/S0022-3476(79)80369-8","article-title":"Naloxone reversal of mild neurobehavioral depression in normal newborns after routine obstetric analgesia.","volume":"94","author":"Bonta","year":"1979","journal-title":"J Pediatr."},{"key":"2021121009271763500_B8","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1203\/00006450-199210000-00009","article-title":"Neonatal pattern of breathing during active and quiet sleep after maternal administration of meperidine.","volume":"32","author":"Hamza","year":"1992","journal-title":"Pediatr Res."},{"key":"2021121009271763500_B9","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/j.1651-2227.1997.tb08869.x","article-title":"Effects of routinely given pethidine during labour on infants' developing breastfeeding behavior. 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