{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T08:54:29Z","timestamp":1781081669913,"version":"3.54.1"},"reference-count":10,"publisher":"American Academy of Pediatrics (AAP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,7,1]]},"abstract":"<jats:p>In July 2003, the National Institute of Child Health and Human Development convened a conference, \u201cResearch on Prevention of Bilirubin-Induced Brain Injury and Kernicterus: Bench-to-Bedside.\u201d This article will provide a summary of presentations and discussions from this conference. The summary will focus on the identified knowledge gaps in 5 areas related to bilirubin-induced brain injury and kernicterus: 1) neurobiology and neuroimaging; 2) epidemiology and issues of clinical management; 3) methodologies for assessing clinical jaundice and direct and noninvasive measurement of serum bilirubin and hemolysis; 4) therapies for management of neonatal hyperbilirubinemia; and 5) public health surveillance and systems-based approaches to prevention.<\/jats:p>","DOI":"10.1542\/peds.114.1.229","type":"journal-article","created":{"date-parts":[[2004,8,14]],"date-time":"2004-08-14T00:53:04Z","timestamp":1092444784000},"page":"229-233","source":"Crossref","is-referenced-by-count":31,"title":["Research on Prevention of Bilirubin-Induced Brain Injury and Kernicterus: National Institute of Child Health and Human Development Conference Executive Summary"],"prefix":"10.1542","volume":"114","author":[{"given":"Lillian R.","family":"Blackmon","sequence":"first","affiliation":[{"name":"University of Maryland School of Medicine, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avroy A.","family":"Fanaroff","sequence":"additional","affiliation":[{"name":"Case Western Reserve University School of Medicine and Rainbow Babies and Children\u2019s Hospital, Cleveland, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tonse N. K.","family":"Raju","sequence":"additional","affiliation":[{"name":"National Institute of Child Health and Human Development, Bethesda, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2004,7,1]]},"reference":[{"key":"2021121006512877800_R1","doi-asserted-by":"crossref","unstructured":"Maisels MJ, Newman TB. Kernicterus in otherwise healthy, breast-fed term newborns. Pediatrics.\u20081995;96:730\u2013733","DOI":"10.1542\/peds.96.4.730"},{"key":"2021121006512877800_R2","doi-asserted-by":"crossref","unstructured":"MacDonald MG. Hidden risks: early discharge and bilirubin toxicity due to glucose 6-phosphate dehydrogenase deficiency. Pediatrics.\u20081995;96:734\u2013738","DOI":"10.1542\/peds.96.4.734"},{"key":"2021121006512877800_R3","doi-asserted-by":"crossref","unstructured":"Penn AA, Enzmann DR, Hahn JS, Stevenson DK. Kernicterus in a full term infant. 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