{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T22:42:09Z","timestamp":1791067329222,"version":"4.1.0"},"reference-count":25,"publisher":"American Academy of Pediatrics (AAP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,4,1]]},"abstract":"<jats:p>Objective. To demonstrate the clinical characteristics, radiologic findings, and neuropathological features of tetrahydrocannabinol-related posterior fossa ischemic stroke in adolescent patients.<\/jats:p><jats:p>Design. A retrospective case and chart review of 3 cases encountered at a tertiary care institution over a span of 5 years.<\/jats:p><jats:p>Setting. Inpatient and intensive care hospitalization units managing children and adolescents.<\/jats:p><jats:p>Subjects. Male adolescent patients with ischemic cerebellar stroke after use of marijuana.<\/jats:p><jats:p>Diagnostic Investigations. Computed tomography brain scans (3 subjects), magnetic resonance imaging brain study (1 subject), cerebral arteriography (1 subject), cerebellar biopsy (1 subject), and necropsy (2 subjects).<\/jats:p><jats:p>Results. Three adolescent males had similar presentations of headache, fluctuating level of consciousness or lethargy, visual disturbance, and variable ataxia after self-administration of marijuana. They developed primary cerebellar infarctions within days after the exposure that could not be attributed to supratentorial herniation syndromes and only minimally involved brainstem structures.<\/jats:p><jats:p>Conclusions. Episodic marijuana use may represent a risk factor for stroke in childhood, particularly in the posterior circulation. Early recognition of the cerebellar stroke syndrome may allow prompt neurosurgical intervention, reducing morbidity.<\/jats:p>","DOI":"10.1542\/peds.113.4.e365","type":"journal-article","created":{"date-parts":[[2004,8,14]],"date-time":"2004-08-14T00:53:04Z","timestamp":1092444784000},"page":"e365-e370","source":"Crossref","is-referenced-by-count":64,"title":["Cerebellar Infarction in Adolescent Males Associated With Acute Marijuana Use"],"prefix":"10.1542","volume":"113","author":[{"given":"Thomas","family":"Geller","sequence":"first","affiliation":[{"name":"Neurology"},{"name":"Pediatrics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Loftis","sequence":"additional","affiliation":[{"name":"Pediatrics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Brink","sequence":"additional","affiliation":[{"name":"Pathology, St Louis University School of Medicine, St Louis, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2004,4,1]]},"reference":[{"key":"2021121006130229500_R1","doi-asserted-by":"crossref","unstructured":"De Veber, Roach ES, Riela AR, Wiznitzer M. 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