{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T12:13:35Z","timestamp":1785500015014,"version":"3.56.0"},"reference-count":21,"publisher":"American Academy of Pediatrics (AAP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,5,1]]},"abstract":"<jats:p>OBJECTIVE. The UK Collaborative ECMO trial provided an opportunity to describe mortality and morbidity associated with a neonatal ECMO policy compared with conventional management. The improved survival in the ECMO group was not offset by an increase in disability at 4 years, but the children were too young to assess educational and other longer-term impacts. The objective of this study was to assess the longer-term impact of these policies at age 7 years.<\/jats:p><jats:p>METHODS. A psychologist assessed 90 of the 100 children available for follow-up without prior knowledge of treatment allocation. The assessments took place at the children's schools within 3 months of their 7th birthdays.<\/jats:p><jats:p>RESULTS. Sixty-eight of 89 (76%) children recorded a cognitive level within the normal range. Learning problems were similar in the 2 groups, and there were notable difficulties with spatial and processing tasks. A higher respiratory morbidity and increased risk of behavioral problems among children treated conventionally persisted. Progressive sensorineural hearing loss was found in both groups.<\/jats:p><jats:p>CONCLUSIONS. The underlying disease processes appear to be the major influence on morbidity at 7 years. The beneficial influence of an ECMO policy is still present at 7 years.<\/jats:p>","DOI":"10.1542\/peds.2005-1167","type":"journal-article","created":{"date-parts":[[2006,4,25]],"date-time":"2006-04-25T00:29:44Z","timestamp":1145924984000},"page":"e845-e854","source":"Crossref","is-referenced-by-count":165,"title":["United Kingdom Collaborative Randomized Trial of Neonatal Extracorporeal Membrane Oxygenation: Follow-up to Age 7 Years"],"prefix":"10.1542","volume":"117","author":[{"given":"Helena","family":"McNally","sequence":"first","affiliation":[{"name":"Medical Sciences Division, University of Oxford"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte C.","family":"Bennett","sequence":"additional","affiliation":[{"name":"Neonatal Unit, John Radcliffe Hospital, Oxford, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Elbourne","sequence":"additional","affiliation":[{"name":"Medical Statistics Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Field","sequence":"additional","affiliation":[{"name":"Neonatal Unit, Leicester Royal Infirmary, Leicester, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the UK Collaborative ECMO Trial Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2006,5,1]]},"reference":[{"key":"2021120823260663600_R1","doi-asserted-by":"crossref","unstructured":"UK Collaborative Trial Group. 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