{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T01:56:14Z","timestamp":1767923774593,"version":"3.49.0"},"reference-count":12,"publisher":"American Academy of Pediatrics (AAP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,1,1]]},"abstract":"<jats:p>Background. Combination antifungal\/corticosteroid preparations are widely used by nondermatologists in the treatment of superficial fungal infections in patients of all ages. Over half of the prescriptions written for the most commonly used combination agent clotrimazole 1%\/betamethasone diproprionate 0.05% cream (Lotrisone, Schering, Kenilworth, NJ) were prescribed for children younger than 4 years old. Our pediatric dermatology division has recently encountered a series of children with recurrent or persistent tinea corporis, especially tinea faciei, treated initially with combination antifungal\/corticosteroid cream.<\/jats:p>\n               <jats:p>Methods. All children evaluated for tinea corporis in a university hospital pediatric dermatology clinic from January through June 2001 were identified from the clinic registry for a retrospective chart review. Response to therapy was confirmed by telephone survey and\/or follow-up visits at least 1 month after clearing of infection.<\/jats:p>\n               <jats:p>Results. Six children ranging in age from 4 to 11 years were evaluated for tinea corporis in a pediatric dermatology clinic at our institution during the 6-month period. All 6 children were diagnosed clinically by their pediatrician with tinea corporis and initially treated with clotrimazole 1%\/betamethasone diproprionate 0.05% cream for 2 to 12 months. In our pediatric dermatology clinic, patients had their diagnosis confirmed with a positive potassium hydroxide preparation and were treated with one of several oral or topical antifungal agents with clearing of all tinea infections.<\/jats:p>\n               <jats:p>Conclusion. The use of combination clotrimazole 1% cream\/betamethasone diproprionate 0.05% cream (Lotrisone) for the treatment of tinea corporis may be associated with persistent\/recurrent infection.<\/jats:p>","DOI":"10.1542\/peds.111.1.201","type":"journal-article","created":{"date-parts":[[2004,8,14]],"date-time":"2004-08-14T00:43:47Z","timestamp":1092444227000},"page":"201-203","source":"Crossref","is-referenced-by-count":52,"title":["Persistent and Recurrent Tinea Corporis in Children Treated With Combination Antifungal\/ Corticosteroid Agents"],"prefix":"10.1542","volume":"111","author":[{"given":"Sharonda J.","family":"Alston","sequence":"first","affiliation":[{"name":"Johns Hopkins University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard A.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Johns Hopkins University School of Medicine"},{"name":"Division of Pediatric Dermatology, Baltimore, MD 21287"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marisa","family":"Braun","sequence":"additional","affiliation":[{"name":"University of Maryland School of Medicine Baltimore, MD 21201"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2003,1,1]]},"reference":[{"key":"2021120821094486900_R1","doi-asserted-by":"crossref","unstructured":"Fleischer AB, Feldman SR. Prescription of high-potency corticosteroid agents and clotrimazole-betamethasone diproprionate by pediatricians. Clin Ther.1999;21:1725\u20131731","DOI":"10.1016\/S0149-2918(99)80051-4"},{"key":"2021120821094486900_R2","doi-asserted-by":"crossref","unstructured":"Smith EB, Fleischer AB, Feldman SR. Non-dermatologists are more likely than dermatologists to prescribe antifungal\/corticosteroid products: analysis of office visits for cutaneous fungal infections, 1990\u20131994. J Am Acad Dermatol.1998;39:43\u201347","DOI":"10.1016\/S0190-9622(98)70400-1"},{"key":"2021120821094486900_R3","unstructured":"Wortzel MH. A double-blind study comparing the superiority of a combination antifungal (clotrimazole)\/steroid (betamethasone diproprionate) product. Cutis.1982;30:258\u2013261"},{"key":"2021120821094486900_R4","doi-asserted-by":"crossref","unstructured":"Smith EB, Breneman DI, Griffith RF, et al. Double-blind comparison of naftifine cream and clotrimazole\/betamethasone diproprionate cream in the treatment of tinea pedis. J Am Acad Dermatol.1992;26:125\u2013127","DOI":"10.1016\/S0190-9622(08)80528-2"},{"key":"2021120821094486900_R5","doi-asserted-by":"crossref","unstructured":"Nada M, Hanafi S, Al-Omari H, et al. Naftifine versus miconazole\/hydrocortisone in inflammatory dermatophyte infections. Int J Dermatol.1994;33:570\u2013572","DOI":"10.1111\/j.1365-4362.1994.tb02899.x"},{"key":"2021120821094486900_R6","doi-asserted-by":"crossref","unstructured":"Evans EG, James IGV, Seaman RAJ, Richardson MD. Does naftifine have anti-inflammatory properties? A double blind study with 1% clotrimazole\/1% hydrocortisone in clinically diagnosed fungal infection of the skin. J Am Acad Dermatol.1993;129:437\u2013442","DOI":"10.1111\/j.1365-2133.1993.tb03172.x"},{"key":"2021120821094486900_R7","unstructured":"Katz HI, Bard JB, Cole GW, et al. SCH 370 (clotrimazole-betamethasone diproprionate cream) in patients with tinea curis or tinea corporis. Cutis.1984;34:183\u2013187"},{"key":"2021120821094486900_R8","unstructured":"Elewski BE, Jones T, Zaias N. Comparison of an antifungal used alone with an antifungal used with a topical steroid in inflammatory tinea pedis. Cutis.1996;58:305\u2013307"},{"key":"2021120821094486900_R9","doi-asserted-by":"crossref","unstructured":"Drake LA, Dinehart SM, Farmer ER, et al. Guidelines of care for superficial mycotic infections of the skin: tinea corporis, tinea curis, tinea faciei, tinea manuum, and tinea pedis. J Am Acad Dermatol.1996;34:282\u2013286","DOI":"10.1016\/S0190-9622(96)80135-6"},{"key":"2021120821094486900_R10","doi-asserted-by":"crossref","unstructured":"Barkey WF. Striae and persistent tinea corporis related to prolonged use of betamethasone diproprionate 0.005% cream\/clotrimazole 1% cream (Lotrisone cream). J Am Acad Dermatol.1987;17:518\u2013519","DOI":"10.1016\/S0190-9622(87)80380-8"},{"key":"2021120821094486900_R11","doi-asserted-by":"crossref","unstructured":"Rosen T, Elewski BE. Failure of clotrimazole-betamethasone diproprionate cream in the treatment of Microsporum canis infections. J Am Acad Dermatol.1995;32:1050\u20131052","DOI":"10.1016\/0190-9622(95)91360-2"},{"key":"2021120821094486900_R12","doi-asserted-by":"crossref","unstructured":"Reynolds RD, Boiko S, Lucky AW. Exacerbation of tinea corporis during treatment with 1% clotrimazole\/betamethasone diproprionate (Lotrisone) [letter]. Am J Dis Child.1991;145:1224\u20131225","DOI":"10.1001\/archpedi.1991.02160110014007"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/111\/1\/201\/1006309\/pe0103000201.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/111\/1\/201\/1006309\/pe0103000201.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T01:09:28Z","timestamp":1639012168000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/111\/1\/201\/28523\/Persistent-and-Recurrent-Tinea-Corporis-in"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1,1]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2003,1,1]]},"published-print":{"date-parts":[[2003,1,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.111.1.201","relation":{},"ISSN":["0031-4005","1098-4275"],"issn-type":[{"value":"0031-4005","type":"print"},{"value":"1098-4275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,1,1]]}}}