{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T20:14:58Z","timestamp":1774124098207,"version":"3.50.1"},"reference-count":19,"publisher":"American Academy of Pediatrics (AAP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,9,1]]},"abstract":"<jats:p>Objective. To determine whether active smoking has an adverse impact on respiratory function of young adults of extremely low birth weight (ELBW; birth weight &amp;lt;1000 g).<\/jats:p><jats:p>Methods. This was a cohort study of 60 consecutive ELBW survivors who were born during 1977\u20131980 at Royal Women\u2019s Hospital, Melbourne, Australia. Respiratory function was measured on 44 (73%) of the subjects at a mean age of 20.2 years (standard deviation: 1.0 year). Respiratory function had also been measured on 42 of the 44 subjects at 8 years of age. Respiratory function was compared between the 14 smokers and the 30 nonsmokers.<\/jats:p><jats:p>Results. Several respiratory function variables reflecting airflow (the forced expired volume in 1 second [FEV1]\/forced vital capacity [FVC] ratio; flow rates at 75%, 50%, and 25% of vital capacity; and mid-expiratory flow from 25% to 75% of vital capacity) were significantly diminished in smokers. The proportion with a clinically important reduction in the FEV1\/FVC ratio (&amp;lt;75%) was significantly higher in smokers (64%) than in nonsmokers (20%). There was a significantly larger decrease in the FEV1\/FVC ratio between ages 8 and 20 years in the smokers (mean change: \u22128.2%; 95% confidence interval: \u221214.1% to \u22122.4%)<\/jats:p><jats:p>Conclusions. Active smoking by young adult survivors of ELBW is associated with reduced respiratory function.<\/jats:p>","DOI":"10.1542\/peds.112.3.565","type":"journal-article","created":{"date-parts":[[2004,8,14]],"date-time":"2004-08-14T00:43:47Z","timestamp":1092444227000},"page":"565-569","source":"Crossref","is-referenced-by-count":31,"title":["Adverse Effects of Smoking on Respiratory Function in Young Adults Born Weighing Less Than 1000 Grams"],"prefix":"10.1542","volume":"112","author":[{"given":"Lex W.","family":"Doyle","sequence":"first","affiliation":[{"name":"Departments of Obstetrics and Gynaecology, and Paediatrics, the University of Melbourne, Melbourne, Australia"},{"name":"Division of Newborn Services, Royal Women\u2019s Hospital, Melbourne, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Olinsky","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Royal Children\u2019s Hospital, Melbourne, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brenda","family":"Faber","sequence":"additional","affiliation":[{"name":"Division of Newborn Services, Royal Women\u2019s Hospital, Melbourne, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Callanan","sequence":"additional","affiliation":[{"name":"Division of Newborn Services, Royal Women\u2019s Hospital, Melbourne, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2003,9,1]]},"reference":[{"key":"2021120820243229200_R1","doi-asserted-by":"crossref","unstructured":"Kitchen WH, Olinsky A, Doyle LW, et al. 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