{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:16:08Z","timestamp":1790014568157,"version":"4.0.1"},"reference-count":34,"publisher":"American Academy of Pediatrics (AAP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,11,1]]},"abstract":"<jats:p>Objectives. To investigate the effect of gestational age at birth on the frequency of ultrasound-detected brain lesions in infants born at &amp;lt;33 weeks of gestation and to investigate whether the relationship between neonatal cranial ultrasound diagnosis and neurodevelopmental outcome at 8 years of age was independent of gestational age.<\/jats:p><jats:p>Methods. Eight hundred forty-seven infants born at &amp;lt;33 weeks of gestation, admitted to a single tertiary referral center between 1983 and 1988, underwent serial neonatal cranial ultrasound. At 8 years of age neurodevelopmental outcome was assessed by structured neurologic examination, psychometric tests (Wechsler Intelligence Scale for Children), tests of visuomotor integration (Beery) and motor impairment (Henderson-Stott). Infants were subdivided into a group born at &amp;lt;28 weeks and a group born at between 28 and 32 weeks. Neurodevelopmental outcome was analyzed for each ultrasound diagnosis.<\/jats:p><jats:p>Results. Hemorrhagic lesions such as germinal matrix\/intraventricular hemorrhage and hemorrhagic parenchymal infarction were more frequent in infants born at &amp;lt;28 weeks. There was no difference in the frequency of cystic periventricular leucomalacia between the 2 groups. When neurodevelopmental outcome for each ultrasound diagnosis was compared, no significant difference was found between the 2 gestational age groups.<\/jats:p><jats:p>Conclusion. In the gestational age range studied, adverse neurodevelopmental outcome depends primarily on the type of the intracranial lesion rather than on gestational age.<\/jats:p>","DOI":"10.1542\/peds.112.5.1108","type":"journal-article","created":{"date-parts":[[2004,8,14]],"date-time":"2004-08-14T00:43:47Z","timestamp":1092444227000},"page":"1108-1114","source":"Crossref","is-referenced-by-count":71,"title":["Predictors of Long-Term Outcome in Very Preterm Infants: Gestational Age Versus Neonatal Cranial Ultrasound"],"prefix":"10.1542","volume":"112","author":[{"given":"Brigitte","family":"Vollmer","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University College London Medical School, Bloomsbury Campus, London, United Kingdom"},{"name":"Neurosciences Unit, Institute of Child Health, University College London Medical School, Mecklenburgh Square, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Roth","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University College London Medical School, Bloomsbury Campus, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny","family":"Baudin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University College London Medical School, Bloomsbury Campus, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann L.","family":"Stewart","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University College London Medical School, Bloomsbury Campus, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian G. R.","family":"Neville","sequence":"additional","affiliation":[{"name":"Neurosciences Unit, Institute of Child Health, University College London Medical School, Mecklenburgh Square, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John S.","family":"Wyatt","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University College London Medical School, Bloomsbury Campus, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2003,11,1]]},"reference":[{"key":"2021120820274773500_R1","doi-asserted-by":"crossref","unstructured":"Tin W, Wariyar U, Hey E, for the Northern National Network. Changing prognosis for babies of less than 28 weeks\u2019 gestation in the north of England between 1983 and 1994. 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