{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T20:11:03Z","timestamp":1791576663850,"version":"4.3.4"},"reference-count":11,"publisher":"American Academy of Pediatrics (AAP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,2,1]]},"abstract":"<jats:p>Objective. To call attention to constipation as a frequent sign of lichen sclerosus (LS) in girls.<\/jats:p>\n               <jats:p>Methods. A focused questionnaire was sent to parents of 24 girls with anogenital LS seen in the pediatric dermatology clinic at the Children's Hospital of Wisconsin between January 2001 and May 2004.<\/jats:p>\n               <jats:p>Results. Eighteen of 24 questionnaires were completed and returned. The average age of onset of LS was 4.2 years, but average age at diagnosis was 5.2 years; only 1 patient was diagnosed correctly by her primary care physician. Itching was the most common symptom (78%). Severe constipation was reported in 67% of patients, and 89% had at least 1 gastrointestinal complaint (bleeding with bowel movements, fissuring, soiling, fecal impaction, or constipation).<\/jats:p>\n               <jats:p>Conclusions. Childhood anogenital LS often presents with recalcitrant constipation or some other gastrointestinal complaint. Primary care physicians need to consider the diagnosis of LS and perform a thorough examination by looking for anogenital lesions when a female pediatric patient presents with unexplained constipation or other severe gastrointestinal complaints.<\/jats:p>","DOI":"10.1542\/peds.2004-1544","type":"journal-article","created":{"date-parts":[[2005,1,4]],"date-time":"2005-01-04T01:13:32Z","timestamp":1104801212000},"page":"e230-e232","source":"Crossref","is-referenced-by-count":55,"title":["Constipation as a Feature of Anogenital Lichen Sclerosus in Children"],"prefix":"10.1542","volume":"115","author":[{"given":"Mandi L.","family":"Maronn","sequence":"first","affiliation":[{"name":"Department of Dermatology, Medical College of Wisconsin, Milwaukee, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy B.","family":"Esterly","sequence":"additional","affiliation":[{"name":"Children's Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2005,2,1]]},"reference":[{"key":"2021120819201898900_R1","doi-asserted-by":"crossref","unstructured":"Fischer G, Rogers M. Treatment of childhood vulvar lichen sclerosus with potent topical corticosteroid. Pediatr Dermatol.\u20081997;14:235\u2013238","DOI":"10.1111\/j.1525-1470.1997.tb00247.x"},{"key":"2021120819201898900_R2","doi-asserted-by":"crossref","unstructured":"Powell J, Wojnarowska F. Childhood vulvar lichen sclerosus: an increasingly common problem. J Am Acad Dermatol.\u20082001;44:803\u2013806","DOI":"10.1067\/mjd.2001.113474"},{"key":"2021120819201898900_R3","doi-asserted-by":"crossref","unstructured":"Fischer GO. Lichen sclerosus in childhood. Australas J Dermatol.\u20081995;36:166\u2013167","DOI":"10.1111\/j.1440-0960.1995.tb00962.x"},{"key":"2021120819201898900_R4","unstructured":"Ridley CM. Genital lichen sclerosus (lichen sclerosus et atrophicus) in childhood and adolescence. J R Soc Med.\u20081993;86:69\u201375"},{"key":"2021120819201898900_R5","doi-asserted-by":"crossref","unstructured":"Clark JA, Muller SA. Lichen sclerosus et atrophicus in children: a report of 24 cases. Arch Dermatol.\u20081967;95:476\u2013482","DOI":"10.1001\/archderm.95.5.476"},{"key":"2021120819201898900_R6","doi-asserted-by":"crossref","unstructured":"Loening-Baucke V. Lichen sclerosus et atrophicus in children. Am J Dis Child.\u20081991;145:1058\u20131061","DOI":"10.1001\/archpedi.1991.02160090110035"},{"key":"2021120819201898900_R7","unstructured":"Trager JDK. Lichen sclerosus: managing a sensitive problem. Contemp Dermatol. June 2003; 1:1\u20137"},{"key":"2021120819201898900_R8","unstructured":"Powell J, Wojnarowska F. Childhood vulvar lichen sclerosus: the course after puberty. J Reprod Med.\u20082002;47:706\u2013709"},{"key":"2021120819201898900_R9","doi-asserted-by":"crossref","unstructured":"Neill SM, Tatnall FM, Cox NH, British Association of Dermatologists. Guidelines for the management of lichen sclerosus. Br J Dermatol.\u20082002;147:640\u2013649","DOI":"10.1046\/j.1365-2133.2002.05012.x"},{"key":"2021120819201898900_R10","doi-asserted-by":"crossref","unstructured":"Kunstfeld R, Kirnbauer R, Sting LG, Karlhofer FM. Successful treatment of vulvar lichen sclerosus with topical tacrolimus. Arch Dermatol.\u20082003;139:850\u2013852","DOI":"10.1001\/archderm.139.7.850"},{"key":"2021120819201898900_R11","doi-asserted-by":"crossref","unstructured":"Assmann T, Becker-Wegerich P, Grewe M, Megahed M, Ruzicka T. Tacrolimus ointment for the treatment of vulvar lichen sclerosus. J Am Acad Dermatol.\u20082003;48:935\u2013937","DOI":"10.1067\/mjd.2003.8"}],"container-title":["Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/115\/2\/e230\/1005537\/zpe0020500e230.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatrics\/article-pdf\/115\/2\/e230\/1005537\/zpe0020500e230.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,8]],"date-time":"2021-12-08T20:03:42Z","timestamp":1638993822000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatrics\/article\/115\/2\/e230\/67407\/Constipation-as-a-Feature-of-Anogenital-Lichen"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2,1]]},"references-count":11,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2005,2,1]]},"published-print":{"date-parts":[[2005,2,1]]}},"URL":"https:\/\/doi.org\/10.1542\/peds.2004-1544","relation":{},"ISSN":["0031-4005","1098-4275"],"issn-type":[{"value":"0031-4005","type":"print"},{"value":"1098-4275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,2,1]]}}}