{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T13:26:55Z","timestamp":1772112415710,"version":"3.50.1"},"reference-count":35,"publisher":"American Academy of Pediatrics (AAP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,12,1]]},"abstract":"<jats:p>Increased intracranial pressure in patients with Lyme disease is an uncommon but reported finding. We discuss 2 patients from Lyme endemic areas who initially presented with headache, nausea, and vomiting and were eventually found to have increased intracranial pressure, a mild cerebrospinal fluid pleocytosis, and positive Lyme titers. It has been shown that increased intracranial pressure in association with neuroborreliosis can lead to blindness. In endemic areas, it is important for practitioners to consider Lyme disease when patients present with persistent headache, especially in those who have evidence of increased intracranial pressure.<\/jats:p>","DOI":"10.1542\/peds.112.6.e477","type":"journal-article","created":{"date-parts":[[2004,8,14]],"date-time":"2004-08-14T00:43:47Z","timestamp":1092444227000},"page":"e477-e479","source":"Crossref","is-referenced-by-count":12,"title":["Lyme Disease Presenting With Persistent Headache"],"prefix":"10.1542","volume":"112","author":[{"given":"James M.","family":"Moses","sequence":"first","affiliation":[{"name":"From the Department of Medicine, Children\u2019s Hospital Boston, Harvard Medical School, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robyn S.","family":"Riseberg","sequence":"additional","affiliation":[{"name":"From the Department of Medicine, Children\u2019s Hospital Boston, Harvard Medical School, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan M.","family":"Mansbach","sequence":"additional","affiliation":[{"name":"From the Department of Medicine, Children\u2019s Hospital Boston, Harvard Medical School, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[2003,12,1]]},"reference":[{"key":"2021121003470032900_R1","doi-asserted-by":"crossref","unstructured":"Steere AC, Malawista SE, Snydman DR, et al. 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