{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T08:50:35Z","timestamp":1760863835433,"version":"3.40.5"},"reference-count":19,"publisher":"American Academy of Pediatrics (AAP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2002,6,1]]},"abstract":"<jats:p>Objective. The purpose of this study was to determine the prevalence of kyphosis in a Turner syndrome (TS) population.<\/jats:p>\n               <jats:p>Methods. Standing lateral thoracic spine and standing anterior-posterior (A-P) scoliosis radiographs were obtained on all girls with TS between the ages of 5 and 18 years seen in a TS clinic between July 2000 and March 2001. Medical histories were reviewed, and a pediatric orthopedic surgeon evaluated the radiographs of each patient (N = 25). Excessive kyphosis was defined as an A-P curvature &amp;gt;40\u00b0, vertebral wedging as any A-P deformity &amp;gt;5\u00b0 at an individual vertebral body, and scoliosis as a lateral curvature &amp;gt;10\u00b0.<\/jats:p>\n               <jats:p>Results. Fifteen (60%) of 25 patients were found to have abnormal radiographic findings: 10 (40%) of 25 with excessive kyphosis, 10 (40%) of 25 with vertebral wedging, and 5 (20%) of 25 with scoliosis. Forty-eight percent of the girls had both excessive kyphosis and\/or vertebral body wedging. Two girls had kyphosis \u226555\u00b0, and 5 had scoliosis \u226525\u00b0. Girls with excessive kyphosis and\/or vertebral body wedging were older (13.6 \u00b1 3.9 years vs 10.6 \u00b1 2.8 years).<\/jats:p>\n               <jats:p>Conclusions. The prevalence of excessive kyphosis and vertebral body wedging seems to be increased in girls with TS and corresponds with advancing age. Routine radiologic surveillance may facilitate detection of developing deformities so that treatment with a brace can be considered to prevent or slow the process.<\/jats:p>","DOI":"10.1542\/peds.109.6.e93","type":"journal-article","created":{"date-parts":[[2004,8,14]],"date-time":"2004-08-14T00:17:55Z","timestamp":1092442675000},"page":"e93-e93","source":"Crossref","is-referenced-by-count":27,"title":["Kyphosis in a Turner Syndrome Population"],"prefix":"10.1542","volume":"109","author":[{"given":"Deborah A.","family":"Elder","sequence":"first","affiliation":[{"name":"Division of Endocrinology, Children\u2019s Hospital Medical Center, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary Gwyn","family":"Roper","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard C.","family":"Henderson","sequence":"additional","affiliation":[{"name":"Orthopaedics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marsha L.","family":"Davenport","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2002,6,1]]},"reference":[{"key":"2021121006245396200_R1","unstructured":"Lippe BM. Turner syndrome. In: Sperling MA, ed. Pediatric Endocrinology. Philadelphia, PA: WB Saunders Co; 1996:387\u2013421"},{"key":"2021121006245396200_R2","doi-asserted-by":"crossref","unstructured":"Saenger P. Turner\u2019s syndrome. N Engl J Med.1996;335:1749\u20131754","DOI":"10.1056\/NEJM199612053352307"},{"key":"2021121006245396200_R3","doi-asserted-by":"crossref","unstructured":"Muller G, Gschwend N. Endocrine disorders and Scheuermann\u2019s disease. Arch Orthop Unfallchir.1969;65:357\u2013362","DOI":"10.1007\/BF00417219"},{"key":"2021121006245396200_R4","doi-asserted-by":"crossref","unstructured":"al Attas RA, Rahi AH, Ahmed E. Common variable immunodeficiency with CD4+ T lymphocytopenia and overproduction of soluble IL-2 receptor associated with Turner\u2019s syndrome and dorsal kyphoscoliosis. J Clin Pathol.1997;50:876\u2013879","DOI":"10.1136\/jcp.50.10.876"},{"key":"2021121006245396200_R5","unstructured":"Kosowicz J. Skeletal changes in Turner\u2019s syndrome and their significance in differential diagnosis. Polish Med Hist Sc Bull.1959;2:23\u201326"},{"key":"2021121006245396200_R6","doi-asserted-by":"crossref","unstructured":"Preger L, Steinbach HL, Moskowitz P, Scully AL, Goldberg MB. Roentgenographic abnormalitites in phenotypic females with gonadal dysgenesis. AJR Am J Roentgenol.1968;104:899\u2013910","DOI":"10.2214\/ajr.104.4.899"},{"key":"2021121006245396200_R7","doi-asserted-by":"crossref","unstructured":"Beals RK. Orthopedic aspects of the XO (Turner\u2019s) syndrome. Clin Orthop.1973;97:19\u201330","DOI":"10.1097\/00003086-197311000-00004"},{"key":"2021121006245396200_R8","unstructured":"Lubin MB, Gruber HD, Rimoin DL, Lachman RS. Skeletal abnormalities in Turner syndrome. In: Rosenfeld RG, Grumbach MM, eds. Turner Syndrome. New York, NY: Marcel Dekker Inc;1990:281\u2013300"},{"key":"2021121006245396200_R9","unstructured":"Ascani E, Salsano V, Giglio G. The incidence and early detection of spinal deformities. A study based on the screening of 16,104 schoolchildren. Ital J Orthop Traumatol.1977;3:111\u2013117"},{"key":"2021121006245396200_R10","doi-asserted-by":"crossref","unstructured":"Wenger DR, Frick SL. Scheuermann kyphosis. Spine.1999;24:2630\u20132639","DOI":"10.1097\/00007632-199912150-00010"},{"key":"2021121006245396200_R11","doi-asserted-by":"crossref","unstructured":"Nissinen M. Spinal posture during pubertal growth. Acta Paediatr.1995;84:308\u2013312","DOI":"10.1111\/j.1651-2227.1995.tb13634.x"},{"key":"2021121006245396200_R12","doi-asserted-by":"crossref","unstructured":"Gravholt CH, Juul S, Naeraa RW, Hansen J. Morbidity in Turner syndrome. J Clin Epidemiol.1998;51:147\u2013158","DOI":"10.1016\/S0895-4356(97)00237-0"},{"key":"2021121006245396200_R13","doi-asserted-by":"crossref","unstructured":"Blaschke RJ, Rappold GA. SHOX: Growth, Leri-Weill and Turner syndromes. Trends Endocrinol Metab.2000;11:227\u2013230","DOI":"10.1016\/S1043-2760(00)00262-9"},{"key":"2021121006245396200_R14","doi-asserted-by":"crossref","unstructured":"Clement-Jones M, Schiller S, Rao E, et al. The short stature homeobox gene SHOX is involved in skeletal abnormalities in Turner syndrome. Hum Mol Genet.2000;9:695\u2013702","DOI":"10.1093\/hmg\/9.5.695"},{"key":"2021121006245396200_R15","doi-asserted-by":"crossref","unstructured":"Gravholt CH, Naeraa RW. Reference values for body proportions and body composition in adult women with Ullrich-Turner syndrome. Am J Med Genet.1997;72:403\u2013408","DOI":"10.1002\/(SICI)1096-8628(19971112)72:4<403::AID-AJMG6>3.0.CO;2-R"},{"key":"2021121006245396200_R16","doi-asserted-by":"crossref","unstructured":"Even L, Bronstein V, Hochberg Z. Bone maturation in girls with Turner\u2019s syndrome. Eur J Endocrinol.1998;138:59\u201362","DOI":"10.1530\/eje.0.1380059"},{"key":"2021121006245396200_R17","doi-asserted-by":"crossref","unstructured":"Rubin K. Turner syndrome and osteoporosis: mechanisms and prognosis. Pediatrics.1998;102(suppl):481\u2013485","DOI":"10.1542\/peds.102.S3.481"},{"key":"2021121006245396200_R18","doi-asserted-by":"crossref","unstructured":"Sato N, Nimura A, Horikawa R, Katumata N, Tanae A, Tanaka T. Bone mineral density in Turner syndrome: relation to GH treatment and estrogen treatment. Endocrinol J.2000;47(suppl):S115\u2013S119","DOI":"10.1507\/endocrj.47.SupplMarch_S115"},{"key":"2021121006245396200_R19","unstructured":"Freeman BLI. Scoliosis and kyphosis. In: Canale ST, ed. Campbell\u2019s Operative Orthopaedics. St Louis, MO: Mosby Inc; 1998:2941\u20132947"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/109\/6\/e93\/995966\/pe0602000e93.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/109\/6\/e93\/995966\/pe0602000e93.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,10]],"date-time":"2021-12-10T14:42:25Z","timestamp":1639147345000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/109\/6\/e93\/64186\/Kyphosis-in-a-Turner-Syndrome-Population"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,6,1]]},"references-count":19,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2002,6,1]]},"published-print":{"date-parts":[[2002,6,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.109.6.e93","relation":{},"ISSN":["0031-4005","1098-4275"],"issn-type":[{"type":"print","value":"0031-4005"},{"type":"electronic","value":"1098-4275"}],"subject":[],"published":{"date-parts":[[2002,6,1]]}}}