{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T19:19:57Z","timestamp":1792523997548,"version":"4.5.0"},"reference-count":38,"publisher":"American Academy of Pediatrics (AAP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2001,4,1]]},"abstract":"<jats:sec><jats:title>Objective.<\/jats:title><jats:p>To compare findings on hard copies of cranial ultrasound (US) and magnetic resonance imaging (MRI) obtained between birth and term in a group of preterm infants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants and Methods.<\/jats:title><jats:p>Infants born at or below a gestational age of 30 weeks who underwent cranial US scan and MRI on the same day were eligible for this study. Infants underwent, whenever possible, 3 scans between birth and term. We calculated the predictive probability (PP) of US findings as a predictor of findings on MRI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>Sixty-two paired MRI and US studies were performed between birth and term in 32 infants born at a median gestational age of 27 (range: 23\u201330) weeks and a median birth weight of 918 (530\u20131710) grams. US predicted some MRI findings accurately: germinal layer hemorrhage (GLH) on US had a PP of 0.8 with a 95% confidence interval of (0.70\u20130.90) for the presence of GLH on MRI, intraventricular hemorrhage (IVH) on US had a PP of 0.85 (0.76\u20130.94) for the presence of IVH on MRI, and severe white matter (WM) echogenicity on US had a PP of 0.96 (0.92\u20131.0) for the presence of WM hemorrhagic parenchymal infarction on MRI. Other MRI changes were less well-predicted: mild or no WM echogenicity on US had a PP of 0.54 (0.41\u20130.66) for the presence of normal WM signal intensity on MRI, and moderate or severe WM echogenicity on US had a PP of 0.54 (0.42\u20130.66) for the presence of small petechial WM hemorrhage and\/or diffuse excessive high-signal intensity (DEHSI) in the WM on T2-weighted images on MRI. However, mild\/moderate or severe WM echogenicity on US scans performed at \u22657 days after birth had a PP of 0.72 (0.58\u20130.87) for the presence of WM hemorrhage and\/or DEHSI on MRI. There were no cases of cystic periventricular leukomalacia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>US accurately predicted the presence of GLH, IVH, and hemorrhagic parenchymal infarction on MRI. However, its ability to predict the presence of DEHSI and small petechial hemorrhages in the WM on T2 weighted images is not as good, but improves on scans performed at \u22657 days after birth. In addition, normal WM echogenicity on US is not a good predictor of normal WM signal intensity on MRI.<\/jats:p><\/jats:sec>","DOI":"10.1542\/peds.107.4.719","type":"journal-article","created":{"date-parts":[[2004,8,13]],"date-time":"2004-08-13T23:55:51Z","timestamp":1092441351000},"page":"719-727","source":"Crossref","is-referenced-by-count":315,"title":["Comparison of Findings on Cranial Ultrasound and Magnetic Resonance Imaging in Preterm Infants"],"prefix":"10.1542","volume":"107","author":[{"given":"Elia F.","family":"Maalouf","sequence":"first","affiliation":[{"name":"From the Department of Paediatrics, Imperial College School of Medicine and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip J.","family":"Duggan","sequence":"additional","affiliation":[{"name":"From the Department of Paediatrics, Imperial College School of Medicine and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serena J.","family":"Counsell","sequence":"additional","affiliation":[{"name":"Robert Steiner MR Unit, Medical Research Council Clinical Sciences Centre, Hammersmith Hospital, London, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary A.","family":"Rutherford","sequence":"additional","affiliation":[{"name":"Robert Steiner MR Unit, Medical Research Council Clinical Sciences Centre, Hammersmith Hospital, London, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frances","family":"Cowan","sequence":"additional","affiliation":[{"name":"From the Department of Paediatrics, Imperial College School of Medicine and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Azzopardi","sequence":"additional","affiliation":[{"name":"From the Department of Paediatrics, Imperial College School of Medicine and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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